羟脯氨酸

The nitrogen balance on days 8 was remarkably improved in experimental and normal diet groups compared with control group. There were highter serum glutamine and BCAA concentration, hydroxyproline content and tensile strength of wound, and better lymphocyte blastogenesis in experimental group compared with control and normal diet groups. Experimental and normal diet groups had higher mucosal DNA, RNA and protein content than control group.

实验组动物的血浆谷氨酰胺、BCAA含量，外周血淋巴细胞转化率，伤口皮肤抗张力强度和羟脯氨酸含量都显著高于对照组和正常饲料组(P＜0.05)；实验组和正常饲料组动物第8天氮平衡，小肠粘膜核酸和蛋白质明显高于对照组(P＜0.05)。

Experimental research indicates:QZZGX granule can treat alcoholic fatty liver and DL桬thionine aminoacid fatty liver of the mouse by adjusting metabolism of fat, descending the level of TG,Gn in the liver, improving liver function, anti梠xidat ion descending the content of oxyproling hydroxyproling and improving the level of NO in the body.

实验研究表明：该药对酒精性和乙硫氨酸脂肪肝大鼠通过调节脂肪代谢、降低肝内TG、Gn水平、对酒精性脂肪肝大鼠改善肝功能、抗氧化、降低羟脯氨酸含量和改善体内一氧化氮水平等途径达到治疗脂肪肝的目的。

A method of capillary electrophoresis with tris (2,2′-bipyridyl) ruthenium electrochemiluminescence detection has been applied to the simultaneous determination of proline and hydroxyproline in human urine.

1引言胶原蛋白中常含有丰富的脯氨酸和羟脯氨酸，其中Hyp几乎为胶原蛋白所特有。在胶原蛋白代谢中，Pro通过羟基化形成Hyp，胶原蛋白降解释放的Hyp从尿中排泄[1]。

Objective To investigate the alterations in activity of N-acetyl-β-glucosaminidase in experimental hepatic fibrotic rats.

目的 研究肝纤维化大鼠模型N-乙酰-β氨基葡萄糖苷酶活性的变化及与羟脯氨酸和透明质酸的相关性。

It contains the amino acids needed by the body, such as alanine, arginine, glutamic acid, amion acetic acid, oxyproline, etc. which are very important to the parenchyma, skin, etc. of the body. More importantly, its molecular structure is from very minute to 1000 daltons, so it can be absorbed by the body easily to bring the due effect in the body.

富含涵盖体内所需的氨基酸如：丙胺酸、精氨酸、谷氨酸、氨基乙酸、羟脯氨酸等，对人体软组织、皮肤等非常重要的氨基酸，更重要的是拥有极度微小至1000道尔顿的分子结构，易于被人体吸收并在体内发挥达到应有的效果。

Drugs inhibiting collagen hydroxylation and accumulation are expected to improe this situation, making prolyl 4-hydroxylase (P4H), the key enzyme of intracellular collagen processing, a rational target for pharmacological interention.

抑制胶原羟化和沉积的药物被临床医生所期盼，生成的羟脯氨酸酶{P4H}，肝内细胞胶原生成的关键酶，是药物介入的理想目标。

Hydroxy praline – The main sources of hydroxyl praline are carrots, lettuce, beetroots, turnips, cucumber, plums, cherries, figs, radishes, grapes, olives, pineapples, almonds and coconut.

羟基脯氨酸-的主要来源羟脯氨酸是胡萝卜，生菜， beetroots ，萝卜，黄瓜，李子，樱桃，无花果，萝卜，葡萄，橄榄，菠萝，杏仁和椰子。

Firstly, synthetic racemates of β- amino acids were resolved into their enantiomers by ehiral ligand - exchange flash chromatography with L - hydroxyproline chemically bonded to irregular silica as the stationary phase and aqueous solution containing cupric ions as the mo

首先合成L-羟脯氨酸硅胶键合手性固定相，用于快速色谱中3-羟基-4-甲氧基-β-苯丙氨酸对映体的制备分离，考察了流动相中Cu^2＋浓度、样品体积等因素对分离的影响。

Yi TAI Compounded Medication "we used bases on the basic theory of TCM,set up "The treatment of invigoratmg spleen and promoting blood by regulating qi",target defiency in origin and excess in superficiality TCM syndrome nature,and take experiments;our research injecting L-Arg into abdomen to induce Spleeh-asthenis rat model,it is a new model which combine diseases and syndromes;immunohistochemic 、 optical mirror and biochemistry value number index number are used to detect the expression of related constrain factor TGF-β_1 mRNA、α-SMA when textnre fabrosis occurs in pancreatic,as nell as significance and relation of hydroxyproline in the process of pancreatic fibrosis,meanwhile observe the disturbace which "Yi TAI Compounded Medication makes,revel the anti-fibrosis mechanism from organization form and molecular level.

本研究采用L—精氨酸分次腹腔注射诱导脾虚型慢性胰腺炎大鼠模型，是一种病证结合的新模型；用免疫组化、光镜等技术和生化指标检测CP时胰实质纤维化的相关调控因素TGF-β_1、α-SMA的表达和血清中羟脯氨酸在胰腺纤维化过程中的作用及相互关系，同时观察了&胰泰复方&对其干预机理，从组织形态学和分子水平揭示了该方抗纤维化的作用机制。

To observe the effects of HASF on viability and collagen synthesis of two cell lines, AgNORs staining, 3H-proline incorporation and HYP determination were carried out.

层析法从兔羊水及胎兔血清中提取HASF并做活性鉴定；用嗜银蛋白染色法、3H-脯氨酸掺入法和羟脯氨酸测定法观察不同浓度的HASF对细胞增殖活性和胶原蛋白合成的影响。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。