耐药的

Methods:The minimum inhibitory concentration of the olive polyphenol against the common oral pathogenic bacterium was quantitatively determined with the agar-agar dilution method combined with the micro liquid dilution method.

选用质量控制标准菌株和临床分离的对多数抗生素耐药的菌株，采用琼脂稀释法和微量液体稀释法相结合的药敏实验方法，定量测定橄榄多酚对口腔颌面部感染常见病原菌的最低抑制浓度。

Sulfonamide anilide compound could inhibit human bladder cancer cell growth in vitro, most likely through induction of P21(superscript waf/cif1) mRNA expression and subsequent arrest of cell cycling at G1 phase.

Compound在体外能有效抑制对传统化疗耐药的人膀胱癌细胞生长，其抗肿瘤生长机制可能是通过上调P21(上标 waf/cif1)mRNA水平从而使细胞阻滞于G1期所致。

The aim of this study is to observe the corelation of GSTπ and the drug resistance of taxans.

第二部分研究，体外观测GSTπ表达与紫杉类药物耐药的关系。

Objective To observe the effect of Changweiqing oral liquid on reversal of mulitdrug resistance and the effect on concentration of DOX in tumor and normal tissue.

目的 观察中药复方肠胃清口服液对肿瘤多药耐药的逆转作用，以及对瘤组织和正常组织中化疗药物分布的影响，探讨中药增效减毒的作用机制。

Our study showed that Thurberg Fritillary Bulb could modify MDR by reverse P170, MRP, LRP′s high expression, inhibiting the active efflux pump in cell membrane. It is promising in clinical application and worth investigating in depth.

本研究发现：浙贝母散剂在无明显毒副作用情况下可以逆转急性白血病多药耐药的发生，其机制主要与逆转P170、MRP、LRP高表达，抑制细胞膜转运蛋白的外排泵功能有关，具有一定的临床应用前景。

Some drugs are showing like a five-year mutational rate as high as 70%, but other drugs showing maybe less than 5%.

一些药物5年出现变异耐药的几率为70%，而别的药物可能少于5%。

Objective :To investigate the effect and the mechanism of angiotensin-converting enzyme inhibitors on nitroglycerin to lerance.

目的：探讨血管紧张素转换酶抑制剂对硝酸甘油耐药的影响及机制。

We now need to find a way to prevent resistance from developing.

我们现在需要找到一种方法，阻止耐药的发展。

Objective:To explore clinical infectious status of imipenem-resistant Pseudomonas aeruginosa with its risk factors.

目的：探讨亚胺培南耐药的铜绿假单胞菌临床感染情况及其危险因素。

Pharmaceutical excipients were used as a vehicle of water-soluble, liposoluble and even indissolvable drugs with low toxicity and satisfactory biocompatibility. Furthermore, it provides direction and method to decrease efflux of cytotoxic drugs from the cancer cells, promote the effect of clinical therapeutic efficacy, recover the sensitivity of the cancer cells to the cytotoxic drugs, and improve the characteristics of pharmacokinetics of some drugs such as increasing the absorption of some orally drugs, decreasing the renal clearance and hepat-clearance.

此外，通过抑制P-gp的外排功能，一些药用辅料具有逆转肿瘤细胞多药耐药的作用，为临床提高抗肿瘤药物的疗效，减少肿瘤细胞对药物的外排，提高其对药物的敏感性，提供了研究方向和试验手段。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。