耐药的

However, this approach conferred the resistance to not only myelopoietic cells but also tumor cells that have invaded or metastasized into bone marrow or circulating blood for nonspecific expression of the exogenous genes.

详细骨髓造血细胞中导入耐药耐辐射基因是克服放化疗对造血系统抑制作用的有效手段，但外源基因的非特异性表达也增加了残存在血液或者侵犯至骨髓中的肿瘤细胞耐受性。

Previous studies have shown that the mechanisms of MDR involve Pgp, MRP, LRP, BCRP, GSH/GST, PKC, Topo DNA plerosis, genes related to apoptosis and changes of cellular environment (such as pH, hypoxia and temperature).

目前发现的肿瘤多药耐药机制主要涉及Pgp、MRP、LRP、BCRP、GSH/GST、PKC、TopoⅡ、DNA修复、多种凋亡相关基因和肿瘤细胞生活的内外环境变化。

Previous studies have shown that the mechanisms of MDR involve Pgp,MRP,LRP,BCRP,GSH/GST,PKC,Topo DNA plerosis,genes related to apoptosis andchanges of cellular environment (such as pH,hypoxia and temperature).

目前发现的肿瘤多药耐药机制主要涉及Pgp、MRP、LRP、BCRP、GSH/GST、PKC、TopoⅡ、DNA修复、多种凋亡相关基因和肿瘤细胞生活的内外环境变化。

There are significant association between patients′ prognosis and multidrug and drug resistance gene in uveal melanoma.

结论葡萄膜黑色素瘤多药耐药基因尤其LRP的表达与患者预后具有明显的相关性。

Results 336strains of pathogenic bacteria were separated from the urine sample of2865cases and the detectable rate was11.73%of the336separated strains the number of strains of gram negative bacilli was226,the gram positive cocci is92and the fungi is18.the positive rate of escherichia coli was the highest followed by co-agulase negative staphylococci,klebsiella pneumoniae and blue verditer pseudomonas.highest resistance to penicillins and cephalosporins was obsered.

结果 从2865份尿标本中分离出336株病原菌，检出率为11.73%。其中革兰阴性杆菌226株，革兰阳性球菌92株，真菌18株。阳性率最高的是大肠埃希菌，其次是凝固酶阴性葡萄球菌、克雷伯菌、铜绿假单胞菌。药敏结果对青霉素类、头孢类抗生素的耐药率较高。

The P-gp170 mediated MDR may be an important cause of relapsing of bladder cancer which is treated by intracavitary perfusing chemotherapy.

P-gp170介导的多药耐药是膀胱癌腔内灌注化疗失败的重要原因。

The candida albicans and candidas tropicalis was more common in clinical samples, and the positive rate of drug resistant strain against fungus increased gradually. So it is important to culture, isolate and identify the fungus from clinical samples, and do the antifungal sensitivity at the same time.

临床上酵母样真菌感染以白色念珠菌和热带念珠菌较常见；真菌耐药菌株的检出率呈上升趋势，临床上必须重视真菌的检出和药敏试验。

In order to reduce the drug resistance pathogens it is necessary to control and reduce the use of antibiotics in animal feedstuffs.

应加强控制动物饲料亚治疗抗生素的使用并严格遵守休药期，防止耐药菌株产生进而控制食源性疾病的发生。

Objective To explore factors influencing transfer of retroviral mediated multidrug resistance gene (mdr1) into human CD34+ cells.

目的 探讨逆转录病毒介导的多药耐药基因(mdr1)导入人CD34+细胞的影响因素，以提高基因转导效率。

These new fungistat solve the question of fungal resistance to drug and prevent blindly using medicine.

这些新型抗真菌药解决了真菌的耐药问题，制止了盲目的用药。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。