耐药的

A new kind of paper shell plain detonator with GTG primary explosive is introduced.

文章介绍了 GTG型火雷管技术，对该雷管的装药结构、GTG 起爆药和 KG点火药的极限装药量、耐压性、相容性和可靠性等方面的结果进行了全面的介绍。

In this topic we detected the expression level of SDF-1,CXCR4,VEGF of the above two malignant hematological tumors as well as their relations to the tumor cell"s characters of drug resistance and infiltration etc, and then elucidated the change of the microenviroment" on the occurrence and development of hematologic tumor. This topic may provide some theoretical and clinical proofs for finding out some new therapeusis to the above two malignant hematological tumors.

本课题旨在通过研究急性白血病和恶性淋巴瘤患者SDF-1、CXCR4、VEGF的表达水平及其与肿瘤细胞迁移、耐药、浸润的关系，阐明骨髓造血微环境和恶性淋巴瘤局部病变微环境的改变在上述血液肿瘤发生发展中的作用及其与血管新生的联系，为从新的角度探索白血病、淋巴瘤的治疗方法提供理论及临床依据。

Abstract］ Objective: To investigate the effect of the mycobacteriophage D29 liposome-coating liquid in the mice infected by multi-drug resistant tubercle bacillus, as a new method in treating multi-drug resistant tuberculosis.

［摘要］目的：研究D29分枝杆菌噬菌体脂质体包被液对耐多药结核杆菌感染小鼠的治疗效果，探寻治疗耐多药结核病的新方法。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质，三羟异黄酮的作用机制主要包括：①抑制蛋白酪氨酸激酶活性，可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递，导致癌细胞增殖受抑；②弱雌激素作用：可通过与体内雌激素受体结合，并可增加细胞内性激素结合球蛋白的合成，增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性；③拓扑酶Ⅰ和Ⅱ抑制剂，抑制细胞活性；④上调细胞周期性负性调节因子P21WAF1/CIP1的表达，使之负性调节因子作用增强；⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长；⑥其他：抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

Treating multi-drug resistant tuberous caseous pneumonia with drug-containing gel application by fiberoptic brcnchoscope is effective and safe.

含药凝胶介入治疗耐多药结核性干酪性肺炎是一种有效和安全的新方法。

The antiablation of silicone rubber liner can be improved both by changing the structure of unvulcanized rubber and adding antiablative fillers,and the bond strength between propellant charge and the liner would be increased largely by coating the primer liquid on the charg...

硅橡胶包覆层中填料的粒径对硅橡胶的补强效果十分重要；可从改变生胶结构、添加耐烧蚀填料两方面来改善硅橡胶包覆层的耐烧蚀性；在推进剂药柱表面上涂覆底涂液可以大幅提高硅橡胶包覆层与推进剂的粘接强度。

85 And 119486/79. They are a novel type of antibiotic having both the wide antibacterial spectrum and high safety of penicillin and cephem antibiotics belonging to beta -lactam antibiotics, as well as the potent antibacterial activity and high beta -lactamase stability of carbapenem antibiotics.Sodium-(5R, 6S)-6-[-1-hydroxyethyl]-7-oxo-3- [-2-tetrahydrofuryl]-4-thia-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylate 5/2 hydrate (faropenem sodium, hereinafter referred to as compound 1) is currently used as an oral drug for various infectious diseases and is reported to show potent antibacterial activity against not only methicillin-sensitive Staphylococcus aureus, Streptococcus pyrogenes and Streptococcus pneumoniae but also gram-positive bacteria for which conventional beta -lactam drugs have proved ineffective such as penicillin-resistant pneumococci, oral staphylococci and enterococci, also showing a wide antibacterial spectrum covering gram-negative bacteria such as Haemophilus influenzae and anaerobic bacteria such as the genus Bacteroides, which activity is due to its novel skeleton penem ring (Kagaku Ryoho no Ryoiki The Field of Chemotherapy, Vol.

他们是一种新型的抗生素都具有广泛的抗菌谱和高度的安全青霉素和cephem抗生素，属于β-内酰胺类抗生素，以及作为强大的抗菌活性和高β-内酰胺酶稳定的碳青霉烯类antibiotics.sodium -（ 5 R ， 6 S ）-6 -[ - 1 -羟乙基] - 7 -氧- 3 - [ - 2 - t etrahydrofuryl] - 4 -硫杂- 1 -氮杂双环[ 3 。2.0]庚- 2 -节能- 2 -羧酸5 / 2水合物（法罗培南钠，以下简称为化合物1 ）是目前用来作为口服药物，为各种传染病和报道，以显示强大的抗菌活性，不仅对甲氧敏感的金黄色葡萄球菌，链球菌pyrogenes和肺炎链球菌，但也克阳性菌为常规β-内酰胺类药物已证明无效，如青霉素耐药pneumococci ，口腔葡萄球菌和肠球菌，也显示出广泛的抗菌谱，包括革兰阴性菌如流感嗜血杆菌和厌氧菌如属杆菌，这活动是由于其新颖的骨架青霉烯环（（化学ryoho没有ryoiki领域的化疗），第13卷，第10号，第74-80 ， 1997年）。

Shun Ho by agents NIKKISO EIKO quantitative pump, BB for the main models, mainly used in water treatment plus drugs, plus drugs, such as manufacturing process, due to stable performance, the effect of the fine, Platts clients affirmation for satisfy domestic customers for various types of pumping requirements and provide a full range of services, one after another deputy Japan SEIKOW acid pumped magnetic and corrosion-resistant blower and other new products, but also Deputy German technical cooperation with Taiwan SERA automatic foam polymer drug equipment, Germany Verder pump hose pneumatic double diaphragm pump, stainless steel magnetic pump, Italy nova / SIDEX uniaxial screw pump, CSFinox pneumatic piston pump food-grade health-pumped, the United States standard barrel with electric pneumatic pump, the introduction of a wider range of new products, provide customers more choices.

顺贺所代理的NIKKISO EIKO 定量泵，BB为主力机种，主要运用于水处理加药，制程加药等，由于性能稳定，效果优良，普获客户肯定，为了满足国内客户对于各类型泵浦需求及提供全方位的服务，陆续代理日本SEIKOW耐酸碱磁力泵浦及耐腐蚀送风机等新产品，同时也代理德国SERA与台湾技术合作高分子自动泡药设备，德国VERDER软管式泵气动双隔膜泵浦，不锈钢磁力泵浦，意大利新星/SIDEX单轴螺旋泵，CSFinox气动柱塞式泵浦食品级卫生泵浦，美国标准电动气动桶用泵浦，引进更广泛的新产品，提供客户更多的选择。

Identification of extensive phenotypic information to 6 pare cultures and detection of the mol% G+C ratio of the DNA to representative strains, showed that the examined bacteria belonged to a new morphovar of Acinetobacter junii, and was designated as Acinetobacter junii Morphovar Ⅰ. In addition, serotype, antibiotic sensitivity and pathogenicity of isolates were studied, the results showed that the 6 strains have the same K-antigen and O-antigen, there arc no obvious differences in sensitivity and resistance to used 37 antimicrobial agents between strains, and have strong pathogenicity to experimental stone bonder and Bastard halibut.

经对6株纯培养菌在形态特征、理化特性等方面较系统的表观分类学指征鉴定及代表菌株DNA中G+C mol%的测定，表明为琼氏不动杆菌的一个新形态型并定名为琼氏不动杆菌形态型Ⅰ(Acinetobacter junii morphovar Ⅰ)；同时，对该菌进行了血清型、对抗菌类药物的敏感性及致病作用等方面的试验，初步表明此6株菌具有同种的表面及同种的菌体抗原，对供试37种抗菌类药物在不同菌株间的敏感及耐药无明显差异，对供试石鲽及牙鲆均具有较强的致病作用。

They continue to be effective at second- and even third-line therapy; however, alternative treatments are needed for patients who are or have become refractory to these agents or whose remissions are shorter with each course of therapy.METHODS.

他们持续地成为有效的二线甚至三线药物；然而对于对这些药物耐药或者对于每种治疗方法的缓解期都更短的患者来说，二选一的治疗是必要的。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！