耐药的

Objective To study the mechanism of drug resistance of APL to ATRA and the methods of reversion.

目的 揭示急性早幼粒细胞白血病产生维甲酸耐药的机制，探讨耐药性逆转的方法。

Arsenous acid solution is an effective drug for the treatment of relaps ed APL which was resi stant to tretinoin.

亚砷酸是治疗对维A酸耐药的复发急性早幼粒细胞白血病的有效药物，并相对比较安全。

To judge the relationship between the expression of mdrl gene and chemotherapeutic drug resistance in breast cancer.

判断乳腺癌mdr1基因的表达与化疗药物耐药的相互关系。

When induced by adriamycin, the expression was enhanced and Fas mainly existed in cytochylema.

Fas表达水平的变化可能是体内癌细胞耐药的机理之一。

The change of outer membrane permeability in Mar strains of Escherichia coli plays an important role in multiple drug resistance.

外膜 通透性的改变是大肠杆菌产生多重耐药的机制之一。

Dr. Gane: When we are talking about re-treating patients with established antiviral resistance, I think we will really look at approaches.

Gane博士：谈到对已确定发生耐药的患者进行复治的问题，我想我们的确需要注重方法。

The following data were obtained and compared between resistance and responder: white blood cell,neutrophil,hemoglobulin,C-reactive protein,erythrocyte sedimentation rate,albumin,and lactate dehydrogenase.Male patients with decreased albumin may be related with resistance,but they could not be good predictors of resistance.

川崎病患儿发生IVIG耐药的可能危险因素有外周血白细胞、中性粒细胞比例、血红蛋白、C反应蛋白、血沉、血浆白蛋白、乳酸脱氢酶等，分析结果提示血浆白蛋白降低及男性可能与IVIG不敏感川崎病有关，但仅此两项指标尚不能预测IVIG不敏感川崎病的发生。

Among 558 isolates, 65 （11.6 ~）isolates produced hyperproduction AmpC β-lactamases, 135 （24.2 ~） iso- lates produced ESBLs,and 28（5.0%）produced both enzymes.

对阴沟肠杆菌进行耐药性监测及去阻遏持续高产AmpC酶和ESBLs检测，能较好了解该地区细菌耐药的现状，为当地临床医生抗生素的使用提供合理建议。

Methods: The immunohistochemical staining technique was employed to measure the expression levels of Edg-2, Edg-4, and Edg-7 protein in human epithelial ovarian neoplasma.

并分析LPA受体在人卵巢癌组织中的表达状况及其与顺铂化疗耐药的关系。

Three years ago, the Food and Drug Administration approed the drug Ketek, lauding it as the first of a new class of antimicrobial agents that circument antibiotic resistance.

三年前，食物及药物管理局批准了药物泰利霉素，声称它是第一个新的可以避免耐药的抗生素。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。