耐受的

Of the 747 children referred, 606 (81%) received fasting blood glucose and glucose tolerance tests. Considering the logistics of obtaining these tests in children, Dr. Tilson commented,"We were really excited about this. We thought 81% showed that the program was quite effective."

在被转介的747个病患中，606位（81%）接受空腹血糖检验与葡萄糖耐受性检验；Tilson医师评论表示，考虑到如何要求儿童接受这些检验，我们对这样的结果感到很兴奋；我们认为，结果显示这样的计画是相当有效的。

Objectives:(1) to introduce immunetolerance in mice sciatic nerve allograft by intrathymic injection of allogene.(2) to compare the effect of fresh sciatic nerve allotransplantion and cold preserved sciatic nerve allotransplantation with different diameter.

研究目的：(1)探讨小鼠胸腺内注射异基因抗原在同种异体异基因坐骨神经移植免疫耐受中的作用；(2)比较不同直径的新鲜自体神经和冷冻异体神经移植的效果，探讨神经直径对神经移植效果的影响。

The approval was based on data from four double-blind, randomized trials that compared the antianginal and anti-ischemic efficacy of ivabradine with placebo, atenolol, and amlodipine in 3,222 patients. Results obtained using a standardized exercise tolerance test showed that twice-daily administration of ivabradine, 5 and 7.5 mg, significantly decreased the incidence of anginal episodes.

这项核准案是根据4项双盲随机分派试验结果，这些试验针对3，222位病患，比较Ivabradine相较于安慰剂、atenolol、及amlodipine治疗心绞痛与减少心肌缺血的效果；以标准运动耐受性测试所得到的结果显示，每天投予2次5或是7.5毫客的Ivabradine可以显著地降低心绞痛发生的次数。

The approval was based on data from four double-blind, randomized trials that compared the antianginal and anti-ischemic efficacy of ivabradine with placebo, atenolol, and amlodipine in 3,222 patients. Results obtained using a standardized exercise tolerance test showed that twice-daily administration of ivabradine, 5 and 7.5 mg, significantly decreased the incidence of anginal episodes.

这项核准案是根据4项双盲随机分派试验结果，这些试验针对3，222位病患，比较Ivabradine相较於安慰剂、atenolol、及amlodipine治疗心绞痛与减少心肌缺血的效果；以标准运动耐受性测试所得到的结果显示，每天投予2次5或是7.5毫客的Ivabradine可以显著地降低心绞痛发生的次数。

Methods The compound preparation was administered intragastrically in mice, whose spontaneous activity was observed along with their tolerance of the preparation after long-term administration. The hypnotic effect of the compound was assessed by investigating the changes in the pentobarbital sodium-induced sleeping. The compound was tested for its antiseizure effect in mice with pentetrazole-induced clonic and tonic convulsion. Diazepam was used as the standard control in all experiments.

利用光电计数法观察灌胃给予复方酸枣仁油栀子油对小鼠自发活动的影响，以及长期使用药物对小鼠耐受性的影响；利用延长戊巴比妥钠睡眠时间实验和戊巴比妥钠阈下催眠剂量实验，观察复方酸枣仁油栀子油的催眠作用；利用戊四氮诱发小鼠阵挛性、强直性惊厥观察复方酸枣仁油栀子油的抗惊厥作用；本实验用地西泮进行平行对照实验，并进行了组方设计和实验。

Because glial cell activation could also be involved in the development of opioid tolerance in rats, the authors studied the antinociceptive effects of ibudilast and morphine in different models of coadministration.

由于大鼠神经胶质细胞的激活也被证实与阿片样物质耐受性的产生有关，作者研究了异丁司特和吗啡在不同的共同给药模型中的镇痛作用。

The high prevalence of resistance to chicken sera, fimbriae F1, temperature-sensitive hemagglutinin in high pathogenic isolates suggested importance of these phenotypes in the pathogenesis of colibacillosis.

结果显示禽源大肠杆菌的致病性与其血清耐受能力、鸡红细胞MSHA菌手的表达和温度敏感性血凝素的表达呈一定的相关关系。

2The distribution of HIF-1 a and COX-2 was unequal;.(3)These findings indicate that HIF-1a and COX-2 may be two important factors in pulpal lesions and there is a significantly hypoxia condiction in inflamed pulp .(4)The increase of HIF-1 a is a possible mechanism for hypoxia preconditioning .(5)Our results suggested that pulpal fibroblasts as well as macrophages might be involved in the pathogenesis of irreversible pulpitis.

和COX一2的表达均有不同程度的变化，在牙髓炎病程中可能发挥着重要的生理和病理作用，③在牙髓炎进程中和牙髓自身修复过程中存在着缺氧环境和缺氧耐受机制，④牙髓成纤维细胞有可能与单核巨噬细胞一同参与牙髓炎的病理进程，且具有修复和免疫功能。

But the major shortcoming of these vaccines is the disability to induce cellular immunity, which is essential for eliminating the endocellular virus and breaking immunologic tolerance which exist widely in chronic hepatitis B patients.

但此类疫苗最大的缺点是不能诱导有效的细胞免疫，而细胞免疫在清除细胞内病毒，以及打破慢性乙肝患者持续的免疫耐受状态具有极其重要的作用。

The strain was inoculated to fermentive medium (pH 7.0) at the amount of 10 percent, cultured for 84 hours at 28℃ with shaking. Its antagonistic activity reached the highest level and high thermostability, pH stability and resistance to proteinase K were achieved.

以10%的接种量将该菌接种到初始pH7.0的发酵培养基中，28℃旋转培养，发酵液在84h时抗菌活性达到最高，且具有较好的热稳定性和pH稳定性，对蛋白酶K有一定的耐受性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。