肌酐

Healthy SD male rats were given DEG with the dose of 8 mL/kg body weight (intraperitoneal injection I.P.). The level of the serum Cr, BUN and CO2CP(CO2 Combining Power CO2CP)were tested before and after the injection the 2nd , 5th , 7th, and 14th day. The nephridial tissue of all the rats was taken for pathological examinations.

选用健康雄性SD(Sprague-Dawley)大鼠，腹腔注射8 mL/kg的DEG，于注射前和注射后第2天、5天、7天以及14天尾静脉采血检测血肌酐、尿素氮和CO2结合率(CO2CP)，收集死亡大鼠及第7天和14天处死大鼠的肾组织进行病理检查。

TCM group were intragastric administrated with Shenluotong 25 g/kg.d, Control group and the model group were intragastric administrated with benazepril 10 mg/kg.d, Normal group and model group were given equivalent physiological saline.24 hour urinary protein,Scr and BUN of different groups, and the expression of CTGF mRNA in nephridial tissue were detected.

检测各组大鼠24 h尿蛋白、血清尿素氮、肌酐和肾组织CTGF mRNA的表达。

Results Compared with CRF group, nephrogenic hypertension of hemin group was reduced significantly at the 6th, 8th, 10th week after operation, and followed with the decrease of serum creatinine, BUN,urinary protein and the improvement of nephrogenic anemia at the 10th week after operation. Hemin not only increased the expression of HO-1, reduced the expression of ET-1 in the kidney, but also increased the concentration of carbon monoxide, reduced the level of ET-1 in the plasm.

同时，在术后第10周hemin组比CRF组血肌酐、尿素氮、尿蛋白显著降低(P＜0.05)，贫血明显改善(P＜0.05)；肾组织中HO-1表达明显增加，血浆中内源性CO水平明显升高，肾组织和血浆中ET-1水平明显降低(P＜0.05)。

Urinary NAG activities were measured by nitrophenol colorimetric analysis technique.

用生化法测定血肌酐，用硝基苯酚比色法测定尿NAG。

Methods Ninety patients with diabetic nephropathy were randomly divided into two groups: control group and observative group. The routine treatment including administration of diabetic diet, blood glucose control and lossing blood pressure for 8 weeks. Ramipril was performed in control group for 8 weeks. Fasting blood glucose, total cholesterol, triglyceride, serum creatinine, urinary albumin excretion rate and plasma lipoprotein were detected and compared before treatment and 8 weeks later in two group.

90例DN患者随机分为两组，治疗组46例，对照组44例，两组患者均给予糖尿病饮食、控制血糖和降血压等常规治疗，对照组给予雷米普利，观察组在对照组治疗的基础上给予氟伐他汀，两组疗程均为8周；于治疗前和治疗8周后检测两组空腹血糖、总胆固醇、甘油三脂、血肌酐、尿微量白蛋白排泄率和血浆脂蛋白，并进行比较。

Methods: A total of 42 eligible patients with ARF were randomly divided into two groups. Besides routine treatments for ARF, patients in therapeutic group were administrated with 5 000 U EPO, twice a week. Clinical parameters of patients in therapeutic group and control group such as duration of oliguria stage, time for creatinine decreased in half, hemoglobin, hematocrit, and albumin and so on were compared.

急性肾功能衰竭患者共42例，分为两组，治疗组在基础治疗的基础上，给予促红细胞生成素5 000 U，每周2次，对比两组患者少尿期持续时间、肌酐减半时间、血红蛋白、红细胞压积、白蛋白等指标。

Methods A total of 2 285 community residents, at the age of 51±16 years, from 4 different communities in Beijing, were randomly recruited in this cross-sectional investigation. Questionnaire was used to collect their medical history. Their PWV was detected by oscillometry. Laboratory tests were performed to detect their basal biochemical parameters including serum glucose, uric acid, lipid, and creatinine.

北京4个社区入选2 285名18-96岁居民，平均年龄51±16岁，用问卷调查方法采集病史，自动示波测量仪检测PWV，同期化验血脂、肌酐、尿酸、血糖等指标，简化的MDRD公式估测肾小球滤过率。

Low-fat diet was given to those patients. The changes of total cholesterol,high-density lipoprotein,low-denstiy lipoprotein,triglyceride,aproprotein A, aproprotein B, creatinine, glutamic oxalacetic transaminase, glutamic pyruvic transaminase were measured before and after 1,3,6,12 months of Simvastatin therapy(10mg,qd).

所有患者均采取低脂饮食，测定患者血总胆固醇、高密度脂蛋白、低密度脂蛋白、甘油三酯、载脂蛋白A、载脂蛋白B、肌酐，谷草转氨酶及谷丙转氨酶等各参数数值；然后给予辛伐他汀10 mg，每晚一次口服，测定用药后1，3，6，12个月后以上各参数值的变化。

Results According to the treatment group, The total protein、albumin、globulin、the former albumin、serum glucose are higher than that of the control group; the Immunoglobulin (IgG、IgA、 IgM) are significantly higher than that of the control group, and the urea is significantly lower than that of the control group. Other indicators: total bilirubin、glutamic pyruvic transaminase、glutamic oxalacetic transaminase、alkaline phosphatase、creatinine、hemoglobin and the red blood cell count have no significant difference between the two groups.

结果 治疗组总蛋白、白蛋白、球蛋白、前白蛋白、血糖比对照组高；尿素比对照组明显减低；免疫球蛋白（IgG、IgA、IgM）比对照组明显升高；总胆红素、谷丙转氨酶、谷草转氨酶、碱性磷酸酶、肌酐、血红蛋白、红细胞计数等项，两组无明显改变。

Oxonic acid, an uricase inhibitor used in establishing hyperuricemia animal model, can disturb current uric acid biochemical assay.

本部分研究选用国产C_(18)色谱柱，探索同时检测次黄嘌呤、黄嘌呤、尿酸、尿囊素和肌酐的方法。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。