耐药的

An added benefit is that it's effective in people who are resistant to lamivudine.

一个附加的好处是，它的有效的人谁是拉米夫定耐药。

To probe the mechanism of reducing the drug tolerance of salmonellosis to aminoglycosides antibiotics, the influence of the Chinese traditional compound preparation "LN" on drug-resistance gene aph(3')-Ⅱα-mRNA of salmonellosis was studied.

通过研究中药复方制剂连黄对沙门氏菌耐药基因aph(3')-Ⅱα的mRNA表达水平的影响，从而深入探讨连黄降低沙门氏菌对氨基糖苷类药物的耐药性作用机理。

The activity of the drug-resistance gene aph(3')-Ⅱα-mRNA decreased after the reaction with the Chinese traditional compound preparation "LN", and then reduced the drug tolerance of salmonellosis to aminoglycosides antibiotics.

结果表明，连黄作用后的沙门氏菌耐药基因叩aph(3')-Ⅱα的mRNA表达量降低，进而降低了沙门氏菌对氨基糖苷类药物的耐药性。

Cisplatin is one of the widely used therapeutic agents and acts both as a cytotoxic agent and as a radiation sensitizer. The acquired resistance to cisplatin often leads to the failure of treatment.

顺铂是治疗鼻咽癌的最常用抗癌药之一，起细胞毒性和放射增敏的双重作用，然而顺铂引起的继发耐药常导致治疗失败。

In order to find new kinds of antibacterial agents, a primary screening model has been set with the DNA gyrase B subunit as a target, and then the active compounds of positive strain were purified. From Mycobacterium phlei, we isolated a novobiocin supersensitive mutant M.phlei SS12 and a resistant ~mutant M.phlei RR11 with NTG and UV.

实验采用Mycobacteriumphlei为出发菌株，利用NTG和紫外线复合诱变得到新生霉素特异性的超敏菌株M.phleiSS12和耐药菌株M.phleiRR11，建立了以DNA回旋酶B亚基为靶点的抗结核药物的筛选模型；并应用此模型对1600株真菌和100株放线菌发酵液进行了初筛，获得了38株阳性菌，阳性率为2.4%；对阳性菌株3277的发酵液进行了提取分离，得到X1和X2两个活性化合物。

With more and more antibiotic-resistant microorganisms emerging, antibiotic abusee accelerates this process. Antibacterial peptide's mechanism against target cells is remarkably different from that of traditional antibiotics.

传统抗生素耐药菌株种类不断增多，全球抗生素的滥用加速了这一过程，抗菌肽的开发将为解决这一棘手难题提供更多的途径。

One ESBLS-producing strains was detected in Pseudomonas aeruginose,Enteric aerogenes and Citrobacter,respectively.

由于ESBLS阳性株对临床常用抗生素的耐药率远远高于ESBLS阴性株，使临床治疗面临极大的困难，必须引起临床医生和临床微生物室的重视。

The prevalence rate of NTM in Shanghai shows increased tendency.Most of NTM isolates are Group Ⅳ rapidly growing NTM.NTM shows high drug resistance to first line antituberculotic substance.

上海市NTM感染呈逐年上升趋势；感染菌种的分布以Ⅳ群快速生长的NTM为主；NTM对常用的抗结核药物呈高度耐药现象。

Objective: To study the role of anti-apoptotic protein Mcl-1 in bile salt-induced chemoresistance of hepatocellular carcinoma cells.

的：探讨抗凋亡蛋白Mcl-1在GCDA诱导的肝癌细胞耐药中的作用及其机制。

Results Among the 2,034 patients suspected with NGU, 765 were positive with various pathogens, and the positive rate was 37.6%. The positive rates of chlamydozoan, mycoplasma and mixed both infection were 384, 324, and 57 respectively. Among the 381 mycoplasma infection cases, the sensitive antibiotics were josamycine (89.76%), doxycycline (88.45%), and clarithromycine (69.55%); however, mycoplasma was not sensitive to ciprofloxacin (93.44%), erythromycin (64.31%) and cravit (56.96%).

结果 2034例可疑NGU患者检出各种病原体感染765例，阳性率37.6%，其中衣原体阳性者384例(18.9%)，支原体阳性者324例(15.9%)，混合感染者57例(2.8%)。381例支原体对10种抗生素的敏感率最高的是交沙霉素和强力霉素(89.76%、88.45%)，其次为克拉霉素(69.55%)，耐药率最高的是环丙沙星(93.44%)，其次为红霉素(64.31%)和可乐必妥(56.96%)。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐