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肉瘤

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Adenocarcinoma is the most common type, followed by sarcomas such as fiborsarcoma and chondrosarcoma.

腺癌是最常见的种类,其次是肉瘤,例如纤维肉瘤和软骨肉瘤

There were 36 males and 40 females,with the average age of 47.7 years.36 patients presented with sciatica and perineal numbness,11 patients had painless mass and the other 20 were identified due to other causes.Among 67 benign neurogenic tumors,54 were originated from S1-S3 nerves,3 from S4-S5 nerves and 11 from the presacral space without caudal involvement.Giant cell tumor was found in 60 patients,which included 24 males and 36 females,with an average age of 32 years.Upper sacrum(S1-S2) was involved firstly.There were 56 patients(average,37.7 years) diagnosed as other primary benign bone tumors,which included 24 cases of teratomas,epidermoid cyst or dermoid cyst.Other malignant tumors,including chondrosarcoma (17),Ewing′s sarcoma/PNET(14),multiple myeloma(12),lymphoma(6) and osteosarcoma(6) were found in 64 patients.

其中脊索瘤95例,男62例,女33例,平均年龄55.7岁,骶尾区疼痛是主要症状(82例),半数以上患者伴有坐骨神经痛,肿瘤多先累及低位骶骨(S3~S5);神经源性肿瘤76例,男36例,女40例,平均年龄47.7岁,神经纤维瘤43例,神经鞘瘤24例,恶性神经鞘瘤9例,主诉多为坐骨神经痛、会阴部麻木(36例)和无痛性包块(11例),20例患者为查体或其他原因检查时发现,67例骶骨良性神经源性肿瘤起源于S3以上神经者54例,起源于S3以下神经者3例,发生于骶前未累及骶管者10例;骨巨细胞瘤60例,男24例,女36例,平均年龄32岁,腰骶尾部不适(37例)、坐骨神经痛(21例)是主要的临床表现,肿瘤多先累及上位骶骨(S1~S2);骶骨其他原发良性肿瘤及瘤样病变56例,包括畸胎瘤、皮样囊肿、表皮样囊肿共24例;其他原发恶性肿瘤64例,包括软骨肉瘤17例,尤文肉瘤14例,多发性骨髓瘤12例,成骨肉瘤6例等。

Our findings demonstrate that in conjunction with clinical and radiographic findings, immunohistochemical evaluation with a panel of D2-40, EMA, brachyury, and GFAP is most useful in distinguishing chordoid meningioma from chordoid glioma, skeletal myxoid chondrosarcoma, extraskeletal myxoid chondrosarcoma, chordoma, low-grade chondrosarcoma, and enchondroma. A lack of strong, diffuse S100 reactivity may also be useful in excluding chordoid meningioma.

我们的结果表明,结合临床和影像学资料,D2-40、EMA、brachyury和GFAP这样一个免疫标记组合就能很好地鉴别脊索样脑膜瘤和脊索样胶质瘤、骨的黏液样软骨肉瘤、骨外的黏液样软骨肉瘤、脊索瘤、低级别软骨肉瘤、内生性软骨瘤。S100染色不强烈、不弥漫也有助于排除脊索样脑膜瘤的诊断。

EMA was the most effective antibody for differentiating chordoid meningioma from skeletal myxoid chondrosarcoma, low-grade chondrosarcoma, and enchondroma, whereas D2-40 was the most effective antibody for differentiating chordoid meningioma from extraskeletal myxoid chondrosarcoma and chordoma.

EMA是鉴别脊索样脑膜瘤和骨的黏液样软骨肉瘤、低级别软骨肉瘤、内生性软骨瘤最有效的抗体,而D2-40则是鉴别脊索样脑膜瘤和骨外黏液样软骨肉瘤、脊索瘤最有效的抗体。

Spindle cell sarcomas, such as malignant fibrous histocytoma, fibrosarcoma, and leiomyosarcoma.

梭形细胞肉瘤,如恶性纤维组织细胞瘤,纤维肉瘤,平滑肌肉瘤

Such as malignant tumors, mostly to cancer, such as gastric cancer, liver cancer, colon cancer, but also can be seen in the sarcoma as fibrosarcoma, leiomyosarcoma and so on.

此类肿瘤多为恶性肿瘤,以癌居多,如胃癌、肝癌、结肠癌,也可见于肉瘤如纤维肉瘤、平滑肌肉瘤等。

Methods From January 1998, sixteen patients suffed from osteosarcoma(6 cases), chondrosarcoma(3 cases), gaint cell tumor(6 cases) and fibrosarcoma(1 case) arising from femur(5 cases), tibia(5 cases), humerus(3 cases), fibula(2 cases), radius(1 case).

1998年1月起,我院对16例肢体恶性骨肿瘤(按病理骨肉瘤6例,软骨肉瘤3例,骨巨细胞瘤6例,纤维肉瘤1例;按部位股骨5例,胫骨5例,肱骨3例,腓骨2例,桡骨1例)行骨肿瘤局部切除术及术中放疗加植骨。

The sarcomatoid areas generally show features of MFH, fibrosarcoma, or undifferentiated spindle cell sarcoma.

肉瘤样区域可具有恶性纤维组织细胞瘤(malignant fibrohistiocytoma,MFH)、纤维肉瘤或未分化梭形细胞肉瘤的一般特征。

Dedifferentiated liposarcoma, occurring in up to 10% of well differentiated liposarcoma cases, has similar histologic features to that of undifferentiated high-grade pleomorphic sarcoma; the former develops in a background of atypical lipomatous tumors/well differentiated liposarcoma, whereas the latter shows no specific line of differentiation.

去分化脂肪肉瘤占高分化脂肪肉瘤比例达10%,其形态特征与未分化高级别多形性肉瘤有相似之处;前者发生在不典型脂肪肿瘤/高分化脂肪肉瘤的背景上,后者无特定分化方向。

Very rarely, features of high grade osteosarcoma, leiomyosarcoma, chondrosarcoma, rhabdomyosarcoma and malignant peripheral nerve sheath tumor are found.

罕见的情况下可以找见高级别骨肉瘤、平滑肌肉瘤、软骨肉瘤、横纹肌肉瘤和恶性外周神经鞘膜瘤的特征。

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