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肉瘤

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They are very similar to osteosarcomas but unlike osteosarcomas, they do not produce the bony substance, osteoid.

他们非常相似,但不同的骨肉瘤肉瘤,他们不产生骨的物质,骨质。

Results Lung carcinosarcoma had the characteristics of both lung cancer and sarcoma.

结果 癌肉瘤的CT表现显示具有肺癌和肉瘤的双重特征。

Methods Nuclear β-catenin expression was detected by immunohistochemistry in 77 lesions with desmoid-type fibromatosis and 171 other spindle cell lesions, including superficial fibrmoatosis (n=18), nodular fasciitis (n=36), keloid (n=16), scar (n=10), granulation tissue (n=9), synovial sarcoma (n=38), neufibroma (n=13), solitary fibrous tumor (n=12), gastrointestinal stromal tumor (n=10), low-grade myxofibrosarcoma (n=3), low-grade fibromyxoid sarcoma (n=3), and smooth muscle tumor (n=10). In addition, the immunohistochemical expressions of ER-α, ER-β and Ki-67 were examined in all of the lesions with desmoid-type fibromatosis. The nuclear immunohistochemical staining for nuclear βcatenin and ER-β was graded as high level (≥25% of cells), low level (5%-25%) or none.

采用免疫组织化学染色法检测77例韧带样型纤维瘤病和171例其它良、恶性梭形细胞病变(包括结节性筋膜炎36例、浅部纤维瘤病11例、瘢痕疙瘩16例、增生性瘢痕10例、肉芽组织9例、滑膜肉瘤38例、神经纤维瘤13例、孤立性纤维性肿瘤12例、胃肠间质肿瘤10例、低度恶性黏液纤维肉瘤3例、低度恶性纤维黏液样肉瘤3例及平滑肌肿瘤10例)组织中β-catenin核阳性的表达,同时检测韧带样型纤维瘤病中ER-α、ER-β和Ki-67的表达。

PPO gene was not detected in the multiple myelome、 malignant fibrous histiocytoma 、malignant lymphoma、malignant neurosarcoma、solitary plasmacytoma of bone、primitive neuroectodermal tumors、lipoma、 osteosarcoma and sarcoenchondroma.

PPO基因在多发性骨髓瘤、恶性纤维组织细胞瘤、恶性淋巴瘤、恶性神经肉瘤、孤立性浆细胞肉瘤、原始神经外胚瘤、脂肪瘤、骨及软骨肉瘤等肿瘤中没有表达。在骨巨细胞瘤中有微弱表达。

RT-PCR detection of SYT-SSX mRNA can be used in formalin-fixed, paraffin-embedded tissues as a sensitive and specific technique in the diagnosis and differential diagnosis of synovial sarcoma. 2. The SYT-SSX fusion type is related to histological type and cell proliferative activity of synovial sarcoma. 3. Some characteristic sequence motifs flank genomic breakpoints of chromosomal translocation of synovial sarcoma, including Alu sequences, Translin recognition sequences, topoisomerase Ⅱ recognition sites and palindromic sequences, which may be associated with chromosomal translocation of synovial sarcoma.

1、RT-PCR技术检测SYT-SSX mRNA表达可用于福尔马林固定、石蜡包埋组织,敏感性和特异性高,可用于滑膜肉瘤诊断和鉴别诊断。2、SYT-SSX融合基因类型与滑膜肉瘤组织学分型及细胞增殖活性相关。3、滑膜肉瘤染色体易位断裂点旁存在一些特征性序列,包括Alu序列、易位素识别序列、拓扑异构酶Ⅱ识别位点、回文序列等,可能与其染色体易位发生机制有关。

In part Ⅲ of this ariticle,The authors report some other neoplasms and precancerous changes, and they are adenoma of stomach, hemangiofibroma of ovary,carcinoma of Fallopian tube, osteo-petrosis,cholangiocarcinoma, polyps, leukoplakia,atypical hyperplasia, papillar...

这些肿瘤是鼻咽癌、副鼻窦癌、鼻腔癌、食管癌、卵巢癌,淋巴细胞性白血病、白色肉瘸、淋巴肉瘤,外阴癌、纤维肉瘤、原发性肝癌、小肠癌、结肠癌、乳腺癌,圆形细胞肉瘤、纤维瘤、脂肪瘤、马立克氏病、肾癌、畸胎瘤、膀胱乳头状瘤和口腔癌。

Abstract] objective to discuss radiological findings of parosteal osteosarcoma on emphasis combined with clinical pathology and literature.methods 4 cases of parosteal osteosarcoma proved by operation and pathology were analyzed retrospectively.results female was 3 cases,male was 1 case,average age was 30.5 years old,these tumors were arised on posterior border of distal femur and popliteal cavity,presented as lobular dense ossified mass,defined lesion.one case had villose margin.a thin narrow lucent zone separated the mass from the cortex at two cases.one case underwent angiography,there was no malignant feature.conclusion parosteal osteosarcoma may be divided into low-grade type and high-grade type.radiological manifestations of early stage possess character,early diagnosis conduces to establish rational treating plan and evaluate prognosis.

目的 结合临床病理学特征和文献资料,重点讨论皮质旁骨肉瘤的x线特征。方法收集经手术、病理证实的皮质旁骨肉瘤病例4例,对其进行回顾性分析。结果 4例患者女3例,男1例,平均年龄30.5岁,肿瘤均发生于股骨远端后侧和腘窝处,表现为分叶状致密骨化肿块,边界清晰,其中1例边缘呈绒毛状改变,2例有细窄透亮带与骨皮质相隔,1例行血管造影,未见血管池等恶性征象。结论皮质旁骨肉瘤分为低度恶性和高度恶性两种,早期影像学表现有特征性,早期诊断有助于制订相应的治疗方案和评估预后。

A minority of retroperitoneal liposarcomas may, either at the time of initial diagnosis or at the time of local recurrence, contain nodule of non-lipogenic sarcomatous elements.

少数腹膜后脂肪肉瘤可以在初次诊断或局部复发时发现局灶区非脂肪肉瘤肉瘤成分。

Sarcomatoid carcinoma is defined as a tumor having both sarcomatous and carcinoma components. Hepatic sarcomatoid carcinomas are rare and often arise from hepatocellular carcinoma or cholangiocarcinoma.

肉瘤性腺癌系指肿瘤同时表现出肉瘤及腺癌之特徵,肝脏的类肉瘤性腺癌是很少见的而且常常是由肝细胞癌或胆管癌变形而来。

Most of these non-lipogenic elements appear like fibrosarcoma or MFH, and often display features of high grade sarcoma. Sometimes, the sarcomatous elements are that of a low grade fibrosarcoma (consisting exclusively of spindled cells).

大部分非脂肪肉瘤成分镜下很像纤维肉瘤或恶性纤维组织细胞瘤,并且通常显示的是高级别肉瘤的特征。

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客人们在卡罗利娜·埃凯家里,举止就文雅一些,因为卡罗利娜的母亲治家很严厉。

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