耐药的

In the present study, we examined the large-scale gene expression profiles with six sets of matched clinical and experimental fluconazole susceptible and resistant C. albicans strains by microarray analysis. We observed that azole resistances developed in multiple circumstances are all associated with increased expression of CDR mRNA. We also identified some common differential expressed genes and some interesting function-linked gene groups involved in drug-resistance.

利用所构建的基因芯片我们研究了共六对氟康唑敏感和耐药白念珠菌配对菌株的大规模基因表达谱，证实不同环境下产生的白念珠菌耐药性均与多药耐药基因CDR的mRNA表达增加有关，并从中鉴定了一些与药物耐受性相关的共同差异表达基因和一些有趣的功能连锁基因群。

Results Among 1 439 strains of isolated bacteria,456(31.69% were gram-positive bacteria,and 206(45.18% of which were coagulase negative Staphylococcus epidermidis,92(20.18% were coagulase positive Staphylococcus aureus...

结果1 439株细菌中，革兰阳性菌456株(31.69%)，以凝固酶阴性表皮葡萄球菌为多，达206株(45.18%)，其次为金黄色葡萄球菌92株(20.18%)；两种葡萄球菌的耐药率相似，对万古霉素耐药率均为0。

The fluorescence intensity of lobeline-treated cells was significantly higher than that of the controls, when the concentration of lobeline was more than 10 μmol/L.

洛贝林（20 μmol/L）的多药耐药逆转有效率为经典耐药逆转剂维拉帕米（20 μmol/L）的71.6%，但毒副作用显著降低。

The drug sensitive indol test result shows,imipenem,cefoperazone,the sand star bactria bears the medicine rate low(1%~3%),amino sugar glycoside and west wood,other cephalosporins.all exsits the different degree bears the medicine.

药敏试验结果显示，亚胺培南、头孢哌酮舒巴坦，沙星类的细菌耐药率低(1%~3%)，氨基糖甙类及西林类、其他头孢类等均存在不同程度的耐药。

The drug sensitive indol test result shows,imipenem,cefoperazone,the sand star bactria bears the medicine rate low(1%~3%),amino sugar glycoside and west wood,other cephalosporins

药敏试验结果显示，亚胺培南、头孢哌酮舒巴坦，沙星类的细菌耐药率低(1%~3%)，氨基糖甙类及西林类、其他头孢类等均存在不同程度的耐药。

The proportions of mono-drug resistant Tubercle bacillus have a decreasing trend year by year, but those of multi-drug resistant Tubercle bacillus still keep in a very high level.

各种抗结核药物的单药耐药情况虽有逐年下降趋势，耐多药结核杆菌维持在高水准，将给结核病的治疗带来一定的困难。

Objective: To explore the role of hypoxia-inducible factor-1α(HIF-1α) in formation of multidrug resistance induced by microenvironment and to find a new and effective molecular target on preventing and reversing chemoresistance in hepatocellular carcinoma.

目的探讨缺氧诱导因子1α(HIF-1α)在微环境诱导的肝癌多药耐药表型形成过程中的作用和地位，并为预防和逆转肝癌耐药提供有效的新的分子靶点。

The detection rates of methicillin-resistant S. aureus and penicillin-nonsusceptible S. pneumoniae were 15.9% and 84.3%, respectively. The prevalence of ESBLs-producing strains in Klebsiella pneumoniae, Escherichia coli, Serratia spp and Enterobacter cloacae were 31.2%, 46.2%, 94.8% and 16.8% respectively. The resistance rates of Hemophilus influenzae and Hemophilus parainfluenzae to ampicilin were 40% and 36% respectively.

耐甲氧西林金黄色葡萄球菌检出率为15.9%；对青霉素不敏感的肺炎链球菌（包括PISP和PRSP）检出率为84.3%；肺炎克雷伯菌、大肠埃希菌、粘质沙雷菌和阴沟肠杆菌产ESBLs的检出率分别为31.2%、46.2%、94.8%和16.8%；流感嗜血杆菌和副流感嗜血杆菌对氨苄西林的耐药率为36%和40%；铜绿假单胞菌和鲍曼复合不动杆菌对亚胺培南的耐药率分别为10.7%和13.2%。

Objective To observe the expression of multi-drug-resistant gene (MDR-1) and P-glucoprotein in malignant lymphomatous tissues and the drug-resistant mechanism of malignant lymphoma.

目的 观察多药耐药基因(MDR -1)及P -糖蛋白在恶性淋巴瘤组织中的表达情况，探讨恶性淋巴瘤的耐药机理。

We have developed a modified molecular beacon melting curve analysis for rapid screening of Ethambutol drug resistance and multi-drug MDR resistance tuberculosis.

本论文发展了一种利用改良分子信标的熔解曲线分析技术对肺结核的乙胺丁醇耐药和多药耐药突变进行快速筛查的方法。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。