联基

Then the cyclocarbonylation of propargylic alcohols under the catalysis of Pd 〓 with CuBr〓 and BQ was studied. Due to the high activity the yields of -α-bromoalkylidene-β-lactones were lower than that of -α-chloroalkylidene-β-lactones while the coupling reaction of -α-bromoalkylidene-β-1actones (i. e. Sonogashira and Suzuki coupling reaction) was quite smooth to afford the products in high yields.

接着我们研究了炔丙醇在Pd〓-CuBr〓-BQ催化体系下的羰基插入环化反应，由于-α-溴代亚烷基-β-内酯环化合物的活性高于-α-氯代亚烷基-β-内酯环化合物，导致反应收率偏低，而同样基于此原因，-α-溴代亚烷基-β-内酯环化合物的偶联反应进行得很顺利，而且收率很高。

Biaryl substituted pyrazole compounds are sodium channel blockers useful for the treatment of pain and other conditions.

联芳基取代吡唑化合物为钠通道阻滞剂，用于治疗疼痛和其它病症。

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

The in vitro degradation of the crosslinked composites formed by unsaturated polyphosphoester N-vinyl pyrrolidone and β-tricalcium phosphate was investigated and the surface morphology of degradation sample was imaged by scanning electron microscopy.

研究了不饱和聚磷酸酯、N-乙烯基吡咯烷酮与β-磷酸钙交联复合体系的体外降解过程，并用扫描电镜观察了降解一定时间后试样表面的形貌结构。

The in vitro degradation of the crosslinked composites formed by unsaturated polyphosphoester、N-vinyl pyrrolidone and β-tricalcium phosphate was investigated and the surface morphology of dagradation sample was imaged by scanning electron microscopy.

研究了不饱和聚磷酸酯、N-乙烯基吡咯烷酮与β-磷酸钙交联复合体系的体外降解过程，并用扫描电镜观察了降解一定时间后试样表面的形貌结构。

Ridging Hedta(superscript 3-) anions between Bi atoms and Pr atoms result into a novel infinite 3D network structure.

i-Pr间通过配阴离子Hedta(上标 3-)中4个羧基的桥联作用构建配合物的3D结构。

The obtained terephthalaldhydic acid semicarbazone has such advantages as simple process and high purity (above 99% after post treatment), and can be used as standard in enzymoimmunoassay of semicarbazide.

本发明成功合成了呋喃西林代谢物氨基脲的衍生物氨基脲缩对醛基苯甲酸，合成步骤简洁，经过后处理，纯度高达99％以上，完全可以用作标准品，为以后人们对氨基脲的酶联免疫检测研究提供了方便的途径，可以满足国内对其研究的需要。

The segments 〓 and 〓 were coupled via Cadiot-Chodkiewcz reaction to afford the intermediate 〓. After the silyl protective groups were removed by TBAF from 〓, we accomplished the stereoselective total synthesis of the target molecule-(11S, 16S)- Oplopandiol Acetate〓.

通过中间体化合物〓和〓的Cadiot-Chodkiewiza炔炔偶联反应得到了中间体化合物〓，再用TBAF脱除保护基完成了目标化合物〓的首次全合成，确证其绝对构型为11S、16S。

Effects of steric hindrance and conformation on the properties of the polymer were investigated.

通过在聚合物中引入芴和联苯的结构以及在PPV单元上引入不同链长的侧基等研究了聚合物的几何构型以及位阻等因素对材料性质的影响。

A high molecular weight polyisobutenyl succinimide dispersant with high nitrogen content and good thermal and oxidative stabilities was developed.

采用氯化烃化工艺和后偶联反应技术开发了一种氮含量高、热稳定性和氧化稳定性好的高相对分子质量的聚异丁烯基丁二酰亚胺分散剂。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失