耐受的

Recent elucidation of the role of central tolerance in preventing organ-specific autoimmunity has changed our concepts of self/nonself discrimination.

最近关于中枢免疫耐受在防止特异性器官自身免疫的作用的阐述改变了我们以往识别"自我"、"非我"的概念。

Objective: To study the relationship between donor blood derived allogeneic chimerism and levels of tolerance induced in the host mice, parabiosis between adult mice with H-2 complete difference was established.

摘 要：目的：探讨供体源的异基因血细胞嵌合体与受体耐受状态的关系，在不同品系的成年小鼠之间成功地建立了联体模型。

Department of Immunology, Beijing Medical University,Beijing 100083）Abstract:Objective: To study the relationship between donor blood derived allogeneic chimerism and levels of tolerance induced in the host mice, parabiosis between adult mice with H-2 complete difference was established.

摘 要：目的：探讨供体源的异基因血细胞孩子嵌合体与受体耐受状态的关系，在不同品系的成年小鼠之间成功地建立了联体模型。

In this study, we evaluated the efficacyof preanesthetic proton pump inhibitor (PPI; oral rabeprazol)use in patients receiving regular H2-antagonisttherapy for more than 4 wk. Forty-eight patients with assumedcomplete tolerance to H2 antagonists undergoing elective surgerywere recruited and randomly assigned to receive either a preanestheticPPI (rabeprazol 20 mg; n = 24) or H2-antagonist (H2 group; roxatidine75 mg; n = 24) at 9:00 pm on the day before surgery and 2 hbefore the induction of anesthesia.

本次研究，作者评价了长期规则使用氢离子拮抗剂（口服法莫替丁，疗程大于4周）治疗的病人，麻醉前使用质子泵抑制剂（ PPI ；口服雷贝拉唑）的有效性。48位择期手术的病人假设能够完全耐受氢离子拮抗剂，随机分为两组，一组接受 PPI （口服雷贝拉唑20mg ； n ＝24），另一组接受质子泵抑制剂（口服罗沙替丁75mg ； n ＝24），服药时间分别为，术前一天晚上9点和麻醉诱导前2小时。

The sry-gene chimerism of bone marrows, spleen and thymus of the receiptor, T-lymphocyte subpopulation of peripheral blood cells, ConA and LPS induced T and B cells proliferation activity tests, Mixed lymphocyte reaction between the donor and the receiptor and the third part, the incidence rate of GVHD and survival analysis were observed in mice after 8Gy TBI with MSCs and haplo-BMT treatment together.

通过观察半相合BMT联合MSCs治疗致死剂量照射小鼠后不同时间骨髓、胸腺和脾脏中供者细胞植入，外周血中的淋巴细胞亚群，ConA和LPS刺激的T、B淋巴细胞增殖，供受者及第三者混合淋巴细胞反应，急、慢性GVHD的发生率和生存分析，提示MSCs促进骨髓干细胞植入，加快T淋巴细胞增殖，促进体液免疫恢复，通过供受者免疫耐受，减少GVHD发生率，提高半相合BMT动物生存率。

The mechanism that acupuncture preconditioning induces cerebral ischemia tolerance and the reason of cerebral ischemia injuries have been studied from various angles and set up the theory of self-injurious mechanism and provide the theory foundation in preventing infarct, developing medicine and evaluating medical result.

关于针刺预处理后诱导脑缺血耐受机制及缺血性脑损伤的病因和发病机制，近年来，已从不同的角度进行了研究，并相应建立了自身破坏过程机制的假说，为防治脑梗死、开发新药和评价药物疗效提供了理论基础。

Both formulations were well tolerated and frequency of local reactions and solicited adverse events was similar among the groups.

两种配方都有很好的耐受性，而且局部反应的频率和不良事件的发生在小组中类似。

This study suggests that 250 mg/day terbinafine is an effective and well-tolerated alternative to drug therapy of cutaneous sporotrichosis in a population in which itraconazole use is not possible.

这项研究表明，用特比萘芬以250mg/天的剂量治疗禁用伊曲康唑的皮肤孢子丝菌病患者是一种有效而耐受性好的药物替代疗法。

The lower temperature reduced the tolerance-low-light of photosynthesis of sweet pepper leaves.

弱光低温或弱光适温处理下Pn的下降是非气孔限制的结果，低温降低了植株的弱光耐受性。

He said additional data on the safety and tolerability would be important.

他说，额外的数据的安全性和耐受性是很重要的。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。