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Hirayama disease should be considered for young patient,especially male patient,with asymmetrical amyasthenia and amyotrophy in the hand and forearm.Hirayama disease can be diagnosed if MR abnormalities of the lower cervical dural sac and spinal cord are seen in a fully flexed position.

当遇到青少年出现手及前臂不对称的肌无力和萎缩而无感觉障碍时,应首先考虑有平山病的可能,可进一步行屈颈MR检查,出现下颈髓及其硬膜囊的特征性表现可确诊。

Methods 16 patients who were diagnosed as myasthenia gravis with initial head and neck symptoms were determined by a pure tone audiometer and acoustic immitance measurement and then the acoustic reflex was reexamined 30 min after injection of Neostigminum sulfate 0.5~1?

对以头颈部和五官症状为首发症状而到我科初诊的16例重症肌无力患者进行纯音测听和声导抗检测,并在肌肉注射甲基硫酸新斯的明0.5~1.0?mg,30?min后复查声反射。检测用0.5、1.0、2.0和4.0?kHz的纯音作同侧和对侧刺激,比较用药前后有无声反射及其阈值、振幅变化、有无衰减等。

Objective To study the clinical feature of myasthenia gravisonset after thymectomy,and relationships between thymoma and MG.

目的 分析胸腺瘤术后发生的重症肌无力患者的临床特点,进一步认识胸腺瘤与MG的关系。

Atrophy and weakness of the limbs, paresthesia, and neuropathic pain result in the functional impairment of daily living and ambulation disability. Thus, in addition to pharmacological treatment, aggressive rehabilitation intervention is essential to improve the patient's functional independence of daily living and life quality.

而在药物治疗的同时,肌无力、感觉异常及神经性疼痛所影响的基本生活功能性及步行能力的障碍,更需要积极的复健治疗,以增进日常生活独立性并提升生活品质,使病患得到更完整、更全面的治疗。

We report the case of a congenital myasthenic syndrome due to a mutation in AGRN, the gene encoding agrin, an extracellular matrix molecule released by the nerve and critical for formation of the neuromuscular junction.

我们报告了一例由于AGRN集聚蛋白编码基因)突变导致的先天性肌无力综合征,AGRN是一种由神经释放的细胞外基质分子并对神经肌肉接头的形成起重要作用。

objective: to investigate diagnosis and treatment choice of detrusor hypoactivity with impaired contractile function on voiding function in benign prostatic hyperplasia.methods:the clinical date of 48 bph patients with dhic were analyzed,including clinical diagnosis,urodynamic parameters,treatment and follow-ups.results:37 patients with detrusor instability and over 40 cmh2o bladder pressure were treated successfully by turp.the time of indwelling suprapubic punctural cystostomy cathter was(1~8)weeks.11cases without di and under 40 cmh2o bladder pressure were treated by suprapubic punctural cystostomy,accepted the test of urodynamics after(1~3)months.7 cases with di were treated successfully by turp,4 cases without di were indwelled suprapubic punctural cystostomy cathter all life.conclusion:dhic worsens the voiding function of the patients with bph,and the test of urodynamic is helpful to diagnose and could provide more convinced evidences for treatment of patients.

分析膀胱过度充盈所致逼尿肌损伤,引起膀胱逼尿肌收缩无力良性前列腺增生48例患者的临床资料,包括诊断,尿动力学检查,治疗及随访结果。结果:37例经尿流动力学检查,诱发存在逼尿肌不稳定,伴膀胱内压达40 cmh2o以上,采取turp,术后留置膀胱造瘘管(1~8)周后全部拔除,排尿通畅。11膀胱内压始终未达到40 cmh2o,且在膀胱注水充盈过程中无逼尿肌不稳定出现,行膀胱造瘘后出院,(1~3)个月后经尿动力学检查复查膀胱逼尿肌收缩力,其中7例膀胱逼尿肌收缩功能有恢复,行经尿道前列腺汽化电切术治愈;剩余4例膀胱逼尿肌收缩功能几乎无任何改善。长期留置膀胱造瘘治疗。结论:良性前列腺增生导致膀胱过度充盈所致逼尿肌损伤,引起膀胱逼尿肌收缩无力患者,术前应用尿流动力学检查对膀胱逼尿肌损伤程度进行认真分析,可进行有针对性的治疗。

Based on the newly proposed nomograph, patients both with obstructed and unobstructed cases can be diagnosed accurately. Also, those patients with weak detrusor, where the bladder can not provide enough power to micturate regularly, can also be identified with this new nomograph, which again can not be diagnosed with the Abrams-Griffiths nomogram.

根据我们计算和实验的结果,我们得知在没有阻塞的尿道流场内,摩擦损失是影响压力损失最主要的因素;而在轻微阻塞的尿道流场内,磨差损失及阻塞段几何外型改变,面积改变的能量损失都影响很大;而在较为严重的阻塞情况下,阻塞段的外型,最小截面积等影响能量损失甚为巨大,另外我们根据计算的结果发展出一个无因次参数图,我们选用了Reynolds number和来做参数,结果发现这样不仅可以把阻塞和未阻塞的病例分清,甚至能判断逼尿肌无力等症状。

Meticulous postoperative care and sufficient breath support should be carried out for high risk patients to diminish the incidence and mortality rate of postoperative myasthenic crisis.

术后给予高危患者严密的监测和充分的呼吸支持,有助于降低重症肌无力危象的发生率和死亡率,同时应充分重视气道护理和感染的防治。

Parasitizing specially in the cytoplasma of small granular hemocytes, RLOs formed an inclusion body in host cell, in which, RLOs propagated in mass and caused the host cell swelling and disorganizing, subsequently released and infected other target histocytes, resulted in the arising of such symptoms as debility and shivering of limbs, etc..

RLOs专一性寄生于小颗粒细胞的胞质内,以包涵体的形式生长繁殖,随着RLOs的快速增殖,包涵体内RLOs数目显著增多,且多呈圆形,包涵体极度膨胀,将细胞核压向周边,最终细胞被胀破,释放出RLOs再去侵染其它组织和器官,造成颤抖、肌无力等全身症状。

The myasthenia survival condition also is striking Zhu Changqing innermost feelings, when she viewed that some children due to be taunted by the schoolmate for "curls upwards the foot" to leave school, henceforth to keep silent; more people painfully flinch in the area of study and employment. Then she made a silent decision in her heart: She cannot only consider about herself, must handle some matters for this community which including her.

肌无力者的生存状况也敲打着朱常青的内心,当看到有的孩子因为被同学嘲讽为&翘脚&哭着退学、从此不言不语,更多的人在读书、就业的一关关前痛苦地退缩,她心中默默地下了决心:不能独善其身,要为自己所属的这个群体做些事情。

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