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After 6 to 8 weeks behavioral test, electrophysiologic test, muscle weight measurement of flexor carpi ulnaxis and abductor digiti minimi manus, and ultrastructural observation were carried out.

对120只Wistar大鼠在上臂皮神经人水平不同程度切断尺神经(分别切断1/6,1/3,1/2,2/3及全部),术后6~8周观察大鼠的行为变化,尺神经电生理变化,尺侧腕屈及小指展湿重比及细胞超微结构的改变。

Forearm flexor origin from the medial epicondyle was exposed to allow tunneling of the long head tendon underneath the flexor origin.

方法切断胸大在肱骨的止点,在肱骨结节间沟顶端切断肱二头长头腱,然后向远端分离,显露至长头腱桡骨结节止点处,将前臂屈起点从肱骨内髁下方分离;将肱二头长头腱从前臂屈下方深面穿过,反折后穿过胸大止点,调整好张力再返回远端编结缝合。

Results These two patients were confirmed to suffer from DMD. They were characterized by typical features of DMD including typical clinical manifestations, increased serum enzymes, EMG presenting myogenic impairment, HE staining presentation belonging to DMD, negative dystrophin in brother, and inconstantly positive on the sarcolemma of sister. Furthermore, no deletion or duplication was found in the 1-79 exons of dystrophin gene. The suffering brother and sister carried the same maternal X chromosome.

结果 兄妹二人符合DMD诊断,具有典型的DMD临床表现,酸激酶、酸激酶同工酶、乳酸脱氢酶、羟丁酸脱氢酶和谷草转氨酶的水平均显著高于正常值,电图呈源性损害,肉HE染色符合DMD,男患者的抗萎缩蛋白表达阴性,女患者的少量纤维仍可见不连续膜阳性,两患者抗萎缩蛋白基因的1~79号外显子未见缺失和重复突变,女患者与男患者携带相同的母源性X染色体。

Intravoneous injection of 0.5mg/kgBW jingsongling cause the 60 minutesrelaxation of goat gastric motor.The effects of jingsongling on the gastric motor ofgoat is major of effects of α2 -adrenoceptor agonist,as well as that of α1 -adrenoceptor agonist,the effects of α1 -adrenoceptor agonist concentrate at thecardic and pylorus;the function of α2 -adrenoceptor exit widely at cardic,pylorus,rumen,reticulum,omasum and abomasum,the function at different part is not the same.The lowestdose of jingsonglinginhibiting the amplitude and frequency of the gastricmyoelectric is 0.01mg/kgBW;the influence of jingsonglingto the gastricmotility of goat is dose-dependent,and the amplitude regain after the frequency ofgastric myoelectriv wave.When the goat revived,the gastric motor function is notreach the level of the normal;the major reason ofjingsongling cause the goat gastricrelaxation is the amplitude renew slowly.The intravoneous injection ofjingsonglingfirst,after 5 minutes,intravoneous injection the antagonist,the effect of prazosin and idazoxan mixed is best,which can fast reversal of theinhibition of jingsongling on the gastric motor of goat,the effects of idazoxan isgood,and the prazosin block the effection of jingsongling is better than that ofxylazine,especially at cardia and pylorus.When intravoneous injection of0.5mg/kgBW idazoxan and/or prazosin only,the amplitude of gastric myoelectric ingoat increases at a certain degree,but the frequency is not changed.

静脉注射0.5mk/kgBW的静松灵引起山羊胃蠕动弛缓长达60分钟;静脉注射0.5mg/kgBW的静松灵对山羊胃蠕动机能的影响是以α2肾上腺素受体作用为主的,兼有α1肾上腺素受体的作用,而且静松灵的α1肾上腺素受体的作用主要集中在幽门和贲门;α2肾上腺素受体的作用广泛存在于贲门、瘤胃、网胃、瓣胃、皱胃和幽门中,不同部位间有功能上的差异;静注0.01mg/kgBW的静松灵是对山羊的贲门、瘤胃、网胃、瓣胃、皱胃和幽门的电波频率和振幅均产生影响的最低剂量;静注一定剂量的静松灵对山羊胃蠕动的抑制作用与剂量呈相关性;而且山羊胃电波振幅的恢复比电波频率的恢复慢;苏醒时山羊的胃蠕动机能尚未恢复到正常状态;静松灵引起山羊胃弛缓的主要原因是由于胃电波的振幅恢复慢;静注0.5mg/kgBW的静松灵,5分钟后静注0.5mg/kgBW的拮抗剂时,咪唑克生+哌唑嗪的作用最好,能迅速地逆转静松灵对山羊胃蠕动的抑制作用,咪唑克生也有很强的拮抗作用,而哌唑嗪对静松灵的拮抗效果好于对隆朋的拮抗;单独静注0.5mg/kgBW的咪唑克生和/或哌唑嗪时,山羊的瘤胃、网胃、瓣胃、皱胃、贲门和幽门的电波振幅有一定程度的增强,而电波频率未见变化。

There were very significant differences about the values of MP, MPF and AEMG among the motion muscles, but there was no significant difference about the singals of MF slope, MPF slope and AEMG slope. In patients group there were significant differences about the values of MF, AEMG, AEMG slope of motion limb between paretic side and non-paretic side. There were also significant differences about the values of MPF slope between paretic side of the patients and left side of the health. But there was no significant difference about other parameters in groups or among groups. Compared the activity muscles of four groups, there were significant difference about the values of AEMG and MPF among initiative muscles, antagonistic muscles and co-contraction muscles. There were very significant differences about the values of MF and MPF among co-contraction muscles, but there was no significant difference between initiative muscle and antagonistic muscle.

结果:两组各活动肢体间比较除AEMG斜率均值外MF、MPFAEMG及MF斜率及MPF斜率均值差异无显著性意义;各活动肉间比较MF、MPF、AEMG均值差异有显著性意义,而MF斜率、MPF斜率及AEMG斜率均值无显著性差异;活动肢体因素四个水平间比较除偏瘫组患侧与健侧之间的MF和AEMG、AEMG斜率均值和偏瘫组患侧与正常组左侧的MPF斜率均值有显著性差异外,其余参数在偏瘫组与正常组组内、组间的差异无显著性差异;活动肉因素4组肉间对比:主动与拮抗以及协同AEMG、MPF差异有显著性,协同之间MF、MPF差异有非常显著性,拮抗与协同差异无显著性。

According to a completely randomized block design, 54 pigs (Larger White×Landrace) with an average weight of 53kg were assigned to three treatments. The diets contained the same amino acid pattern (TDLys : TDMet : TDThr : TDTrp=100 : 34.6 : 71.7 : 19.2) and digestibile energy levelDE 3200 kcalkg^(-1 with different crude protein levels (CP 10%, 18% and 26%, respectively). The trial lasted for 67 days before slaughter, and longissimus dorsi, psoas major, semaitendinosus, semimembranosus, arm triceps, glutaeus medius, the area, diameter and density of the muscle fibers were measured.

采用完全随机区组设计,54头53kg大×长生长猪随机分为3个处理(每处理3个重复),饲喂等氨基酸(TDLys:TDMet:TDThr:TDTrp=100:34.6:71.7:19.2)、等消化能DE 3200kcalkg^(-1和不同蛋白水平(CP 10%,18%和26%)的3种饲粮,饲喂期67d之后屠宰采样,测背最长、腰大、半腱、半膜、臂三头、臀中纤维面积、直径和密度。

Masses that ranged in size from 1.0 to 20.0 cm (median 3.0 cm, mean 3.9 cm) were reported in specific muscles of the lower extremities (including vastus lateralis, adductor muscle, and groin muscles, n=39; gastrocnemius, n=22), followed by the trunk, neck (mentalis, n=8; sternocleidomastoid muscle, n=8), and upper extremity.

肿块大小1.0cm至20.0cm(中位大小3.0cm,平均大小3.9cm),大部分位于下肢特定群内(包括:股外侧、内收、腹股沟处骨骼,39例;腓肠,22例),其次位于躯干、颈部(颏,8例;胸锁乳突,8例)和上肢。

Methods Employing cholera toxin B-subunit combined horseradish peroxidase retrograde tracing technique and cholera toxin B-subunit combined colloid goldretrograde tracing with calcitonin gene-related peptideimmunohistochemical double-labeled staining technique,the innervation of musculus sacrococcygeus ventralis medialisin rats was studied.

大鼠骶尾腹内侧又称荐尾腹侧中(musculus sacrococcygeus ventralis medialis)或屈尾短,是位于盆腔后壁、骶椎前方的一对梭形肉,属尾群,因其功能似乎仅为屈尾,故至今尚未引起人们的注意,而与该位置关系较密切的会阴因在某些运动神经元疾患时仍可保持其正常生理功能而一直受到神经工作者的关注,尤其是近年来有诸多文献报道了会阴的神经支配、相关神经元的细胞构筑、神经递质和神经调质的分布以及纤维联系特点[1~10],藉以探讨运动神经元疾病的神经病理学。

We compared the effect of the number of weekly repetitions of a static stretching program on the flexibility, hamstring tightness and electromyographic activity of the hamstring and of the triceps surae muscles. Thirty-one healthy subjects with hamstring tightness, defined as the inability to perform total knee extension, and shortened triceps surae, defined by a tibiotarsal angle wider than 90 degrees during trunk flexion, were divided into three groups: G1 performed the stretching exercises once a week; G2, three times a week, and G3, five times a week.

我们比较每周重复静态牵张方案的次数对灵活性、腘绳紧张以及腘绳与小腿三头电灵敏度的影响。31例腘绳紧张的健康受试者(腘绳紧张为无法进行全膝伸展和小腿三头缩短(躯干弯曲时胫附的角度大于90度))被分为3组:G1组,进行每周一次的牵张训练;G2组,进行每周三次的牵张训练;G3组,进行每周五次的牵张训练。

In group A, the left musculocutaneous nerve was transected to make the model of biceps brachii denervation and anastomosed to its proximal end 6 weeks later; In group B, the musculocutaneous nerve was transected and the distal end was coapted to the purely motor medial pectoral nerve immediately and the musculocutaneous nerve was separated from the medial pectoral nerve, and reanastomosed to its proximal end 6 weeks later.

随机分为两组( n =8):皮神经延期修复组,单纯剪断左侧皮神经,造成肱二头失神经支配模型,6 周后行皮神经修复;神经移位寄养二期皮神经修复组,剪断左侧皮神经后即刻将胸内侧神经分支的近端移位寄养于皮神经的远端,6 周后结束寄养关系行二期神经修复术。

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