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The mouse was carried out half nephric duct ligation to induce the renal interstitial fibrosis animal model,afterwards,to set up three groups,control group,sham operation group(intragastric administration with normal sodium according to 10ml/kg weight),treatment group...

采用小鼠单侧输尿管结扎法诱导肾间质纤维化的动物模型,用盐酸青藤碱治疗,并设对照组、假手术组(小鼠每日按10m l/kg体重用生理盐水灌胃,直至治疗结束)、治疗组(选用正清风痛宁缓释片按每日30mg/kg体重给小鼠灌胃,连续3周,),检测血尿素氮、血肌酐、血清层粘连蛋白、纤维连接蛋白的含量,免疫组化法测肾脏组织转化因子β1(TNF-β1)的表达并进行肾脏病理学的观察。

MethodsSodium Hyaluronate was injected into the palatoglossal arch, palatopharyngeal arch and root of the tongue of eight Wistar rats. An electroencephalogram, electromyogram and oronasal airflow were recorded by PSG before and 4 weeks after injection when rats were under light anesthesia, which was expected to be similar to the sleep state.

方法将8只Wistar大鼠的双侧舌腭弓、咽腭弓及舌根处注射透明质酸钠,分别于注射前及注射后4周,以浅状态模拟睡眠状态,用多导睡眠仪监测动物的脑电、肌电及口鼻气流。

The liver and kidney were partly removed and fixed with 4 % paraform phosphate buffer. The remnant of the liver was stored in liquid nitrogen and -80℃. 4.examination: Serum: ALT, AST, BUN, Scr in serum were measured by biochemical analyses and MDA,SOD by spectrophotometric methods and HA , LN, C-IV by radioimmunological methods.

指标检测:血清:全自动生化分析仪检测血清中谷丙转氨酶、谷草转氨酶、尿素氮、血肌酐的含量,放射免疫的方法检测血清透明质酸、层粘连蛋白、IV型胶原,分光光度计法检测血清中超氧化物歧化酶活性及丙二醛的变化。

Results In 9 cases of endometrial biopsy of materials by uterine curettage, the cells of endometrial stromal sarcomas of 6 cases were well differentiated and like stromal cells of endometrial hyperplasia; the cells of endometrial stromal sarcomas of 3 cases were poor differentiated, the cells of 2 were like that of malignant lymphoma, and another like that of pleomorphous sarcoma. In 9 cases were found the distribution of vessels cluster like endometrial corkscrew small artery. The tumor cells were grew along lymphatic or protruded in lymphatic, and there were small islands or small pieces of tumor cells in the interspace of muscles in 2 cases. The contrastive observation of the specimens of resected uterines of 9 cases confirmed the valve of above features to the confessed diagnosis of endometrial stromal sarcomas in the materials of endometrial biopsy or uterine curettage.

有3例分化差者,其中2例酷似恶性淋巴瘤,1例酷似多形性肉瘤。9例均见簇状分布的子宫内膜螺旋小动脉样的小血管分布,2例见瘤组织沿淋巴管和突入淋巴管内生长及小片平滑肌组织的肌间隙内有小灶状或小片状瘤组织分布。9例子宫切除标本的对比观察,进一步证实了上述特征对宫内膜活检或刮出物确诊子宫内膜间质肉瘤的价值。

Signalling through CXCR4 mediates actin polymerization and pseudopodia formation in cells, and induces chemotactic and migration to target organs. In addition, CXCR4-SDF-1 axis can promote tumor angiogenesis and growth.

CXCR4在肿瘤组织中的表达明显高于正常组织,而肿瘤常见转移部位均为CXCR4的配体基质细胞衍生因子-1(stromal cell derived factor-1,SDF-1)表达丰富的器官,SDF-1与CXCR4结合后可使细胞肌动蛋白丝聚合,形成伪足,从而定向诱导肿瘤细胞迁移到特定的靶器官;此外,CXCR4与其配体SDF-1相互作用可以促进局部新生血管作用,利于肿瘤生长。

The effects of plasmid pcDNA3 on Ca (superscript 2+) transport of sarcoplasmic reticulum in ischemic skeletal muscle was investigated.

在大鼠肢体缺血模型上观察了质粒pcDNA3月对缺血骨骼肌肌浆网Ca(上标 2+)转运的影响。

Glucocorticoid: For early skin swelling and serositis, myositis, interstitial lung inflammation, and so effective, and for vascular damage and fibrosis invalid, side effects of high-dose applications, especially for the existing kidney damage Patients easily add vascular damage, and even cause acute renal failure, it is necessary to be careful when using the dosage and the treatment should be individualized, based on clinical performance.

糖皮质激素:对于早期皮肤的肿胀及浆膜炎、肌炎、肺间质炎症等有效,而对于血管损害和组织纤维化无效,大剂量应用时副作用大,尤其是对于已有肾脏损害的患者易加重血管损害,甚至引起急性肾功能衰竭,故使用时须慎重,使用剂量及疗程应个体化,依据临床表现而定。

OBJECTIVE: To investigate the influence of pulse electric stimulation on the expression of the transcriptive factors, myocyte enhancer factor 2C mRNA, in the course of differentiation of BMSCs into cardiomyocytes.

目的:在诱导骨髓间充质干细胞向心肌细胞分化过程中,观察低压脉动电刺激对肌细胞增强因子2C基因表达的影响。

Collagen, a most abundant protein, is widely distributed in skins, tendons, cartilages and constitutes about 25%-30% by weight of all proteins in human or other animal bodies. Collagen structure is characterized by containing domains with repetition of the Gly-Xaa-Yaa prolinrich tripetide and the trimeric collagen triplehelices.

胶原是动物体内含量最多、分布最广的蛋白质,广泛分布于结缔组织、骨骼、内脏细胞间质及肌腔、韧带、巩膜等部位,占人体或其他动物体总蛋白含量的25%~33%。

After a single intramuscular injection of plasmid hlL-6 Cdna on 6.5 Gy-irradiated mice, the IL-6 level showed less changes in unirradiated mice.

经6.5 Gy照射的小鼠一次肌内注射表达IL-6的质粒DNA后,用ELISA方法检测血浆IL-6水平,以蛋白表达量评价基因转移效率。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。