羧基

After esterification, the ethyl-2-chloro-3-phenylpropionate reacts with diethyl malonate under the catalysis of sodium ethylate, and we obtain the corresponding triethyl ester. The-benzylsuccinic acid is formed by the triethyl ester reacting with concentrate hydrochloric acid and taking place hydrolyzation and decarboxylation reaction at the same time. In order to avoid the formation of cinnamic acid, the sodium ethylate and diethyl malonate must be react sufficiently. The course has simple operation, inexpensive materials and better yield.

具体制备工艺为：首先以L-苯丙氨酸为原料采用重氮化方法得到-2-氯-3-苯基丙酸，再经酯化得到-2-氯-3-苯基丙酸乙酯后在乙醇钠催化作用下和丙二酸二乙酯缩合，发生SN2反应，得到相应的三乙酯，然后经水解和脱羧，得到-苄基丁二酸；在实验中乙醇钠要和丙二酸二乙酯充分反应，避免生成肉桂酸乙酯；该过程操作简单，原料便宜，产率较高，总收率可达到26.8%。

The effects of sodium starch glycolate as binder onthe disintegration and dissolution of the tablets of SD and Aspirin were inves-tigated compared with those binders such as HPMC,gelatin and starch.

实验考查了羧甲基淀粉钠作为粘合剂对磺胺嘧啶、阿司匹林片剂的崩解和溶出度的影响，并与羟丙基甲基纤维素、明胶和淀粉浆做了比较。

From the reaction mechanism, which involved formation of benzodiazepinium ethoxycarbonylmethylate, the reaction mechanism, which involved formation of benzodiazepinium ethoxycarbonyl- methylate followed by cycloaddition reaction, was tentatively proposed.

通过研究反应过程中分离出的副产物反丁烯酸二乙酯III和4，5-二氢吡唑-3，4，5-三羧酸乙酯IV，初步提出了反应经过乙氧羰基甲基化苯并二氮杂卓翁中间体V再发生环加成反应的机制。

objective to sodium carboxy methyl cellulose and glycerol as gel matrix ingredient and kelp and motherwort extract condensate made uniform gels, the greatest degree of reserves of natural beauty material components to play the efficacy of beauty.

目的 以羧甲基纤维素钠和甘油作为凝胶基质主要成分与海带浸膏及益母草提取液制成均一凝胶剂，最大程度的保留美容物质的天然成分使之发挥美容的功效。

The nitrosation of cyclohexanecarboxylic acid with nitrosyl sulfuric acid is an important industrial process to produce ε-caprolactam.

由环己烷羧酸与亚硝基硫酸的亚硝化反应制取己内酰胺是一个重要的工业反应过程。

The solubilities in some solvents were investigated and solubilization abilities of OCC for water-insoluble drugs were evaluated. The results show that the degree of substitution of carboxymethyl groups and octyl groups are determined to be 115.9% and 58.0%, respectively. OCC are insoluble in organic solvents while show a much better solubility in water and formed opalescence solutions, which increased the solubility of paclitaxel up to 500 folds in water. The drug loading and drug encapsulation efficiency of OCC are 34.6% and 89.9%, respectively.

所制备的OCC羧甲基取代度为115.9%，取代主要发生在6位羟基上；辛基取代度58.0%，取代主要发生在2位氨基上；与壳聚糖相比，OCC分子间／内氢键作用减弱；OCC在常用的有机溶剂中不溶，但在水中溶解度增加，能够形成具有淡蓝色乳光的纳米胶体溶液，对难溶性抗肿瘤药物紫杉醇具有优越的增溶能力，使紫杉醇在水中的溶解度提高近500倍，载药量34.6%，包封率为89.9%。

The optimum synthesizing conditions of phosphonoarboxylic acid cotelomer are determined by a series of orthogonal experiments.

通过正交实验确定了膦酰基羧酸共调聚物的最佳合成工艺条件。

We examined the effects and mechanisms of methyl pentyl 1,4-dihydro-2,6-dimethyl-4-(3-notrophenyl)-3,5-pyridinedicarboxylate (Mn9202), a novel DHPs calcium antagonist and lacidipine on the 5-HT2B receptor in cultured rat stomach fundus smooth muscle cells.

本研究以富含5-HT_(2B)受体的大鼠胃底平滑肌细胞为模板，观察了二氢吡啶类钙拮抗剂2，6-二甲基-4-（3-硝基苯基）-1，4-二氢-3，5-吡啶二羧酸-3-甲酯-5-正戊酯（Mn9202）、拉西地平对 5-HT_(2B)受体功能的影响，并对其影响机制进行了较为深入的研究。

Results A new quinoloe alkaloid named 8-methoxy-4-quinolone-2-caboxylic acid was isolated from L. echinata and was found to have antibacterial activity on Pseudomonas pyocyanea ATCC 27853, EPEC O111, pneumobacillus and Staphylococcus epidermidis.

结果 从东北鹤虱中分离出一个新喹酮类生物碱，鉴定为8-甲氧基－4-喹酮－2-羧酸，并对铜绿假单胞菌、肠致病性大肠埃希菌、肺炎克雷伯菌及表皮葡萄球菌具有抗菌活性。

The influences of different organic bridging ligands pyrazine,2-pyrazinecarboxylate,4,4′-bipyridine and 1,2-bis(4-pyridyl)ethane on the cobalt vanadate system were explored.

同时还研究了不同的有机桥式配体吡嗪、2-吡嗪羧酸、4，4′-联吡啶和1，2-联(4-吡啶基)乙烷在钴钒体系中的作用。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。