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BACKGROUND: Studies concerning muscle-derived stem cell transplantation mainly focused on treatment of muscular dystrophy. There are no studies on muscle-derived stem cells for treatment of denervated amyotrophy combined therapy.

背景:目前,国内外有关肌源性干细胞移植的研究主要集中在治疗肌营养不良性萎缩症方面,尚未见涉及将肌源性干细胞应用于失神经肌萎缩综合治疗的报道。

This study was to evaluate the influence of masseter muscle on the craniofacial growth and development by using the botulinum neurotoxin to cause the masseter muscle atrophy.

中文摘要本研究目的是藉由将肉毒杆菌神经毒素注射入大白鼠咬肌,使咬肌萎缩,来探讨咬肌对颅颜型态及生长发育的影响。

Objective To observe the changes of myoblast prolifer ation dynamics of atrophic skeletal muscle after denervation in rats and their r elationship with muscle atrophy.

目的 观察大鼠骨骼肌失神经支配后肌萎缩和成肌细胞增殖动力学的动态变化及其与骨骼肌萎缩的关系。

DM1 and DM2 gene were amplified by PCR,tested by agarose electrophoresis, then analyzed by genetic analyzer. Results: Myotonia and muscle weakness were the main manifestations associated with heart block (7/8) and cataract (6/7). Electromyologram showed myopathic abnormalities not only in patients but also in other members of the family (5/6). The CTG repeats in DM1 and CCTG repeats in DM2 were all in normal range.

结果:该家系患者除有肌强直、肌萎缩等表现外;心电图检查:心脏传导阻滞(7/8);裂隙灯检查:白内障(6/7);肌电图检查:患者组有强直电位发放(5/5),无临床症状成员也存在肌源性损害(5/6);但该家系无DM1位点n和DM2位点n的重复数增加。

Deletions that terminate in in-frame codons, do not prevent translation of dystrophin and result in a truncated protein, still able to bridge actin and sarcolemma.

缺失的终止在框架密码子,并没有妨碍在截短的抗肌萎缩蛋白翻译和结果,仍然能够弥合肌动蛋白,肌膜。

Results ①After 14 days of tail suspension, the ratio of wet weight of soleus muscle ...

结果 ①模拟失重14d后,比目鱼肌发生明显的萎缩,比目鱼肌湿重体重比由吊尾前的 38.8(mg·10 0 g- 1 )降低到 2 3.1,而吊尾加CLFS 14d后比目鱼肌湿重体重比仅下降到 32 。5 ,表明CLFS可有效的防止模拟失重所造成的肌萎缩。

Results All four cases of Hirayama disease occured in adolescents,three were male,one was female,characterized by muscular atrophy in the hand and forearm with ulnar muscles worsening;the brachioradial was spare.Fine postural tremor (4 cases) and cold paresis (3 cases) were demonstrated.

结果 4例患者有3例为青春期男性,1例为青春期女性,主要表现为局限于手和前臂的肌萎缩,尺侧肌肉萎缩较重,上肢呈斜坡样。4例手指伸展时出现震颤;3例伴寒冷麻痹。

BACKGROUND: Duchenne muscular dystrophy is a cureless disease, it is a severe result of progressive atrophy of muscle cells, which caused by various defects.

背景:杜氏型肌营养不良的肌细胞损伤并非单一细胞受损,而是多因素缺陷导致肌细胞进行性萎缩的严重后果,患儿一经确诊即被告之无法医治。

Fund Project:Tackle Key Program of Liaoning Province, No. BACKGROUND: Duchenne muscular dystrophy is a cureless disease, it is a severe result of progressive atrophy of muscle cells, which caused by various defects.

背景:杜氏型肌营养不良的肌细胞损伤并非单一细胞受损,而是多因素缺陷导致肌细胞进行性萎缩的严重后果,患儿一经确诊即被告之无法医治。

The prevalence and degree of fatty muscle atrophy were evaluated with magnetic resonance imaging in the abductor digiti minimi, flexor digitorum brevis, abductor hallucis, and quadratus plantae muscles in 80 asymptomatic volunteers (mean age, 48 years; range, 23-84 years) and 80 patients with foot pain (mean age, 48 years; range, 20-86 years).

对80例无症状志愿者(平均年龄48岁,范围23-84岁)和80例足痛患者(平均年龄为48岁,范围20-86岁)小趾展肌、趾短屈肌、拇展肌和足底方肌进行磁共振成像以估计脂肪肌内萎缩的发病率和程度。

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