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肌氨酸尿

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Urinary microalbumin was determined with immunoturbidimetry, urinary NacetylD-glucosaminidase,βDgalactosidase(GAL and glycyl proline dipeptidyl aminopeptidase were determined with rate, urinary creatinine was determined with Jaffe rate.

对127例糖尿病患者,采用免疫透射比浊法检测尿mA,速率法检测N乙酰βD氨基葡萄糖苷酶、βD半乳糖苷酶、甘氨酰脯氨酸二肽氨基肽酶,Jaffe速率法测尿肌酐。

The rats were killed 10 weeks later to determine the weight of femur, bone mineral density and bone gla protein, alkaline phosphatase, calcium and phosphonium in serum and Ca, hydroxyproline and creatinine in urine.

实验10 w后处死大鼠,测定股骨重量、骨密度,检测血清骨钙素、碱性磷酸酶、钙、磷,同时检测尿钙、羟脯氨酸及肌酐等指标。

Results: The changes following hydrocortisone intervention of rats could be identified by PCA, and the kidney deficiency syndrome rats entered a state of "hyperfunction", involving a series of changes in metabolic pathway and metabolic network. The response integral area of lactic acid (δ 1.37) increased, indicating the accumulation of metabolites of lactic acid. The amount of dimethylamine (δ 2.72) also increased, indicating that the disorder of kidney function was related to kidney-deficiency syndrome. The response of creatinine (δ 3.87), asparaginic acid (δ 2.83), taurine (δ 3.44, 3.28), and hippurate (δ 7.84, 7.56, 7.64, 3.97) all decreased significantly, indicating that the hydrocortisone might cause adrenal cortex excretion injury. The response integral area of succinate (δ 2.41) and citric acid (δ 2.53, 2.68) decreased, which was usually caused by disorder of the mitochondrial function.

结果:PCA方法处理肾虚证和空白对照大鼠尿液数据显示,两组大鼠的数据可以在得分图实现分类,与对照组比较肾虚组大鼠由于氢化可的松诱导,大鼠机体进入一个过消耗后衰弱的状态,相关代谢发生显著变化,乳酸(δ 1.37)代谢发生堆积;二甲胺(δ 2.72)的含量增加,提示肾虚与肾功能异常是密切相关的;天冬氨酸(δ 2.83),牛磺酸(δ 3.44, 3.25),马尿酸(δ 7.84, 7.56, 7.64, 3.97),肌氨酸(δ 3.87)等的相对积分面积明显下降,这预示糖皮质激素可能引起了肾上腺皮质分泌功能的损害;琥珀酸(δ 2.41)和柠檬酸(δ 2.53, 2.68)是三羧酸循环能量代谢及糖酵解的中间产物,其含量的降低,通常是由于线粒体功能紊乱所引起。

The results show that the hyperthyroidism group has elevated levels of choline, glucose and declined levels of VLDL, LDL, cholesterol, lactate, glycoprotein and alanine in serum samples relative to the healthy group. In urine samples, the hyperthyroidism group show increased levels of glucose, citrate, taurine and creatinine as well as decreased levels of hippurate, trimethylamine-N-oxide, formate and succinate.

结果表明,甲亢组血清中的胆碱、葡萄糖和三甲胺等物质的含量升高,而VLDL,LDL和胆固醇等脂质以及乳酸、糖蛋白和丙氨酸等代谢物的含量下降;甲亢组尿液中的葡萄糖、柠檬酸、牛磺酸以及肌氨酸等代谢物的含量升高,而马尿酸、TMAO、甲酸和琥珀酸等代谢物的含量下降。

In order to understand the mechanisms of livial in prevetion of bone loss in patients with premeture ovarin failure.12 cases pstients were treated with livial for two months.Then fasting urinary calcium creatinine ratio、 hydroxyproline creatinine natio、 Serum akaline phosphotase、 estradio(E2)、 Calcitonin、 bone gla-protein and interleukin-6(IL-6) were determined for these patients before and after treatment.

本文通过给12例卵巢早衰患者利维爱用药2个月,并于给药前后分别测定空腹尿钙与肌酐、羟脯氨酸与肌酐比值以及血清碱性磷酸酶、雌二醇(E2)、骨钙素、降钙素和白细胞介素-6(IL-6)的水平,以探讨Livial防止卵巢早衰患者骨量丢失的作用机制。

Demineralise Whey*, Vegetable Oils, Skimmed Milk Powder*, Lactose, Dietary Fibres (Galacto-oligosaccharides*, Polyfructose), Fish Oil, Potassium Citrate, Calcium Chloride, Calcium Carbonate, Sodium Citrate, Magnesium Chloride, Vitamin C, L-arginine, Emulsifier, Taurine, Iron Sulphate, Vitamin E, Citidine 5'-monophosphate, Zinc Sulphate, Adenosine 5'-monophosphate, Uridine 5'-monophosphate, Inosine 5'-monophosphate, Niacin, Guanosine 5'-monophosphate, Folic Acid, Copper Sulphate, Vitamin a, Vitamin B12, Pantothenic Acid, Biotin, Beta-carotene, Vitamin D3, Thiamin, Vitamin B6, Manganese Sulphate, Potassium Iodide, Vitamin K1, Sodium Selenite.

无矿物质乳清*,植物油,脱脂奶粉*,乳糖,膳食纤维(半乳糖寡糖*,多聚果糖),鱼油,柠檬酸钾,氯化钙,碳酸钙,柠檬酸钠,镁,氯,维生素C,L -精氨酸,乳化剂,牛磺酸,硫酸亚铁,维生素E,Citidine 5'-磷酸,硫酸锌,腺苷5'-磷酸尿苷5'-磷酸肌苷5'-磷酸,烟酸,5'-鸟苷磷酸,叶酸酸,硫酸铜,维生素A,维生素B12,维生素B3,维生素H,β-胡萝卜素,维生素D3,硫胺素,维生素B6,硫酸锰,碘化钾,维生素K1,亚硒酸钠。

Estimated CCr with Cockcroft and Gault's method is useful, easy to use, and suggested as a good tool for the CCr measurement by some authors.

而用Cockcroft及Gault的估算方法则较简单方便,而且有少部份外国学者建议其可用来替代24小时尿液测定肌氨酸廓清率。

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