肌肉

DMD eventually affects all voluntary muscles, as well as heart and breathing muscles.

dmd的最终影响到所有自愿肌肉以及心脏和呼吸肌。

DMD is caused by a mutation of the gene for dystrophin, a protein in the muscles.

DMD源于肌肉中一种称为肌营养不良蛋白的基因突变。

But when the patient is younger, It is difficult to differentiate DMD from BMD.

基因变异检测也不能区分二者，而检测肌肉中dystrophin的改变是鉴别诊断的重要方法。

In DMD, dystrophin is missing and the muscle membrane is easily damaged.

在DMD，肌营养不良蛋白丢失和肌肉膜容易损坏。

Or doughy, like the proximal muscles in dermatomyositis?

或柔软无力，象皮肌炎的近心端肌肉？

I'm training my abs, doing endurance training and everyday I'm training my upper- and downer body.

但是在家的时候我会锻炼我的腹部肌肉，做一些耐力训练。

Supplemental probiotics tended to increase muscle pH and decrease the loss of drib water.

两种益生素均有提高贵妃鸡肌肉PH和降低滴水损失的趋势。

Dysarthria is a speech disorder resulting from damage to the motor execution system of the central nervous system and resulting in muscular weakness and reduction in motor control.

构音困难肇因於中央神经系统中运动执行系统的损害，发音不良会导致肌肉无力且降低运动的控制。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73～79. The fragments of abnormal alleles were 380～402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18～40, fragments from 202～270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变，CAG三核苷酸重复73～79次，异常等位基因片段长380～402bp，均为杂合子；正常人CAG三核苷酸重复18～40次，等位片段长200～270bp，电生理发现MJD的SCV减慢比MCV明显，而下肢的MCV、SCV又较上肢明显，BAEP、VEP均有不同程度的潜伏期延长或波的异常；MJD的父亲遗传早于母亲，进展也较块，临床以小脑性共济失调为突出症状，其次为构音障碍、突眼等，肌肉萎缩仅见于晚期病人；MRI示小脑萎缩较明显，脑干萎缩并不严重，未见明显的颈髓萎缩。

It is usually caused by muscular irritation as well as joint dysfunction.

它通常是由于肌肉的刺激，以及关节功能障碍。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。