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In rat hippocampal slices, TBS induced phosphorylation of p21-activated kinase and its downstream effecter cofilin, signaling proteins that enable actin filament growth.

在鼠海马切片中,短暂快速脉冲刺激导致蛋白激酶21的磷酸化,在它的下游区产生了cofilin ,一种能使肌动蛋白丝生长的信号蛋白。

They were unaware of the extrarenal and renal factors separate from GFR that might influence BUN and reported that serum creatinine concentration was not a reliable indicator of kidney damage.22 Morris subsequently developed, produced, and sold a reduced-protein diet, KD, for dogs with renal failure.

没有被注意到的肾外和肾脏因素被肾丝球体过滤率做分离,其有可能影响血中尿素氮,报告也指出血清肌酸酐浓度并不是一个可靠测量肾脏损害的指标。22 Morris随后为了肾衰竭的狗开发出降低蛋白质的饮食、进而生产、分装做销售。

This phenomenon explains the broken balance between monomeric and filamentous actin.Whether the balance between monomeric and filamentous actin is a precondition to microsporidian glow or a pathological process still needs to study.

肌动蛋白纤丝的解聚合和再聚合平衡被打破是家蚕微孢子虫在家蚕中肠细胞中生长发育的前提还是微孢子虫感染后的病理反应还需进一步的研究。

Microtubules are shown in green, actin is in red and mitotic chromosomes are colored blue.

绿色的是微丝,红色为肌动蛋白,蓝色的染色体正处于赤道板。

The first method adopts different kind microbes to ferment buckwheatextraction. The method can increase DCI and its derivation content in buckwheat seed solution, while itreduces sugar content in extraction. The research adopts Saccharomyces cerevisia, Mucor, Bacterium coli, Torulopsis apicola, Aspergillus oryzae Bacillus subtilis, Candida mycoderma, Black mold that inoculate inbuckwheat extraction. Determine content change of various compotent with tracing.

方法一采用不同种类微生物发酵荞麦提取物,增加荞麦籽粒水溶液中D-手性肌醇及其衍生物的含量,同时减少提取物中总糖含量,本研究采用酿酒酵母、毛霉、大肠杆菌、蜜蜂生球拟酵母、米曲霉、枯草芽孢杆菌、解酯假丝酵母、黑曲霉接种于荞麦提取物中进行培养,并跟踪测定提取物中各种成分的含量变化。

Signalling through CXCR4 mediates actin polymerization and pseudopodia formation in cells, and induces chemotactic and migration to target organs. In addition, CXCR4-SDF-1 axis can promote tumor angiogenesis and growth.

CXCR4在肿瘤组织中的表达明显高于正常组织,而肿瘤常见转移部位均为CXCR4的配体基质细胞衍生因子-1(stromal cell derived factor-1,SDF-1)表达丰富的器官,SDF-1与CXCR4结合后可使细胞肌动蛋白丝聚合,形成伪足,从而定向诱导肿瘤细胞迁移到特定的靶器官;此外,CXCR4与其配体SDF-1相互作用可以促进局部新生血管作用,利于肿瘤生长。

By randomly single-pass sequencing from 5'-end of muscle cDNA library and liver cDNA library from Silkie Fowl, 16600 ESTs of muscle tissue which are more than 100bp and uncontamination and 17733 ESTs of liver tissue which are more than 100bp and uncontamination have been obtained.

利用大规模DNA序列测定方法,对丝毛乌骨鸡胸肌组织和肝脏组织的2个cDNA文库在5'端进行了大规模的单向单次的随机测序,得到了肌肉组织的16600条大于100bp高质量无污染的ESTs和肝脏组织的17733条大于100bp高质量无污染的ESTs。

Morphologically similar lesions from 26 patients (mean age, 62 y; range, 46 to 88 y; male/female ratio, 10/16) were retrieved from surgical pathology and consult files. Clinical and endoscopic data were obtained, and immunohistochemistry for S-100 protein, glial fibrillary acidic protein, neurofilament protein, epithelial membrane antigen, claudin-1, CD34, smooth muscle actin, and KIT was performed. The findings were compared with those in mucosal biopsies of 5 submucosal neurofibromas from NF1 patients.

我们从外科病理和档案库里调取了26例病变形态相似的病例(患者平均年龄62岁,范围:46至88岁,男女比例:10/16),得到了他们的临床及内窥镜资料,并给它们都做了S-100蛋白、胶质纤维酸性蛋白、神经丝蛋白、上皮膜抗原、闭合蛋白-1(claudin-1)、CD34、平滑肌肌动蛋白和KIT的免疫组化,所得的结果都与5例NF1患者粘膜下神经纤维瘤的粘膜活检的结果相比较。

The injured gill cells had a different ultrastructure, with endoplasmic reticulum dilated and vesiculated, mitochondrial cristaes partially disintegrated, gill fibre cuticles denatured and dropped. The ultrastructural damages to hepatopancreatic cells were characterized by the decrease of microvilli, swelling and breaking up of mitochondria, expansion of endoplasmic reticulum, disruption and vacuolization of nucleus, tumefaction of nuclear membrane and increase of lipid droplets. As for the toxicological changes of myocardial cells, the mitochondria were swelling, having a lot of vacuolus and disintegrating, while the myofibrils were irregular with endoplasmic reticulum dissolved.

鳃细胞的损害表现为鳃丝水肿,细胞器溶解,角质层变薄,线粒体、内质网的肿胀、解体;肝胰脏细胞的主要损害特征为肝管微绒毛减少,线粒体水肿解体,内质网扩张,细胞核空泡化,核膜水肿和脂肪滴增加;心脏细胞的毒理变化为线粒体内嵴肿胀、瓦解,肌原纤维不规则,内质网溶解。

In conclusion, continuous exposure to tetracaine at small concentrations delayed neurite growth, reduced the number of filopodia, and decreased actin content.

结论,连续暴露在低浓度地卡因可延缓神经突生长,降低丝伪足的数量和减少神经突肌蛋白数量。

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