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ABSTRACT: In the presence of sodium t-butoxide and DMSO,ethyl 2-oxocyclopentanecarboxylate was subjected to C-alkylation with 2-(4-bromomethylphenyl)propanoic acid with high regioselectivity to give 2-[4-(1-ethoxycarbonyl-2-oxo-1-cyclopentanylmethyl)phenyl]propanoic acid (4) which was followed by hydrolysis,decarboxylation and salt formation to afford loxoprofen sodium in about 72% overall yield.

在叔丁醇钠和二甲基亚砜的存在下,2-丙酸对2-乙氧羰基环戊酮进行C-烷基化,再经水解脱羧,成盐即得洛索洛芬钠,以2-丙酸计算,总收率为72%。

Through repetitious filtration to synthetic methods, it was proved that Stobe reaction can be used in the synthesis of γ-oxoacyl heliotropin.

反复筛选合成方法结果证明将Stobbe反应及其在合成γ-羰基羧酸的应用用于本研究工作中,初见成果。

Among analyzed 197 synthetic genes on chip, approximately 60 genes have been expressed, including 18 two-component/kinase, 10 glycolysis/TCA, 3 gene clusters, 7 regulators, 5 asaption/celldivision/differentiation/sporulation, 4 transport/binding proteins, 2 chaperones, 5 RNA polymerase sigma-factors, 3 transcription/translations, 2 fatty acid synthesises and 1 RNA polymerase β subunit.

对芯片上的197个合成基因进行分析:大约有60个基因进行了表达,其中包括18个双组分或激酶基因;10个糖酵解或者三羧酸循环途径基因;3个阿维基因簇;7个调节基因;5个细胞分化或孢子形;4个运输或固定基因;两个伴侣分子;5个RNA聚合酶σ因子;3个转录基因;两个脂肪酸合成基因;1个RNA聚合酶β亚基。

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你知道吗,我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书,王祥生,李德昌。安徽省首次发现嗜群血蜱。

Chapter Three: Type classification of DE structure in Sino-Tibetan languages.

第三章汉藏语&的&字结构的类型划分。