耐药的

The azole drugs including fluconazole target lanosterol 14α-demethylase, the product of the ERG11 gene. Ergllp is one of the enzymes in the biosynthesis of ergosterol, the major sterol of fungal membranes and an analogue of cholesterol in mammalian systems.

唑类药物外流也是导致唑类耐药的主要原因，而与之药物外流泵相关的基因有ATP结合盒转运子基因(ATP Binding Cassette Transporter)——CDR1、CDR2和主要易化子基因——MDR1、FLU1，他们的过度表达可以导致唑类耐药的发生。

Results In 585 staphylococcus, there were 406 staphylococcus aureus, which including 387 methicillin sensitive staphylococcus aureus and 19 methicillin resistant staphylococcus aureus. And there were 179 coagulase negative staphylococcus, including 20 methicillin sensitive coagulase negative staphylococcus and 159 methicillin resistant coagulase negative staphylococcus.

结果 585株葡萄球菌中，金黄色葡萄球菌406株，其中甲氧西林敏感的SA387株，甲氧西林耐药的SA19株；凝固酶阴性的葡萄球菌179株，其中甲氧西林敏感的CNS20株，甲氧西林耐药的CNS159株。

How to induce apoptosis in these never-die cell in order to cure cancer is the consistency principle of the cancer researchers.

肿瘤耐药的研究一直是肿瘤研究的热点问题，如何让这些不可死亡的肿瘤细胞发生凋亡而最终达到治愈肿瘤的目的是研究肿瘤耐药的学者们一贯的思路。

When the drug no longer effective, the resistance of the virus can be freely copied again.

当药不再发挥效用时，耐药的病毒能自由地再行复制。

Objective To investigate the inhibitive effects of RNA interference on the expression of MDR1 gene in gastric cancer BGC-823 cells.

目的 寻找逆转胃癌细胞多药耐药的有效方法。

Objective To study the relationship between P - gp gene mutation and multi - drug resistance of breast cancer.

目的研究乳腺癌中P-gp基因的突变与其多药耐药的关系。

Objective To investigate the mechanism of multidrug resistance in huma n glioma cell and the way to overcome MDR.

目的 研究胶质瘤多药耐药的发生机理及逆转方法。

Objective To study the reversion effect of dipyridsmole on multidrug resistance in gastric cancer.

目的 研究双嘧达莫对胃癌细胞多药耐药的逆转作用。

Objective To investigate the functional mechanism of Chinese drug disodium cantharidinate reversing multidrug resistance of tumor cells.

目的 观察斑蝥酸钠对多药耐药的白血病细胞(K562/AO2)细胞是否有逆转作用，并初步探讨其逆转机制。

The transfer of resistance genes was conducted by conjugation.

结论同时存在的ESBLs和AmpC酶是肺炎克雷伯菌和产酸克雷伯菌耐药的主要原因，耐药基因的转移可导致耐药性的传播扩散。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。