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After treated by alkaline peroxide, the extractive in jack pine TMP long fiber decreased evidently, its surfaces produced large numbers of carboxyl. The H2O2 dosage in AP treated process had evident effect on brightness of sheet. The action of alkali in AP process is to make structure of cell wall loose.

碱性过氧化氢处理 TMP长纤维组分能明显降低浆中抽出物含量,纤维表面产生大量的羧基;过氧化氢用量的变化对白度影响较为明显;碱的作用是使细胞壁结构变得松弛,随着用碱量的增加,抽出物含量明显降低,羧基含量大幅度增加,纤维表面O/C比也略有增加,各项强度均增加。2。

The invention discloses an antibody against cattle piron and method for preparation, wherein the antibody is obtained by using polypeptide selected from the following polypeptide family as the antigen immunological animal, said polypeptide family is formed by the following polypeptides,(1) polypeptide of the amino acid residue sequence 1 in the sequence table,(2) polypeptide obtained by removing 1-24 amino acid residues continuously from No.

本发明所提供的制备牛朊病毒抗体的方法,是以选自下述多肽家族之一的多肽为抗原免疫动物得到的抗体;所述多肽家族由以下多肽组成:1具有序列表中序列1的氨基酸残基序列的多肽;2从序列1的自氨基端第1位氨基酸残基开始向羧基端连续去除1至24个氨基酸残基,和/或从序列1的自氨基端第264位氨基酸残基开始向氨基端连续去除1至23个氨基酸残基得到的多肽。

Any of several esters, other than the ethyl ester, of carbamic acid .

脱羧酶酶的一种,可水解羧基酸

Ferrocenecarboxylic-ssdeoxyribonucleic acid probe was made by chemically bounding FCA to terminal 5'-amino of oligonucleotide in the presence of a water-soluble carbodiimide. The hybridization reaction was conducted by immersing the immobilized-ssDNA electrode in FCA-ssDNA probe solution.

在偶联活化剂碳二亚胺的存在下,通过羧基二茂铁上的羧基与DNA分子上的氨基共价键合,将FCA标记在氨基修饰的寡聚核苷酸片段上,制备成FCA-ssDNA探针。

The results showed that a violet phosphine coordinated cobalt salt,(C10H21COO)2Co…(PBu3)n, was first formed as the solution of cobaltous naphthenate.

由于羧酸和钴-膦羧基络合物可以构成可逆循环反应,因而阻止了催化剂的分解。

Several types of ligand reactions observed under hydrothermal condition were summed up:(1) hydrolysis of pyridine nitrile, aldehyde and ester in mixed water and alcohol into pyridine-carboxylate;(2) replacement of carboxylate group with sulfonic group;(3) coupling of phenanthroline by dehydrogen;(4) oxidative coupling of methanol into oxalic acid;(5) hydroxylation of isophthalate.

总结了以往在水热条件下观察到的几类配体反应:(1)吡啶腈、醛和酯在醇和水混合溶液中水解成吡啶羧酸;(2)磺基取代羧基反应;(3)邻菲啰啉的脱氢的聚合:(4)甲醇被氧化偶合生成草酸:(5)间苯二甲酸的羟基化反应。

A compound of formula wherein R1 is hydrogen, halo or methoxy; R2 is hydrogen, halo, methyl, ethyl or methoxy; R3 is carboxy, tetrazolyl, or -CONHSO2R where R is methyl, ethyl, phenyl, 2,5-dimethylisoxazolyl or trifluoromethyl; T is -CH2- or -SO2-; and ring A is 3-chlorophenyl, 4-chlorophenyl, 3-trifluoromethylphenyl, 3,4-dichlorophenyl, 3,4-difluorophenyl, 3-fluoro-4-chlorophenyl, 3-chloro-4-fluorophenyl or 2,3-dichloropyrid-5-yl; or a pharmaceutically acceptable salt or prodrug thereof, as well as pharmaceutical compositions containing them are described and claimed.

本发明涉及一种式化合物,其中R 1 是氢原子、卤素或甲氧基;R 2 是氢原子、卤素、甲基、乙基或甲氧基;R 3 是羧基、四唑基或-CONHSO 2 R 4 ,其中R 4 是甲基、乙基、苯基、2,5-二甲基异∴唑基或三氟甲基;T是-CH 2 -或-SO 2 -;环A是3-氯苯基、4-氯苯基、3-三氟甲基苯基、3,4-二氯苯基、3,4-二氟苯基、3-氟-4-氯苯基、3-氯-4-氟苯基或2,3-二氯吡啶-5-基;或其药用允许的盐或前药,还包括所阐述和要求权利的含有它们的药用组合物。

The results show that the perfect Honeycomb pattern films without defects within area of 0.8cm^2 can be obtained at the PS concentration ranges from 20 mg/mL to 50 mg/mL and PS/TEOS mass ratio less than 2. The films cast from the chloroform solution of dicarboxyl terminated PS were more perfect than those cast from the chloroform solution of monocarboxyl terminated PS. The perfect Honeycomb structure films could be obtained with both chloroform and benzene as solvents, but the pore diameter of films cast from benzene solution of PS was larger than that of films cast from chloroform solution of PS.

研究结果表明,聚合物浓度在20~50mg/mL,PS/TEOS质量比大于2:1的条件下可以制备结构完整的多孔膜,且制备的Honeycomb结构在0.8平方公分内无缺陷;采用双羧基封端的聚苯乙烯成膜效果好于单羧基封端的成膜效果;以氯仿和苯作为溶剂均可以制备完全Honeycomb结构的复合膜,但以苯为溶剂制备的多孔膜孔径较大。

BACKGROUND: The carboxyl terminuses of the Hsc70-interacting protein associate with many proteins in neurodegenerative diseases, which can promote the degradation of these proteins. Therefore, it is of a great significance to study the function of CHIP.

背景:热休克蛋白70羧基末端相互作用蛋白与许多神经退行性疾病的相关蛋白质存在相互作用,并促进这些蛋白质的降解,因此对热休克蛋白70羧基末端相互作用蛋白功能的研究具有非常重要的意义。

The latter is chlorinated in the side chains under free-radical conditions to give 2,4-dichloro-5-fluoro-3-dichloromethyl-1-trichloromethylbenzene. The latter is hydrolysed via 2,4-dichloro-5-fluoro-3-dichloromethylbenzoic acid, which can be isolated if necessary, to give 2,4-dichloro-5-fluoro-3-formyl-benzoic acid, the aldehyde group of which is reacted to give 2,4-dichloro-5-fluoro-3-N-hydroxyiminomethyl-benzoic acid, from which, with simultaneous conversion of the carboxyl group into the chlorocarbonyl group, water is eliminated using an acid chloride to give the nitrile 2,4-dichloro-3-cyano-5-fluoro-benzoyl chloride.

随后,在游离基条件下进行侧链的氯化,得到2,4-二氯-5-氟-3-二氯甲基-1-三氯甲基苯、后者被水解,经过2,4-二氯-5-氟-3-二氯甲基苯甲酸(如果需要此化合物可以分离),得到2,4-二氯-5-氟-3-甲酰苯甲酸,将其醛基反应,得到2,4-二氯-5-氟-3-N-羟基亚氨基甲基苯甲酸,用酰氯从其中除去水,同时将羧基转化为碳酰氯,得到一种腈,即2,4-二氯-3-氰基-5-氯-苯甲酰氯。

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