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New study found that phosphocreatine cound penetrate through cell membrane to protect mitochondrion by inhibiting permeability transition pore opening and reduce cell apoptosis.

新的研究发现,磷酸肌酸还可以透过细胞膜抑制膜通透改变孔道的开放保护线粒体,减少细胞凋亡。

In addition,phosphocreatine cound increase left ventricular ejection fraction,promote heart function,increase blood flow of coronary and improve circulation of coronary.

此外,磷酸肌酸还可以提高左室射血分数,改善心功能,增加冠状动脉流量,改善冠状动脉循环。

To investigate the variations of actin and ezrin protein and the interference of phosphocreatine of newborn porcine RTC cell during hypoxia, and discussion the mechanism of renal deficiency of newborn asphyxia.

目的:研究缺氧新生猪RTC细胞actin及ezrin蛋白的变化和磷酸肌酸的干预,探讨新生儿窒息肾功能损伤的发病机制。

Now phosphocreatine has been applicated in extracorporeal circulation surgery,heart failur,myocardiac infarction,arrhythmia and coronary heart disease.

目前,磷酸肌酸不但应用于体外循环手术中,还应用于治疗心力衰竭、心肌梗死、心律失常、冠状动脉粥样硬化性心脏病。

The levels of serum phosphocreatine kinase, lactic dehydrogenase, aspartate aminotransferase, malondialdehyde and superoxidedismutase were monitored dynamically before the experiment and 2, 12, 24, 48, 96, hours as well as 1 and 2 weeks after looseing the tournique.

在实验前以及松开止血带后2、12、24、48、96h、1周和2周后连续、动态检测血浆磷酸肌酸激酶、乳酸脱氢酶、谷草转氨酶、丙二醛浓度和超氧化物歧化酶活性。

Metabolic status of the heart was evaluated by monitoring ATP,phosphocreatine and intracellular pH continuously with 31 P NMR spectroscopy.

运用31PNMR谱仪同步测定心肌ATP、细胞内pH和磷酸肌酸。

The identified proteins were divided into two following categories: one is regulatory proteins, for example, caffeic acid 3-O-methyltransferas, HSP70, glyoxalase I , actin, and so on. They are involved in protein biosynthesis and processing, cellular structural organization and stress responses. The other is function proteins, for instance, ascorbate peroxidase, cytoplasmic malate dehydrogenase, cytosolic phosphoglycerate kinase, S-adenosyl methionine synthetase, ATP synthase, and so on. They are involved in photosynthesis, photorespiration, redox homeostasis, and metabolisms.

通过分析可以将这些差异蛋白分为两大类:第一类是调节性蛋白,如咖啡酸三氧转甲基酶,热激蛋白70,醛酮变位酶I,肌动蛋白等,它们主要参与蛋白质的合成和加工、胁迫响应、细胞骨架稳定等过程;第二类是功能性蛋白,如抗坏血酸过氧化物酶,细胞质苹果酸脱氢酶,细胞质磷酸甘油酸激酶,S-腺苷蛋氨酸合成酶,ATP合酶等,它们则参与氧化还原平衡、光合作用、光呼吸和各种代谢等过程。

The rats were killed 10 weeks later to determine the weight of femur, bone mineral density and bone gla protein, alkaline phosphatase, calcium and phosphonium in serum and Ca, hydroxyproline and creatinine in urine.

实验10 w后处死大鼠,测定股骨重量、骨密度,检测血清骨钙素、碱性磷酸酶、钙、磷,同时检测尿钙、羟脯氨酸及肌酐等指标。

Methods: The experimental myocardial infarction was induced by high level ligation of the anterior descending of the left coronary artery in rabbits. The protective effects were determined by the changes in ECG, the activity of serum creatin phosphorate kinase and infarct sizes.

采用结扎家兔冠状动脉前降支造成急性心肌梗塞的病理模型,用心电图、血清磷酸肌酸激酶活性和梗死面积评价TFGb对心肌缺血的保护作用。

Methods Blood samples were collected from the precaval vein of 6 female Tibet mini-pigs to test the concentration of sex hormones including T,P4,E2,FSH,LH,PRL and blood biochemical indexes including Ca, Mg, P, ALP, Cre, CHO, TP, and Alb during the estrous cycle.

对6头雌性西藏小型猪在发情周期内的发情当天、第5天、第10天、第15天、再次发情时分别采血5 mL并分离血清,应用放射免疫法测定血清睾酮、孕酮(P4)、雌二醇(E2)、促卵泡生成激素、促黄体生成激素、泌乳素;用自动生化仪测定血清钙、镁、磷、碱性磷酸酶、肌苷、总胆固醇、总蛋白、白蛋白。

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