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Tungsten –Copper alloy is the composite of Tungsten and Copper which own the excellent performances of Tungsten and Copper, such as heat-resistant, ablate-resistant, high-intensity,high-density, excellent thermal and electrical conductivity. It is easy to be machined. It is used widely in such industries as engine, electric power, electron, metallurgy, spaceflight and avigation.

钨铜材料是钨和铜的一种合金，综合了钨和铜的优点，耐高温、耐电弧烧蚀、强度高、比重大、导电、导热性好，易于切削加工，并具有发汗冷却特性，作为真空触头材料、电极材料、电子封装材料以及火箭、导弹特殊用途材料等广泛应用于机械、电力、电子、冶金、航空航天等工业。

Obvious difference was showed in the expression level of CDR1 gene between azole resistant and sensitive isolate.

1。观察到目前肾移植患者人群白念珠菌分离株可能存在唑类耐药，并发现唑类耐药的发生与分离部位没有明显相关。

The overexpression of CDR1, CDR2, and MDR1 is a common theme in azole antifungal resistance in C.

其中多药耐药基因CDR1、CDR2、MDR1的表达增加是唑类耐药主要机制，有研究表明CDR1、CDR2、MDR1的过度表达与转录调控因子有关，但具体机制不清。

In the present study, we examined the large-scale gene expression profiles with six sets of matched clinical and experimental fluconazole susceptible and resistant C. albicans strains by microarray analysis. We observed that azole resistances developed in multiple circumstances are all associated with increased expression of CDR mRNA. We also identified some common differential expressed genes and some interesting function-linked gene groups involved in drug-resistance.

利用所构建的基因芯片我们研究了共六对氟康唑敏感和耐药白念珠菌配对菌株的大规模基因表达谱，证实不同环境下产生的白念珠菌耐药性均与多药耐药基因CDR的mRNA表达增加有关，并从中鉴定了一些与药物耐受性相关的共同差异表达基因和一些有趣的功能连锁基因群。

And according the results of the fluconazole sensitivity, differential expression level of CDR1 mRNA was showed on the candida albicans azole resistance and sensitive isolates, we want to discover the molecular mechanism of CDR1 expression regulation by detecting whether there were the mutations on the upper stream of the CDR1 gene.

CDR1基因在白念珠菌唑类耐药/敏感菌株中的表达情况观察，对念珠菌的mRNA进行NORTHERN BLOT检查，发现唑类耐药株与敏感株在CDR1基因表达上存在显著差异。3。

And according the results of the fluconazole sensitivity, differential expression level of CDRl mRNA was showed on the Candida albicans azole resistance and sensitive isolates, we want to discover the molecular mechanism of CDRl expression regulation by detecting whether there were the mutations on the upper stream of the CDRl gene.

CDRI基因在白念珠菌哇类耐药／敏感菌株中的表达情况观察，对念珠菌的mRNA进行NORTHERN BLOT检查，发现哇类耐药株与敏感株在CDRI基因表达上存在显著差异。3。

The azole drugs including fluconazole target lanosterol 14α-demethylase, the product of the ERG11 gene. Ergllp is one of the enzymes in the biosynthesis of ergosterol, the major sterol of fungal membranes and an analogue of cholesterol in mammalian systems.

唑类药物外流也是导致唑类耐药的主要原因，而与之药物外流泵相关的基因有ATP结合盒转运子基因(ATP Binding Cassette Transporter)——CDR1、CDR2和主要易化子基因——MDR1、FLU1，他们的过度表达可以导致唑类耐药的发生。

Transmission of the main sales agents various types of industrial belt: Germany orbit, Japan Bando Samsung Song, the United States Gates, Italy, and so Mr Gaudi Brand-name industrial belt, double-sided tooth belt, T2.5, T5, T10, T20, AT5, AT10, AT20, DT5, DT10, DT20 Metric timing belt, with variables, production and sales network of stainless steel conveyor belt, high temperature iron fluoride Long network zone, with Juan Zhi network, with high temperatures blankets; PVC, PU, PE, SIR conveyor belt, anti-static tape.

传动件主要代理销售各类工业皮带：德国奥比特，日本阪东三星松田，美国盖茨，意大利麦高迪等名牌工业同步带，双面齿同步带，T2.5，T5，T10，T20，AT5，AT10，AT20，DT5，DT10，DT20公制同步带，变数带，生产销售不锈钢输送网带，耐高温铁氟龙网带，聚胺脂网带，耐高温毛毡带；PVC，PU，PE，SIR输送带，防静电胶带。

RG resistance is uranium metal plating on the top bar magnet, has excellent impact resistance characteristics and high voltage, high reliability, pulse load capability, low voltage coefficient of performance, widely used in communications equipment, high-quality power supplies and other areas .

RG 电阻是用金属铀镀于磁棒上面，有着极佳的耐冲击特性及耐高压，可靠性高、脉冲负载能力强、电压系数低等性能，广泛地使用于通讯设备、高质量电源等领域。

Disney Characters A timeline of character debuts Before Mickey 1924 Alice (of The Alice Comedies, a series of 56 silent cartoons) 1927 Oswald the Lucky Rabbit (star of 26 silent cartoons) Recurring Characters: Mickey and Friends 1928 Mickey Mouse and Minnie Mouse, in Steamboat Willie 1929 Peg-Leg Pete, in The Barn Dance 1929 Clarabelle Cow and Horace Horsecollar, in The Plow Boy 1930 Pluto (AKA "Rover"), in The Chain Gang 1932 Goofy (AKA "Dippy Dawg,""George Geef"), in Mickey's Revue 1934 Donald Fauntleroy Duck, in The Wise Little Hen 1937 Huey, Dewey, and Louie Duck, in the Donald Duck Sunday comics 1937 Daisy Duck (AKA "Donna Duck"), in Don Donald 1943 Chip 'n' Dale, in Private Pluto Stars of Disney Feature Films 1937 Snow White, in Snow White and the Seven Dwarfs 1940 Pinocchio and Jiminy Cricket, in Pinocchio 1941 Dumbo, in Dumbo 1942 Bambi, in Bambi 1950 Cinderella, in Cinderella 1951 Alice and the White Rabbit, in Alice in Wonderland 1953 Peter Pan and Tinkerbell, in Peter Pan 1955 Lady and Tramp, in Lady and the Tramp 1959 Aurora, in Sleeping Beauty 1961 Pongo, Perdita, and the pups, in 101 Dalmatians 1967 Mowgli and Baloo, in The Jungle Book 1974 Robin Hood and Maid Marian, in Robin Hood 1986 Basil, in The Great Mouse Detective 1989 Ariel, in The Little Mermaid 1991 Belle and Beast, in Beauty and the Beast 1992 Jasmine and Aladdin, in Aladdin 1994 Simba, Timon, and Pumbaa, in The Lion King 1995 Buzz Lightyear and Woody, in Toy Story 1995 Pocahontas, in Pocahontas 1996 Esmerelda, in The Hunchback of Notre Dame 1998 Hercules and Megara, in Hercules 1998 Mulan and Mushu, in Mulan 2001 Milo Thatch, in Atlantis: The Lost Empire 2001 Lilo and Stitch, in Lilo And Stitch 2002 Sulley, in Monsters, Inc.

狄斯耐人物一个个性初次登场的时间期限在米奇之前 1924 爱丽丝(爱丽丝喜剧，一系列的 56幅沈默的卡通) 1927 奥斯瓦德幸运的兔子(26幅沈默的卡通的星)回到个性：米奇和朋友 1928 米老鼠和米妮老鼠，在汽船威利 1929 钉-腿的彼得，在谷仓跳舞方面 1929 Clarabelle 母牛和贺瑞斯 Horsecollar，在犁男孩中 1930 冥王星，在链组织中 1932 古菲(AKA"脑筋不正常的 Dawg，""乔治 Geef")，在米奇的讽刺时事的滑稽剧 1934 唐纳德 Fauntleroy 鸭子，在明智的小母鸡中 1937 Huey ，杜威和中尉鸭子，在唐纳德鸭子星期日连环图画中 1937 黛西没入水中(AKA"堂娜鸭子")，在君唐纳德 1943 削'n'山谷，在私人的冥王星狄斯耐特征电影的星 1937 下雪水于白色，在雪白色的和七个矮子 1940 童话中的主角和表示温和的惊讶蟋蟀，在童话中的主角 1941 Dumbo，在 Dumbo 1942 Bambi，在 Bambi 1950 灰姑娘，在灰姑娘 1951 爱丽丝和白色的兔子，在奇境的爱丽丝 1953 彼得平锅和 Tinkerbell，在彼得平锅 1955 淑女和重步声，在淑女和重步声中 1959 奥罗拉，在睡着的美人 1961 在 101只大麦町中的 Pongo ， Perdita，和学生 1967 Mowgli 和 Baloo，在丛林中订购 1974 罗宾头巾和少女圣母玛利亚崇拜者，在罗宾头巾 1986 罗勒，在伟大的老鼠侦探中 1989 瞪羚，在小的美人鱼中 1991 美女和畜牲，在美人和畜牲中 1992 茉莉属植物和安拉丁，在安拉丁 1994 Simba ， Timon 和 Pumbaa，在狮子星国王中 1995 发出嗡嗡声 Lightyear 和多树木的，在供玩耍的故事中 1995 风中奇缘，在风中奇缘 1996 Esmerelda，在 Notre 夫人的驼背中 1998 大力英雄和 Megara，在大力英雄 1998 Mulan 和 Mushu，在 Mulan 2001 Milo 盖屋顶的材料，在阿特兰提斯：失去的帝国 2001 Lilo 和一针，在 Lilo 和一针 2002 Sulley，在怪物，公司 2003 奈莫舰长，在发现奈莫舰长方面 2004 幼鲑，在难以置信人中

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。