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All wear a tightly wrapped dhoti with the end falling from the waist to fill a narrow space between the legs. They wear a three-pronged golden tiara, with elongated halo behind and ring-lets of black hair falling behind the ears and over the shoulder, as in some of the other figures associated with the Tibetan period at Dunhuang.

全都穿了裹得很紧的腰布,腰部的末端从腰部垂下位於两腿之间的部分,他们像吐蕃时期敦煌画中常见的诸像一样,戴著金色通天冠,黑色卷发从耳后垂到肩上,头后面的光环向四周发著光。

The raw data was processed by using axial, coronal and double oblique multi-planar reformation; Images obtained were graded in terms of quality with a 5-point scale(5=excellent, 4=good, 3=fair, 2=poor, and 1=nondiagnostic). In grading image quality at axial MPR, The radiologic specialists focused on the subarcuate fossa, tendon of tensor tympani, facial recess, vestibular aqueduct and pyramidal eminence, In grading image quality at coronal MPR, attention was given to the scute, crista transversa, fenestra cochleae, lateral malleal ligament and snake eyes signature of cranial nerve, In the grading of the image quality at double oblique MPR, the radiologic specialists concentrated on the malleus, incus, stirrup bone, upper bony semicircular and aquaeductus fallopii, and then to implement statistical analysis. In order to choose the minimum tube current values and the maximum pitch that can satisfy the diagnosis request, image quality of axial, coronal and double oblique reformation images was compared with different tube current groups. 15 ears of volunteers were used to test the validity with the scanning parameter. Subsequently noise, MTF and dose length product were measured by phantoms in different tube current and pitch, the parameters obtained were compared and taken into statistics analysis.

扫描模式使用临床常用的颞骨螺旋扫描方式:管电压120 kV,准直宽度20×0.6 mm,视野200 mm,重建矩阵512×512,旋转时间1 s/r,重建层厚0.6 mm,重建间隔0.3 mm,分别改变管电流(380、300、200、160、120和80 mA)和螺距(0.8、1.0和1.2)进行扫描和重建,然后对颞骨进行横断面、冠状面和双斜面多平面重组,于重组后的横断层面图像上选取弓形下窝、鼓膜张肌腱、面神经隐窝、前庭导水管和锥隆起5个解剖结构,冠状面重组图像上选取盾板、横嵴、蜗窗、面神经的蛇眼征和锤骨外侧韧带5个解剖结构,双斜面重组图像上选取锤骨、砧骨、镫骨、上骨半规管和面神经管5个解剖结构,在双盲的情况下由放射学专家分别对各管电流和螺距下扫描的重组图像进行评分,随后进行统计学处理,从中筛选出满足诊断要求的最低管电流值和最大的螺距,分别采用患者25例(15耳)用该管电流值和螺距验证其可行性;然后利用模体分别测试各管电流和螺距下的图像的空间分辨率、噪声及其剂量长度积,并对测试所得参数数值进行比较和统计学处理。

Morphological and flourescent changes were assessed using confocal microscopy in whole-mount organ of Corti preparations. Results (1) After the animals were exposed to broadband noise at 122 dB SPL in 4 h/day for 2 days, both apoptosis and necrosis appeared in OHCs. The single strand DNA in apoptotic OHCs were observed both in guinea pigs and mice.(2) In normal OHCs, EndoG was distributed outside of nuclei. EndoG translocated from outside to inside of the nuclei in both apoptotic and necrotic OHCs following noise exposure.(3) The MNNG cochlear perfusion and noise exposure both caused the transloctation of AIF from the mitochondria to the nuclei. The translocation of AIF took place in both apoptotic and necrotic OHCs.

结果 (1)暴露于120 dB SPL的白噪声环境中每天4小时,连续2天后引起豚鼠和小鼠耳蜗外毛细胞凋亡时,其细胞核内产生ssDNA,而在正常细胞内没有三ssDNA;(2)在正常情况下,EndoG分布于耳蜗毛细胞的细胞核外,在暴露于上述噪声后发生凋亡和坏死的豚鼠耳蜗外毛细胞中,EndoG从细胞核外转移到细胞核内,细胞核中的EndoG显著增加;(3)豚鼠耳蜗外淋巴灌流烷化剂MNNG后发生耳蜗外毛细胞凋亡和坏死,在凋亡和坏死的耳蜗外毛细胞中,AIF自线粒体转移到细胞核,其变化与噪声损伤引起耳蜗外毛细胞凋亡和坏死时一致。

From the perfusion experiments with isolated rabbit heart and vessels were obtained the follow- ing results:(1)Potassium antimony tartrate produced depression of the isolated rabbit heart,and this depressant action became more marked when the pH of the solution was raised from the original value of 5.4 to that of 7.2;(2)At the same pH levels,the cardiac action of the potassium salt was slightly stronger than that of the corresponding sodium salt;(3)The slight vase-dilator effect of potass- ium anti...

从离体器官的灌注实验得到下列结果:(1)酒石酸锑钾对离体兎心有抑制作用,将其pH 从5.4调整到7.2时,作用亦随以增加。(2)在相同 pH 时,酒石酸锑钾的心臓抑制作用较酒石酸锑钠略强。(3)酒石酸锑钾对离体兎耳血管的轻微扩张作用,系由于该药溶液的微酸性反应,当将药液 pH 调整至7后即无作用。(4)对于离体兎肺血管则不问 pH 为4.8或7,均产生轻微的血管收缩作用。

For it is rubor after damaging to the closing soft tissue, getting swollen, getting hot aching and model of functiolaesa these bed solicit and there is no fracture,no skin damaged, we designed the corresponding experiment, namely the law of hot board causes little mouse\'s painful experiment of threshold of pain; Freun\'s complete adjuvant caused the swollen experiment of big mouse\'s foot;The xylene caused the swollen experiment of little mouse\'s ear; Invigorating blood circulation silt experiment that changes the sex that the rheology appearance examines the blood and flows with the blood; Useing the high performance liquid chromatography-electrochemistry Detected monoamine neurotransmitters transmitter in the brain and serum; the experiment of immunohistochemistry measured the proto-oncogene C-FOS expresses.

针对闭合性软组织损伤后的红、肿、热、痛及功能障碍的典型临床体征,加上无骨折、无皮肤破损的特点,我们设计了相应的实验,即热板法致小鼠疼痛的痛阈实验;福氏完全佐剂(Freun\'s complete adjuvant,FCA)致大鼠足肿实验;二甲苯致小鼠耳肿实验;用血流变仪测血液流变性的活血化瘀实验;运用高效液相色谱—电化学(high performance liquid chromatography-electrochemistry Detection HPLC-ECD)法测量大脑及血清中单胺类神经递质的实验以及免疫组织化学法检测原癌基因C-FOS蛋白产物表达的实验。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan (the average body weight was 25~30 kg)were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P<001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P<001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P<001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P<001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系,探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只,平均体重25~30 kg。随机分为3组:正常对照组10只,模型组10只(球囊内膜剥脱加高胆固醇饮食),治疗组10只(球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d)。结果兔髂动脉造影、血管病理图像分析检测结果:①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比,各组之间有显著性差异(P<001)。②免疫组化分析:模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组(P<001);复方丹参滴丸组MMP2、MMP9的表达低于模型组,而TIMP1、TIMP2的表达高于模型组;TIMP1/MMP2、TIMP2/MMP9明显增加,差异有显著性(P<001)。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896,P<001)。结论 MMP和TIMP在再狭窄形成中起重要作用;复方丹参滴丸能够明显抑制血管损伤后的内膜增生,可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生,而减少内膜的增生。

The experiments may contribute not only to investigating the mechanism of interaction between ldiotype and anti -idiotype T cells by which immune network are up-regulated, but also to analysing the suppressive effect of anti -idiotypic T cell or antibodies against the antigens on the activated T cells in the allo-responsiveness.

本课题选用小鼠耳后心肌移植模型,用同种抗原特异的活化T淋巴细胞免疫同系小鼠的方法,诱导免疫小鼠同种心肌移植物存活时间的延长,以此探讨免疫网络中独特型-抗独特型相互作用机理,着重分析在同种抗原诱导的免疫应答中,抗独特型T细胞和抗活化T淋巴细胞抗原抗体对同种免疫反应的抑制作用。

Ten patients with temporal bone fracture and trauma of ear,whose CT scan of temporal bone showed that Malleoincudal joint irregular shape in the axial view and incudostapedial joint dislocation in the coronal view,were included in this study,Virtual endoscopy showed Malleoincudal joint separation,incudostapedial joint dislocation and interruption,ossicular chain disruptio...

虚拟耳镜示锤砧关节分离,砧镫关节脱位,听骨链中断。手术经颞线下开放上鼓室,保留完整的外耳道后上壁,充分暴露上、后鼓室和听骨链,检查并行听骨链成形术。结果:砧骨长脚骨折1耳,将砧骨改型后行锤-镫连接术;锤砧和砧镫关节脱位6耳,砧骨完全脱落3耳,行砧骨复位双关节固定术。10耳均行上鼓室进路鼓室探查术,术后语频听力平均提高25~50dB。结论:完壁式上鼓室进路鼓室探查术治疗外伤性听骨链中断疗效满意。

Based on it, further experiment was carried out to investigate the topical use of papaverine for the polential role of hearing protection in surgery. Fifteen purebred Zelanian big rabbits were derided into 5 groups, each respectively, as the group with phenylephrine (group 1), with papaverine and phenylephrine (group 2), with physiological saline solution. Auditory brainstem sponse latency and distortion product otoacoustic emissions were measured at different times.

将15只(30耳)大白兔暴露面听神经血管复合体后,分为局部应用去氧肾上腺素组(实验组1,10耳)、局部注射罂粟碱后再放置去氧肾上腺素组(实验组2,10耳)和局部放置生理盐水组(对照组,10耳),分别用听性脑干反应和畸变产物耳声发射观察三组兔听功能的变化。

The verb "shanah," which originally meant "to repeat," acquired in post-Biblical Hebrew the special force of "to teach" and "to learn" that which was not transmitted in writing but only orally; the development of connotation being due to the fact that the retention of teachings handed down by word of mouth was possible only by frequent recitation.

动词& shanah ,&最初指的是&重复&,收购后的圣经希伯来文的特殊部队&教&和&学习&这是不以书面形式转交只是口头;发展的内涵是由於这样的事实,即保留的教导下来的口耳相传是可能只有通过频繁的朗诵。

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