耐药性

In certain cancer types, overexpression of Raf would induce drug resistance.

Raf的异常表达也影响着肿瘤细胞耐药性的产生。

A human MDRl full length cDNA probe was used to screen a pufferfish cosmid library and nine clones, which would contain the whole MDR gene family in the pufferfish genome, were finally identified. One of the cosmid clones was sequenced. Sequence analysis revealed that there would be at least three MDR homologues in the corresponding region.

其表达产物为一跨膜蛋白p-glycoprotein，通过ATP提供能量，将进入细胞内的多种物质泵出细胞外，从而使细胞对这些物质产生耐药性，多药耐药基因的功能决定了它在肿瘤化疗中的位置而使其成为基因结构、功能和表达、调控研究中的热点。

The hope is that treatment based on natural products might be less susceptible to resistance.

人们希望，基于天然物质的治疗可能会较少地产生耐药性。

Contrasting with the control strain of Shigella sonnei, the test strain could be higher antibiotics rate, and it could not be agglutinated by several anti-sera to Shigella sonnei, which were in the period of validity, but the control strain could be well agglutinated.

检测试验菌株的生化特性和对抗生素的敏感性，以及用多种批号的诊断血清进行凝集试验。结果：具有典型的宋内氏志贺菌的生化特性；与对照菌相比，有较高抗生素耐药性，对复方新诺明等多种抗生素耐药。

Objective To investigate the reversal effect of verapamil on the drug resistance of NCI-H 446 small cell lung cancer cell line induced by fractionated radiation.

目的观察维拉帕米对分次外照射引发的小细胞肺癌细胞系NCI-H446耐药性的逆转作用。

Pathogens exist as spores or other dormant forms with the absence of host plants and they have high resistance, so high concentration of methyl bromide is required while fumigating. This is likely the main reason of the environmental pollution.

土壤甲基溴熏蒸的目标在于杀死具有较高耐药性的病源物的孢子或其他休眠形式，熏蒸所需浓度高，这也是造成环境污染的原因。

Research progress of anti-tumor mechanisms of ginsenoside Rh2（G-Rh2） extracted from ginseng was expounded,and the anti-tumor activity and mechanisms of G-Rh2 were discussed on regula-ting signal access system of tumor cells,reversing abnormal differentiation and tolerance of tumor cells,reducing telomerase activity of tumor cells,strengthening immunological ability,improving anti-tumor ability ,and interdicting synthesis and metabolism of tumor cellular important components etc.

论述了从人参中提取的有效成分人参皂苷-Rh2（G-Rh2）的抗肿瘤机理的研究进展，并探讨了G-Rh2在调节肿瘤细胞信号通路系统、逆转肿瘤细胞的异常分化与耐药性、降低肿瘤细胞端粒酶活性、增强机体免疫力、提高抗肿瘤能力以及阻断肿瘤细胞某些重要成分的合成与代谢等方面的抗肿瘤活性及其作用机理。

Objective To study the feasibility of bacteria drug resistance determinated by matrix-assisted laxer desorption ionization time-of-flight mass spectrometry(MALDI-TOF-MS).

目的研究基质辅助激光解吸电离飞行时间质谱(MALDI-TOF-MS)用于检测鉴定细菌耐药性的可行性。

Objective To learn the immune level of healthy people to N. meningitidis in Shenzhen, China, to learn the population structure and genetic relationship among carried meningococci, in order to facilitate the prevention and control of meningococcal disease.

目的研究深圳市健康人群对流脑的易感性，为预防控制流脑提供依据；分析深圳市健康人群中脑膜炎奈瑟菌的带菌率及性别、年龄分布，确定人群中Nm的感染情况；研究Nm的菌群结构和遗传关系，对流脑的流行趋势作出预测，分析Nm的耐药性，指导临床和预防用药。

Background and Objective: Epigenetic silencing of the DNA repair gene, O^6-methylguanine-DNA methyltransferase, is associated with the therapeutic response to methylating agents.

背景与目的：如何预测和克服肿瘤细胞对化疗药物的耐药性，实施个体化治疗是肿瘤化疗急需解决的问题。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。