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Experiments show that Ang Ⅱ activates JNK mediated by AT〓, and JNK increases transcription activity of c-Jun by phosphorylating c-Jun amido-terminal, and induces expression of c-Fos gene. c-Jun and c-Fos form transcriptional factor activated protein-1 complex. AP-1 may stimulates genes which correlate with cardiovascular remodeling expression, such as transforming growth factor, collagen type Ⅰ and Ⅲ, skeletal muscle α-actin,β-MHC, atrial natriuretic factor.

实验表明,在心肌和血管平滑肌细胞Ang Ⅱ通过AT〓介导激活JNK;JNK通过磷酸化c-Jun氨基末端增加c-Jun的转录活性并诱导c-Fos基因表达,c-Jun和c-Fos蛋白形成转录因子复合物激活蛋白-1(AP-1),并刺激各种心血管重塑相关基因如转化生长因子-β1(TGF-β1)、Ⅰ,Ⅲ型胶原、骨骼肌α-actin、β-MHC(β-myosin heavy chain,β-肌球蛋白重链)、心钠素的表达。

Objective To observe the effect of Na_2ATP on afferent discharge of muscle spindle.

目的:探讨三磷酸腺苷二钠盐(Na2ATP)对肌梭传入放电的影响。

Methods:A rabbit model was developed with scald complicated with artificial infection of Pseudomonas aeruginosa.Studies were carried out by using the combat trauma spray group and the solution group.At day1,2,4,7,14,post experiments,rabbit serum was collected,the body temperatures of animals were taken,and such inflammatory factors as white cell count,serum levels of NO 2-/NO 3-,serum levels of tumor necrosis factor,serum superoxide anion,as well as GPT,AKP,aspartate carbamyl transferase,urea nitrogen were also collected to measure the functions of both the kidney and liver.

采用烫伤合并人工感染绿脓杆菌的家兔模型,用战伤喷剂与溶剂组于实验前和实验后第1、2、4、7、14天采集家兔血清,测量体温,检测白细胞数、血清NO 2-/NO 3-水平、血清肿瘤坏死因子水平、血清超氧阴离子等炎性因子水平以及谷丙转氨酶、碱性磷酸酶、天冬氨酸转移酶、肌苷和尿素氮等肝肾功能指标水平。

The effects of baicalin on electro cardiogram,serum CPK and myocardial malonialdehyde and superoxide dismutase were observed in rats.

观察黄芩甙对各组大鼠心电图、血清磷酸肌酸激酶及心肌组织超氧化物歧化酶和脂质过氧化物丙二醛的影响。

It is composed mostly of B vitamins, phosphoric acid, choline, linoleic acid and inositol.

它是组成,其中大部分B族维生素,磷酸,胆碱,亚油酸和肌醇。

Objective In order to improve heart function,creatine phosphatewas used in the perioperative period of cardiac surgery.

目的 探讨围术期应用磷酸肌酸对改善心脏手术患者的心功能和血流动力学状态的作用。

Phytase is a kind of biological enzyme, which can decompound phytic acid and then release the inorganic phosphorus, inositol and protein, amino acid, microelement, combined with phytic acid, etc.

植酸酶是一种新型食品与饲料添加剂,它能催化植酸水解为肌醇及无机磷酸,促进微量元素及蛋白质等营养成分的吸收。

In blood, luteotropin significantly increased at DCAB 400 fed sample, estradiol (E2) and urea decreased at DCAB 400 and 500 fed sample. However, Lactate dehydrogenate, creatine phosphokinase and total protein had a significant increase for DCAB 300 and 400 fed sample.

血液指标中,DCAB 400组提高了促乳素,DCAB 400和500组提高了雌二醇浓度和尿素;DCAB 300和400组乳酸脱氢酶、肌酸磷酸激酶和总蛋白显著提高;处理组钙含量显著高于对照组。

Here we show that phenylarsine oxide and diamide (both were inhibitors for protein tyrosine phosphatases), but not genistein (an inhibitor for protein tyrosine kinases), adenosine, wortmannin and LY294002 (all were inhibitors for phosphatidylinositol 3- and 4-kinases), could inhibit P-selectin exocytosis on activated platelets and could abolish the P-selectin mediated aggregation of activated platelets to neutrophils.

我们发现蛋白酪氨酸磷酸酶的抑制剂phenylarsine oxide和diamide能够抑制P-选凝素从活化的血小板中外排出来,并能够抑制P-选凝素介导的活化的血小板在白细胞表面的粘附,而蛋白酪氨酸激酶的抑制剂genistein,磷脂酰肌醇3-或4-激酶的抑制剂adenosine、wortmannin和LY294002在这些实验中没有作用。

Here we show that phenylarsine oxide and diamide (both were inhibitors for protein tyrosine phosphatases), but not genistein (an inhibitor for protein tyrosine kinases), adenosine, wortmannin and LY294002 (all were inhibitors for phosphatidylinositol 3-and 4-kinases), could inhibit P-selectin exocytosis on activated platelets and could abolish the Pselectin mediated aggregation of activated platelets to neutrophils.

我们发现蛋白酪氨酸磷酸酶的抑制剂phenylarsine oxide和diamide能够抑制P-选凝素从活化的血小板中外排出来,并能够抑制P-选凝素介导的活化的血小板在白细胞表面的粘附,而蛋白酪氨酸激酶的抑制剂genistein,磷脂酰肌醇3-或4-激酶的抑制剂adenosine、wortmannin和LY294002在这些实验中没有作用。

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