羧基

Novel chitosan derivative with long alky groups as the hydrophobic moieties and carboxymethyl groups as the hydrophilic moieties was synthesized. The chemical structure of N-octyl-O, N-carboxymethyl chitosan was characterized via FTIR, 1H NMR and elemental analysis. The physical properties were analyzed with wide angle X-ray diffraction and differential scanning calorimetry.

以天然可生物降解的壳聚糖为原料，通过在壳聚糖6位羟基上引入羧甲基，在2位氨基上引入疏水烷基链，制得N-辛基－O，N-羧甲基壳聚糖两亲性衍生物，分别用FTIR、1H NMR和元素分析等技术对其结构进行表征，用广角X射线衍射和差示扫描量热法对具物理性质进行分析，并考察其在各种溶剂中的溶解性能及其对难溶性药物的增溶能力。

In the present study, Hartree-Fock and Density Functional Theory with different basis sets were employed to calculate the structural and thermodynamic parameters of 66 thiophenyl, phenyl sulfoxide and phenylsulfonyl cycloalkane carboxylates. With the statistic software SPSS11.5 for windows and GQSARF2.0, the QSAR models relating physicochemical properties of these compounds to their structural and thermodynamic parameters were successfully obtained, using multiple stepwise regression method. The physicochemical properties observed in this work include octanol/water partition coefficient, chromatographic capacity index, toxicity (EC50 and LC50), and solubility etc.

本文采用从头算方法中的Hartree-Fock 方法、密度泛函理论方法(Density functional theory，简称DFT)中的不同基组，计算了苯硫基、苯亚砜基和苯砜基含硫芳香羧酸酯三类共66 个化合物的结构参数和热力学参数，利用SPSS11.5 for windows 统计软件和GQSARF2.0 软件，采用多元逐步回归法拟合得到与溶质-溶剂相互作用有关的物理化学性质与结构参数和热力学参数之间的QSAR 方程，这些物理化学性质包括辛醇/水分配系数、色谱容量因子、毒性(EC50和LC50)、溶解度等。

Agent TJ-201 is an organic phosphonocarboxylic acid containing maleic group, p hosphonic group, and ethoxyl group etc.

TJ-201是一种含马来酸基、磷酸亚基、氧乙烯基等的膦基聚羧酸。

ABSTRACT Agent TJ-201 is an organic phosphonocarboxylic acid containing maleic group, p hosphonic group, and ethoxyl group etc.

摘 要 TJ-201是一种含马来酸基、磷酸亚基、氧乙烯基等的膦基聚羧酸。

They have close relationship as the former may provide new ideas and approaches for the later, while the later may be the simulation for the former and gives it helps in degradation products identification and mechanism explanation. It is necessary to choose a suitable system, which has high potential of treating EDs and close relationship to the natural environment, to combine the researches in the two aspects. Our group has been engaged in researches on the photochemical properties and application to water pollution control of different ferric species including Fe -OH complexes, Fe -polycarboxylate complexes, Ferric oxides and Fe -humic acid complexes. Fe -oxalate complexes system has higher efficiency than the other ferric species systems in photooxidation and degradation of organic compounds. This thesis is focused on the photodegradation of nine EDs estradiol (E2), estrone (E1), 17α-ethynyl estradiol (EE2), diethylstilbestrol , bisphenol-A , 4-Nonylphenol , 4-Octylphenol , di-n-butyl phthalate , and di (2-ethylhexyl) phthalate .

因此从处理效率和环境化学意义两方面考虑，结合本课题组在不同铁形态（包括Fe-OH配合物、Fe-多羧酸配合物、Fe氧化物、Fe-腐殖酸配合物等）的光化学特性及其在水污染控制中的应用方面较系统的研究工作基础，本论文选择了四类共9种典型的内分泌干扰物（雌二醇（E2）、雌酮（E1）、17α-乙炔基雌二醇（EE2）己雌酚、双酚A、壬基酚、辛基酚、酞酸二丁酯和酞酸二乙基己基酯），研究了它们在Fe-草酸盐配合物体系中的光降解效果，推测其降解机理，探索环境内分泌干扰物光氧化处理的新体系，同时为预测其在环境中的光降解行为提供了依据。

A series of cholesterol-bearing O-carboxylmethyl chitosan conjugates with different degrees of substitution of the cholesterol moieties and cholesterol-bearing chitosan were synthesized by the succinyl linkages and characterized by Fourier transform infrared, Proton Nuclear Magnetic Resonance (~1H NMR) and elemental analysis. These hydrophobized chitosan derivatives were amphiphilic in nature and their self-aggregation behavior in aqueous media was evaluated by the fluorescence probe technique.

课题的主要研究内容如下：采用化学的方法合成了不同分子结构、不同取代度的系列胆甾醇基壳聚糖衍生物—胆甾醇基壳聚糖和胆甾醇基-羧甲基壳聚糖，并应用先进的分析手段电位滴定、红外光谱法(IR、核磁共振波谱法等对原料、中间产物以及产物进行了结构表征，衍生物分子中的胆甾醇基取代度(3.2％～12.5％)采用元素分析的方法进行检测。

A process for the carbonylation of allylic butenyl ether (for example, methyl crotyl ether, 3-methoxybutene-1 and mixtures thereof) or mixture of butadiene and alcohol and production of beta-gamma unsaturated carboxylic acid esters (for example, methyl-3-pentenoate) utilizing a rhodium-containing catalyst for example, dicarbonylacetylacetonate rhodium(I or the like promoted with an iodide-containing compound (for example, HI, AlI3, SnI4, TiI4, CrI3, and CoI2 or the like).

一种将烯丙型丁烯基醚(如甲基巴豆基醚、3－甲氧基丁烯－1及其混合物)或者丁二烯与醇的混合物羰基化的方法，以及由含碘化物化合物(如HI、AlI3、SnI4、TiI4、CrI3和CoI2或等效物)促进，用含铑催化剂如二羰基乙酰丙酮酸铑(I或其等效物制备β－γ不饱和羧酸酯(如甲基－3－戊烯酸酯)的方法。

In the presence of catalytic rhodium acetate, ethyl 2-diazo-3-oxo-per fluoroalkanoates, reacted readily with nitriles to give a series of 5-fluoroalkyl substituted 1, 3oxazoles with high regio-selectivity through a metal carbenoid intermediate. The reactions of carbenoids with noncyclic vinyl ethers or cyclic vinyl ethers afforded dihydrofuroates in good to excellent yields. Interestingly, only vinyl C-H insertion compound was obtained concerning of the reaction of carbenoids with 2, 5dimethylfuran due to the steric hindrance of methyl group

醋酸铑分解2-重氮-3-氧代-全氟羧酸乙酯形成的金属卡宾作为1，3-偶极体，可以与一系列芳基或烷基取代的腈反应，高度区域选择性地生成一系列4-乙氧羰基-5-氟烷基取代的噁唑化合物；也可以与富电子的链状和环状的烯基醚反应，以优良的产率得到一系列氟烷基取代的二氢呋喃类化合物；而与2，5-二甲基呋喃的反应，由于甲基的位阻作用，只得到金属卡宾对呋喃3-位烯基碳氢键插入产物。

And the ability of antioxidant of polyhydroxy benzamides don't have too many differences with Trolox (IC50 =13.90 μg/ml), the substition of hydroxy group at amino benzene ring doesn't affect the whole ability of antioxidant apparently, but while the single hydroxy group at carboxylic acid benzene ring, they are apparently decrease to scavenge the ability of free radical, as a result, the hydroxy at amino benzene ring substitutes its function, without the hydroxy group, the ability of antioxidant is worst, but it upgrades its function while the hydroxy and amino are in the ortho-position or para-position.

而当多酚醯胺化合物其抗氧化能力与Trolox差不多时(IC50 =13.90 μg/ml)，胺基苯环上之羟基取代对整体抗氧化能力影响不明显，但在羧酸苯环上具单羟基时，其清除自由基能力明显下降，使得胺基苯环上羟基取代发挥了影响力，无羟基取代时，抗氧化能力最差，而羟基与胺基互为邻位或是对位时较间位有提升效果。

A convenient method to synthesize three kinds of novel 2-(2-hydroxyphenyl) benzimidazole in order to improve the solubilities of the fluorophores with substituent of carboxyl, ester and double-bond which are aimed for determining the sulphydryl group was reported.

合成了N-{3-(2-苯并咪唑基)-4-羟基苯基}马来酰亚胺酸， N-{3-(2-苯并咪唑基)-4-乙酸酯基苯基}和马来酰亚胺N-{3-(2-苯并咪唑基)-4-羟基苯基}马来酰亚胺，在基本荧光发射团上分别引入了羧酸基；酯基；双键活性基团。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。