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The cultural condition of PGPR strains Temperature,pH,light,cultural method,acid or alkali producing,and salt tolerance of 9 PGPR strains isolated from Gramineous Forage were tested,the results showed that all the PGPR strains could grow in the temperature range from 5℃~45℃,and optimum temperature for 178,O-6,Dry6 strains was 35℃,for X5,173,Y5,C-6 strains was 30℃,for N4 strain was 25℃~35℃,for 86 strain was 25℃;most of PGPR strains prefered to neutral or alkaline condition,strains 178,O-6,N4 and X5 were preferable to alkali condition especially;light was beneficial to PGPR's growth;all of them produce alkali;most of PGPR strains were not sensitive to NaCl concentration;all the strains were aerobiotic bacteria.

结果表明:各供试菌株对温度的适应范围较广,在5℃~45℃范围内均能生长,178、O-6、Dry6 菌株的适宜生长温度为35℃,X5、173、Y5、C-6 菌株的适宜生长温度为30℃,N4 菌株的适宜生长温度为25℃~35℃,86 菌株的适宜生长温度为25℃;大部分菌株在中性或偏碱性的条件下生长好,特别是Dry6、N4 和X5 菌株对碱性环境适应性强,在pH 值8.0 时生长最好;光照有利于菌株的生长;绝大部分菌株在3%NaCl浓度下生长良好,在5%~7% NaCl 浓度下除173 和86 菌株外,其它菌株都能生长,即对盐份的耐受性较好,且9 个菌株均为产碱菌;除173 菌株是兼性厌氧细菌外,其它都是好氧性细菌。

The results showed: for the toxicity of two kinds of pollutants, the Cd(superscript 2+) is more poisonous that the Pd(superscript 2+). For the sensitivity to the pollutants, the P. caudatum, C cathayensi and D. japonica increase evidently in turn. The statistical analyses indicated that the single and combined toxicity effects both increase with the exposed time extended, especially for the combined toxicity (P.05), showing a marked time-effect relation. As for the single effect, ii increase prominently with Pb(superscript 2+) and Cd(superscript 2+) concentrations (P.05); But in the case of binary effect, the results showed obviously a time-effect (P.01) as well as a concentraction-effect relations.

结果表明:在同等条件下,Cd(上标 2+)对三者的致毒效应都明显强于Pb(上标 2+);3种动物中,草履虫最敏感,而圆田螺耐受能力最强;随单一毒物浓度的增大以及暴露时间的延长,两者的致毒效应都显著增大,表现出明显的浓度-效应和时间-效应关系;二者复合作用时,对3种动物的致毒效应主要表现为与二组分的浓度比例有关。

Pioneering work by Cohen and coworkers about T cell vaccination in the experimental autoimmune disease, has showed that the establishment of immune response against T cell vaccine, such as anti-idiotype T cells or anti -idiotype antibody, by the way of the upregulation of immune networks, and subsequently functional depression of autoimmune to self-antigen were made by vaccining mice or rate with the attenuated autoreactive T cells .

从研究TCV在防治自身免疫性疾病中的作用机制表明,人为的TCV免疫,建立了拮抗T细胞的免疫应答,使免疫网络产生上调作用,抑制了原有的或即将出现的相关T细胞的功能,由此推测,是否能够把同种反应性T细胞作为TCV,来建立抗同种免疫反应的内环境,诱导抗原特异性的同种免疫耐受或免疫低反应性。

The rate of clinical success, defined as cured plus improved patients, was 75% for levofloxacin and 72.8% for ciprofloxacin (95% confidence interval for the difference in the success rates,-13.27 to 8.87). Microbiologic eradication rates were also similar in both groups (75% for levofloxacin and 76.8% for ciprofloxacin; 95% CI for the difference,-8.98 to 12.58). The most common isolates were Enterococcus faecalis and E. coli . Both regimens were well tolerated, with similar rates of adverse events and of relapse by six months.

治疗成功的定义为患者的病情痊愈并且症状获得改善,结果接受levofloxacin治疗的患者成功率为75%,而接受ciprofloxacin治疗的患者则为72.8%(信赖区间为-13.27 ~ 8.87);两组的微生物根除率相当(levofloxacin组为75%,ciprofloxacin组为76.8%;信赖区间为-8.98 ~ 12.58);最常被分离出的病菌为乳酸球菌与大肠杆菌,这两种药物的耐受性都很好,副作用与六个月的复发率也都相当。

In order to discover acid-tolerant Rhizobium meliloti that can nodulate alfalfa high-effectively on acidic soil, researches were explored to isolate rhizobia from alfalfa nodules on acidic soil (pH5.2), methods based on the thesis of adaptive acid-tolerance response of the Rhizobia were adopted, six strains were isolated, which could grow on solid medium with pH4.8 steadily. In addition, the nodulation characteristics, growth curves and mean generation time under different acidity of the strains were examined.

为获得能够使紫花苜蓿在酸性土壤中高效结瘤的耐酸根瘤菌,该研究从酸性土(pH5.2)上生长的紫花苜蓿根瘤中分离到若干菌株,利用根瘤菌对酸的适应性耐受反应筛选到六株能够在pH4.8的固体培养基上稳定生长的菌株,并检测了这六株菌的结瘤特征、不同酸度下的生长曲线和平均代时。

These three internal fixations of femoral peritrochanteric fracture were differ. For example, Gamma nail is less harmful, better clinical treatment, shorter in shape and stronger in anti-hip inversion. DHS, DCS have a better treatment and are stronger in anti-hip inversion but more harmful and excessive bleeding, and HCS, which is named Minimally Invasive Surgery, is the least harmful, less bleeding, suitable for old patients and the patients of tolerance of poor operation, but poor in anti-hip inversion.

3种不同方法内固定治疗转子间骨折具有各自的特点,Gamma钉具有手术损伤小及良好的临床疗效力臂短对抗髋内翻的能力强;滑动加压鹅头钉具有良好的临床疗效及相对坚强的抗内翻能力,但手术损伤相对较大,失血量较大;空心加压螺钉固定的手术损伤最小,属于微创手术方法,可经皮完成,手术出血少,适用于高龄及手术耐受性差的患者,但抗髋内翻的能力最差。

Outcome:(1) Acute ischemic damage may induce the expression of c-fos protein in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia. And the expression level of c-fos can be up-regulated by putting blood of 12 hand Jing Points. So we think that treated by this therapy can rise the irritability of brain to resist the development of ischemia and enhance the ability to plerosis.(2) Acute ischemic damage may induce the expression of HspVO in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia.

三 结果(1)急性缺血性脑损伤可快速诱导c-fos蛋白在皮层缺血区脑组织的表达,其表达有随缺血时间延长而逐渐增多的趋势,提示脑的缺血性损伤可应激性地增强神经细胞对缺血、缺氧的耐受和适应能力,而应用井穴放血的干预治疗可明显上调缺血区皮层脑组织c-fos的表达水平,进一步增强脑组织对抗缺血性损伤的应激能力,抵抗缺血性脑损害的进一步发展。

Individuals who have a positive history but a negative skin test tolerate penicillin-class antibiotics as well as they tolerate other antibiotics, according to AAAAI literature. Although the skin test is as safe as skin testing for other allergens, a "very low rate of resensitization" will occur after skin testing and reuse of penicillin. The skin test exposes the patient to an amount of penicillin that consists of 1/5,000th of that in a typical prescription.

根据AAAAI的文献指出,有盘尼西林过敏的病历却在盘尼西林测试中出现阴性反应者,对其他抗生素有著一样的耐受特质;虽然盘尼西林皮肤测试和其他的过敏原皮肤试验具有一样的安全性,盘尼西林在经过皮肤试验及使用过后,再度产生敏感的比率却非常的低;皮肤测试中,患中会暴露在正常盘尼西林处方剂量的5000分之一。

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物,无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效,虽具有相对高的致白细胞和血小板下降的骨髓毒性,但毒副作用可耐受,已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物,但是作为一线用药仍然需要更多的临床证据来证实。

"Long-term skin cancer and actinic keratoses surveillance continue to be important,and repeated resurfacing procedures or courses of topical agents,such as fluorouracil or imiquimod, may be necessary," the researchers write."A largerstudy comparing trichloroacetic acid resurfacing for actinic keratoses reductionand nonmelanoma skin cancer prophylaxis would help validate the superiority ofthis resurfacing technique over the carbon dioxide laser andassess its cost-effectiveness compared with photodynamic therapyor imiquimod treatment." They cite improved patient compliance in the trichloroacetic-acid group, ease of performance in the outpatient setting, andsubjective measures of better tolerance as reasons this procedure is an attractive alternative to repeated courses with topicalagents or laser resurfacing.

研究者指出,长期皮肤癌和光化性角化病之监测仍是重要的,反覆的皮肤重建整形步骤、或外用制剂如fluorouracil 或 imiquimod的反覆疗程也可能是必须的;一个比较三氯醋酸皮肤重建整形以减少光化性角化病和预防非黑色素皮肤癌的大型研究,将可有助於确定其优於二氧化碳雷射的优势,以及评估其和光动力治疗或 imiquimod治疗之花费效益比比较;他们举例说,三氯醋酸组病患之遵医嘱性增加、门诊病患也容易进行、个案之测量耐受度比较佳,这些都是重复疗程时比外用药剂或雷射更有吸引力的理由。

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The split between the two groups can hardly be papered over.

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