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肌蛋白

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Experiments show that Ang Ⅱ activates JNK mediated by AT〓, and JNK increases transcription activity of c-Jun by phosphorylating c-Jun amido-terminal, and induces expression of c-Fos gene. c-Jun and c-Fos form transcriptional factor activated protein-1 complex. AP-1 may stimulates genes which correlate with cardiovascular remodeling expression, such as transforming growth factor, collagen type Ⅰ and Ⅲ, skeletal muscle α-actin,β-MHC, atrial natriuretic factor.

实验表明,在心肌和血管平滑肌细胞Ang Ⅱ通过AT〓介导激活JNK;JNK通过磷酸化c-Jun氨基末端增加c-Jun的转录活性并诱导c-Fos基因表达,c-Jun和c-Fos蛋白形成转录因子复合物激活蛋白-1(AP-1),并刺激各种心血管重塑相关基因如转化生长因子-β1(TGF-β1)、Ⅰ,Ⅲ型胶原、骨骼肌α-actin、β-MHC(β-myosin heavy chain,β-肌球蛋白重链)、心钠素的表达。

Then correlation analysis and ROC curve analysis were performed.

对262例受试者(正常103例,糖耐量减低98例,糖尿病61例)测定尿白蛋白、尿转铁蛋白、尿肌酐;进行相关分析及ROC曲线分析。

The expression of caveolin-1 mKNA and immunostaining were strong in myometrum on dey 1 of pregnancy.

在妊娠第1天的子宫肌层中,可以检测到小窝蛋白-1 mRNA和蛋白的表达。

Here we show that phenylarsine oxide and diamide (both were inhibitors for protein tyrosine phosphatases), but not genistein (an inhibitor for protein tyrosine kinases), adenosine, wortmannin and LY294002 (all were inhibitors for phosphatidylinositol 3- and 4-kinases), could inhibit P-selectin exocytosis on activated platelets and could abolish the P-selectin mediated aggregation of activated platelets to neutrophils.

我们发现蛋白酪氨酸磷酸酶的抑制剂phenylarsine oxide和diamide能够抑制P-选凝素从活化的血小板中外排出来,并能够抑制P-选凝素介导的活化的血小板在白细胞表面的粘附,而蛋白酪氨酸激酶的抑制剂genistein,磷脂酰肌醇3-或4-激酶的抑制剂adenosine、wortmannin和LY294002在这些实验中没有作用。

Here we show that phenylarsine oxide and diamide (both were inhibitors for protein tyrosine phosphatases), but not genistein (an inhibitor for protein tyrosine kinases), adenosine, wortmannin and LY294002 (all were inhibitors for phosphatidylinositol 3-and 4-kinases), could inhibit P-selectin exocytosis on activated platelets and could abolish the Pselectin mediated aggregation of activated platelets to neutrophils.

我们发现蛋白酪氨酸磷酸酶的抑制剂phenylarsine oxide和diamide能够抑制P-选凝素从活化的血小板中外排出来,并能够抑制P-选凝素介导的活化的血小板在白细胞表面的粘附,而蛋白酪氨酸激酶的抑制剂genistein,磷脂酰肌醇3-或4-激酶的抑制剂adenosine、wortmannin和LY294002在这些实验中没有作用。

Immunohistochemistry showed a positive reaction to cytokeratin and a negative reaction with smooth muscle actin..Conclusions:.The Alcian blue negative stain, the negative reaction to SMA, and the fact that the patient is still alive 10 years after exenteration favored the diagnosis of basal cell adenocarcinoma.

免疫组化显示,细胞角蛋白反应阳性,平滑肌肌动蛋白(结论:阿尔辛蓝染色为阴性、SMA反应阴性及病人在眶内容去除术10年后仍然存活的事实都倾向于基底细胞腺癌的诊断。

Immunohistochemistry showed a positive reaction to cytokeratin and a negative reaction with smooth muscle actin..Conclusio :.The Alcian blue negative stain, the negative reaction to SMA, and the fact that the patient is still alive 10 years after exenteration favored the diagnosis of basal cell adenocarcinoma.

免疫组化显示,细胞角蛋白反应阳性,平滑肌肌动蛋白(结论:阿尔辛蓝染色为阴性、SMA反应阴性及病人在眶内容去除术10年后仍然存活的事实都倾向于基底细胞腺癌的诊断。

Among the genes were glyceraldehyde 3-phosphate dehydrogenase, serine protease inhibitors, mitochondrion coding region, part of myosin heavy chain gene and two new genes, respectively.

结果 筛选出 6种蛋白分子基因:3-磷酸甘油醛脱氢酶,丝氨酸蛋白酶抑制剂,线粒体编码蛋白,肌球蛋白部分重链基因以及两个未知新基因。

They are involed of intracellular movements in plant and animal cells.

细胞骨架的大部分主要是由可收缩的蛋白肌动蛋白组成的细长的微丝。

Objective To clone, express and characterize the panallergen profilin from the pollen of Caryota mitis Lour.

目的克隆并表达短穗鱼尾葵花粉中泛变应原肌动蛋白抑制蛋白。

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