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羟脯氨酸

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Hepatic pathology diagnosed them as mild and moderate steatohepatitis, and focal perisinous fibrosis developed in liver acinus's area 3 zone.

但不饱和脂肪酸组血浆ET、TNF-α明显高于饱和脂肪酸组,血浆HA、LN、TGF-β1及肝脏羟脯氨酸含量均显著高于饱和脂肪酸组。

On days 14, serum proteins and amino acids concentration and peripheral lymphocyte blastogenesis were determined. At the end of the study, the animals were sacrificed, hydroxyproline and tensile strength of wound, and intestinal mucosal DNA, RNA and protein content were examined.

测定饲料摄入量、体重、氮平衡、血浆蛋白和氨基酸含量、外周血淋巴细胞转化率、伤口埋植海绵中羟脯氨酸含量、皮肤抗张力强度和小肠粘膜蛋白质及核酸。

The results showed: the calcium, phosphate and ALP in blood in the osteoporosis rats induced by DXM were normal, the bone ash wight, bone dense and intestinal Ca2+ absorption were declined compared with these of the normal rats (p.05). Afterwards, the osteoporosis rats were treated with replenishing kideny herbs or calcium.

实验结果发现,地塞米松诱发的骨质疏松大鼠的血钙、磷、碱性磷酸酶及尿羟脯氨酸均在正常水平,骨密度、骨灰重下降,肠钙吸收减少,与正常大鼠比较有统计学差异(P.05),血中雌二醇、1,25-2-D3水平降低(P.01,P.05),PGE2升高(P.05),经过补肾中药或钙剂治疗后,血雌二醇、1,25-2-D3水平回升而PGE2回降,均接近正常水平。

Compared with model group, cp groups alleviate cell crimple could increase the activity of cell, decrease the content of MDA, and increase the level of HYP and the activity of SOD.

结果光老化组细胞发生形态改变,增殖能力明显下降,羟脯氨酸含量下降,丙二醛含量升高,SOD活力下降,虫草保护组细胞有所改善。

MethodsPhotoaging skin fibroblast models were induced by 8-MOP/UVA. Cordyceps polysaccharides was administrated before 8-MOP/UVA .HE stained,MTT, hydroxyproline, MDA and SOD quantitant were used to test the effects of cordyceps polysaccharides. ResultsCell crimple,condensation of nuclear chromatin in 8-MOP/UVA model group were observed.

方法用8-甲氧补骨脂素联合UVA(8-MOP/UVA)诱导皮肤成纤维细胞光老化,用HE染色、MTT、羟脯氨酸含量、丙二醛含量检测及SOD活力分析等方法观察虫草多糖对成纤维细胞光老化过程中的形态、活力、胶原合成及抗氧化能力的影响。

To better understand the principles of enzymatic unhairing, changes of contents of protein, hydro-proline and glucose in depilatory liquors were determined in Lowery method, DMBA method and Sulfuric Acid-Anthrone method, respectively, during bath dehairing procedure of 2709 proteinase and A.

为更好地理解酶脱毛的机理,本文用Lowery法、对二甲胺基苯甲醛法和硫酸-蒽酮法分别测定了2709酶和A.S1398酶有温有浴酶脱毛过程溶液中的总蛋白、羟脯氨酸及糖含量的变化。

aim to study the efficaciousness of wuling cap-sules for hepatic fibrosis in rats.methods rat models with hepatic fibrosis were induced by ccl4 compound factors and then treated with wuling capsules.pathology of liver sections,hyaluronic acid and procollagencontents in rat liver and serum were examined respectively.results pathological examinations showed that the liver cells of mod-el rats were injured seriously.collagen fibers proliferated and dissected hepatic lobules in model rats.wuling capsules could protect liver cells and reduce degrees of hepatic fibro-sis.the best effects were achieved at3.0g?

目的 研究五灵胶囊对大鼠肝纤维化的作用。方法采用以四氯化碳为主的复合因素致大鼠肝纤维化,观察五灵胶囊对肝组织病理学、肝组织和血清中羟脯氨酸、ⅰ,ⅲ型前胶原含量的影响。结果病理学检查显示,模型组大鼠肝细胞损伤严重,胶原纤维大量增生,形成假小叶。五灵胶囊组大鼠肝细胞结构破坏不明显,肝纤维化程度轻,在3.0g?kg-1 时治疗效果最好。

RESULTS The proliferation of fibroblasts was inhibited by K102 in vitro. A dose-dependent antagonistic effect was found between K102 and bFGF. The serum levels of ALT, AST and the liver hydroxyproline level in the treated groups were lower than that in the CCl4 model group. Pathological examination showed a slight fatty degeneration and hydropic degeneration was observed in the group treated with the high dose K102, the low dose K102, and the control group.

结果体外生物活性检测:K102明显抑制成纤维细胞的生长,bFGF对K102有一定拮抗作用,且具有剂量依赖性;体内生物活性检测:治疗给药组血清ALT,AST和肝组织羟脯氨酸含量较CCl4模型组明显改善。

At 4,8,12 weeks after operation,the articular cartilages of tibial plateau were taken and the contents of uronic acidand hydroxyprolineand the water ratioin the cartilage were determined.

术后 4、 8、 1 2周取胫骨平台软骨做糖醛酸、羟脯氨酸含量及含水率的测定。

In the measurement of the hydroxyproline in the collagen,the traditional acid hydrolysis method is that under 110 ℃ the animal organism is hydrolyzed with 6 mol/L HCl,for 24 h.

在胶原的羟脯氨酸测定中,传统的酸法水解是在110℃下使用6 mol/L的HCl消解24 h,其操作步骤繁琐且所花时间较长。

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