肌病的

Sum up as follows now. This group uses 1 clinical data ancon vein is pressed determine heart function of the patient 44, male 24, female 20; age 46 years old of ~79 year old, average 56 years old of; classification by function of new York heart, heart failure Ⅲ spends 6,Ⅱ spends 23,Ⅰ spends 15; right heart failure 31, complete heart failure heart disease of sex of source of 13; lung 14, hypertensive heart disease 8, coronary heart disease 5 (among them acute cardiac muscle straightens dead 2), outspread sex cardiac muscle is ill 7, rheumatism sex heart disease 4, hypertensive heart disease is amalgamative coronary heart disease 3, be short of disease of cardiac muscle of courage and uprightness 2, congenital heart disease 1. 2 detect 2.1 equipment treat the method dish 1, l measure press glass to be in charge of 1 (long 30cm, internal diameter 4mm), also can use measure a head to press a canal to replace, 10mL injector 1, 12500U heparin fluid 1. 2.2 operations patient is taken smooth lie, make be exhibited outside the upper arm show ° of 45 °~60 with trunk, and difficulty breathes like the patient in same horizontal; with right atrium, desirable lie partly, arm height is equivalent to the 2nd costal region.

现总结如下。1临床资料本组采用肘静脉压测定病人的心功能44例，男24例，女20例；年龄46岁~79岁，平均56岁；按纽约心功能分级，心力衰竭Ⅲ度6例，Ⅱ度23例，Ⅰ度15例；右心力衰竭31例，全心力衰竭13例；肺源性心脏病14例，高血压心脏病8例，冠心病5例(其中急性心肌梗死2例)，扩张性心肌病7例，风湿性心脏病4例，高血压心脏病合并冠心病3例，缺血性心肌病2例，先天性心脏病1例。2检测方法2.1设备治疗盘1个，L型测压玻璃管1个(长30cm，内径4mm)，也可以用测脑压管代替，10mL注射器1具，12500U肝素液1支。2.2操作病人取平卧位，使上臂外展和躯干呈45°~60°，且和右心房在同一水平面；如病人呼吸困难，可取半卧位，手臂高度相当于第2肋间。

Methods The admitted cardiopathy patients in the same periods were divided into dilated cardiomyopathy group (144 cases) and ischemic cardiomyopathy group (170 cases).

将同期入院的心肌病患者分为扩张型心肌病组(144例)和缺血性心肌病组(170例)。

By clinic observation and study we recognize that this theory is inconsequent to clinical pathology.

通过多年的临床观察和研究我们发现这一理论可能存在与临床病理变化不一致的方面，为此我们提出扩张型心肌病的基因缺陷、感染和自身免疫等因素首先导致心脏骨架结构的损害和扩大，进而发生心肌细胞的变性、坏死和纤维化过程，最后导致心功能降低和心力衰竭。

Now clinical treating methods mainly depend on theoretic foundation of heart expanding and failure causing by cardiac denaturation, necrosis and fibrosis leading by gene defect, virus infection and self-immunity et cetera. By clinic observation and study we recognize that this theory is inconsequent to clinical pathology.

通过多年的临床观察和研究我们发现这一理论可能存在与临床病理变化不一致的方面，为此我们提出扩张型心肌病的基因缺陷、感染和自身免疫等因素首先导致心脏骨架结构的损害和扩大，进而发生心肌细胞的变性、坏死和纤维化过程，最后导致心功能降低和心力衰竭。

Objective: To determine the mitochondrial DNA contents in the peripheral blood cells of patients with mitochondrial myopathy/encephalomyopathy.

目的：了解线粒体肌病/脑肌病患者外周血细胞线粒体DNA的拷贝数量有无异常。

ABSTRACT Objective: To determine the mitochondrial DNA contents in the peripheral blood cells of patients with mitochondrial myopathy/encephalomyopathy.

摘 要 目的：了解线粒体肌病/脑肌病患者外周血细胞线粒体DNA的拷贝数量有无异常。

The up-regulation of the expression of MMP-9 perhaps takes part in the accrementition and reconstitution of mesenchymal fibers (Ⅰ-type collagen dominates in mesenchymal, IOD ratio ofⅠ/Ⅲchanged). MMP-9 can facilitate inflammatory cell infiltration, aggravate the development of CAM.

2MMP-9的增高可能参与了骨骼肌间质纤维增生及其构成的改变(Ⅰ和Ⅲ型增多，Ⅰ型胶原与Ⅲ型胶原比值增高)，诱导炎性细胞浸润，加重慢性酒精中毒性肌病的发生发展。

In addition, the genotype-phenotype and race relationship study is growing more and more noticeable because HCM is not only a genetically and phenotypically heterogeneous disease but also a disease has racial difference. However, most of the knowledge is derived from studies in Caucasian patients, little is known in Chinese patients with HCM.

国外学者对上述基因突变的分子遗传学和临床研究显示这些突变与肥厚型心肌病的临床表现密切相关，因而研究其基因型及临床表型关系具有重要的诊断意义。

Comparing with the genetic myopathy, alcoholic myopathy is the only treatable muscle disease, and it has the certain reference value to research the other metabolic myopathy by the studying of the cytes and molecular level of CAM.

国外学者在肌营养不良症和包涵体肌病的研究中发现，一氧化氮合酶(Nitric oxide synthase，NOS)与氧化应激可诱导肌萎缩的发生，且二者具有一定的相关性。

Our findings support the hypothesis that there is a shared molecular etiology of different cardiomyopathic phenotypes.

我们的发现支持如是假设——心肌病的不同表型有一个共同的分子病因。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐