羟基酸

Water,c12-20 acid peg-8 ester,octyldodecanol,propylene glycol,coco-caprylate/caprate,cetearyl isononanoate,prunus amygdalus dulcisoil,biosaccharide gum-1,phenoxyethanol,ethylhexyl methoxycinnamate,potassium cetyl phosphate,simmondsia chinensisseed oil,carbomer,glyceryl polymethacrylate,malva sylvestrisextract,glyceryl stearate,cetearyl alcohol,cetyl palmitate,cocoglycerides,c12-13 alkyl lactate,methylparaben,sorbic acid,disodium edta,sodium hydroxide,tocopheryl acetate,benzophenone-3,iris germanica root extract,retinyl palmitate,butylparaben,peg-8,propylparaben,ethylparaben,sodium hyaluronate,chlorhexidine digluconate,tocopherol,ascorbyl palmitate,citric acid,ascorbic acid

水， c12-20 acid peg-8 ester，辛基十二烷醇，丙二醇，coco-caprylate/caprate，鲸蜡硬脂醇异壬酸酯，甜杏仁油，多醣物质，苯氧乙醇，4-甲氧基肉桂酸-2-乙基己基酯，十六烷基磷酸钾，西蒙得木籽油，卡波姆，甘油聚甲基丙烯酸酯，锦葵萃取，甘油硬脂酸，棕榈醇，十六烷基棕榈酸酯，椰油脂酸甘油酯类，c12-13烷醇乳酸酯，对羟基苯甲酸甲酯，山梨酸，乙二胺四乙酸二钠，氢氧化钠，维生素E醋酸酯，二苯甲酮-3，鸢尾花萃取，维他命A酯，对羟基苯甲酸丁酯，聚乙二醇-8，羟苯丙酯，羟苯乙酯，透明质酸钠，洗必泰葡萄糖酸盐，维生素E ，维生素C棕榈酸酯，柠檬酸，抗坏血酸

Their structures were characterized as dihydroconiferyl dihydro-p-coumarate, vanillin, apocynin, p-hydroxybenzaldehyde, syringaldehyde, syringic acid, syringylethanone,α-hydroxypropiosyringone, coniferyl aldehyde, dihydroconiferyl alcohol, 2-hydroxyphenylpropanol, and 3-hydroxy-4-methoxy-phenylethanol, respectively.

结果 从该植物中分离得到12个酚性化合物，其结构分别为二氢松柏醇二氢对羟基桂皮酸酯，香草醛，罗布麻宁，对羟基苯甲醛，丁香醛，丁香酸，丁香乙酮，α-羟基丁香丙酮，松柏醛，二氢松柏醇，2-羟基苯丙醇和3-羟基－4-甲氧基苯乙醇。

Methods 4-Hydroxybenzonitrile (2) as the starting material was transformed to 4-hydroxy-thiobenzamide (3) via thioformylation. And ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (4), which was synthesized via cyclization from 3, was treated with hexamethylenetetramine to generate the intermediate ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (5). The target compound febuxostat (1) was obtained from 5 by etherification, cyanidation, hydrolysis.

以羟基苯腈为原料，经硫代甲酰化得到对羟基硫代苯甲酰胺(3)，3经环合得到2-（4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(4)，4与乌洛托品反应，得到中间体2-（3-甲酰基－4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(5)，之后再经醚化、氰化、水解得到目标产物(1)。

The recent development in the toughening and plasticization of poly or poly(hydroxybutyrate-co-hydroxybutyvalerate) was reviewed.

总结了近年来国内外关于聚羟基丁酸酯和聚羟基丁酸酯-co-羟基戊酸酯共聚物在增韧和增塑改性方面的研究进展。

Better results could be obtained, For 40 hours fermentation, cell dry weight and PHB concentration reached 32.7 g · L-1 and 21.4g · L-1 respectively.The synthesis of Poly (β-Hydroxybutyrate-co-β-Hydroxyvalerate) by the strain G-IIIy from different precusor was studied. It was found that the strain G-IIIy could accumulate PHBV with sucrose as carbon source and propionic acid or valeric acid as precursor . In 2L self-controlled fermentor, the dry cell weight, PHBV concentration and PHBV content reached 35.8g·L-1, 22.6g·L-1 and 38.4% respectively in the case of fermentation for 42 hours and the propionic acid as precursor.

研究了添加不同前体物，G-Ⅲy菌株生产聚β-羟基丁酸和聚β-羟基戊酸共聚物的发酵条件，结果表明，此菌株能以丙酸或戊酸为前体，在蔗糖为碳源的条件下合成PHBV共聚物；在2L发酵罐中，以丙酸为前体，发酵16小时开始流加丙酸，根据发酵液pH值变化控制丙酸流加量，发酵42小时，细胞干重、PHBV产量和含量分别达到35.8g/L，22.6g/L，63.13％。

Alcaligenes eutrophus WSH3 was selected as the strain for the production of polyβ-hydroxybutyrate and copolymer of 3-hydroxybutyrate and 3hydroxyvalerate . This study is aimed at finding an operative way leading to high PHB and PHBV productivity, high yield coefficient and high content of PHB and PHBV. The main research results are as follows

本文以真养产碱杆菌(A.eutrophus)WSH3为聚-β-羟基丁酸和3-羟基丁酸与3-羟基戊酸的共聚物的生产菌株，以实现PHB和PHBV发酵过程的高的生产强度、高的产物对基质的产率系数和高的聚合物含量为目标，进行了PHB及PHBV发酵条件的研究，主要研究内容和结果如下

To further study the chemical constitutes of lipophilic active parts, we prepared Alc95% and Alc50% according to original literature. 20 compounds were isolated by using macroporous resin, silica gel, polyamide, Sephadex LH-20, Rp-18, preparative TLC and preparative HPLC chromato-graphy. The structures of them were elucidated by means of physical and chemical properties, modern spectroscopic analysis techniques—UV、IR、 EI/MS、ESI/MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC. They are nine anthraquinones: chrysophanol (95-1), physcion (95-2), emodin (95-5), aloemodin (95-7), rhein (50-1), sennoside A or B (50-6),ω-hydroxylemodin (95-10), chrysophanol-8-0-β-D-glucoside (95-12), aloemodin-ω-0-β-D-glucoside (95-13); three phenanthaquinones: tanshinone ⅡA (95-3), cryptotanshinone (95-6), tanshinone Ⅰ(95-4); one isoflavone: 7, 3'-dihydroxyl-5' methoxyisoflavone (95-14) and protocaechuic aldehyde (95-9), protocaechuic acid (95-11), astragaloside Ⅳ(50-4), amygdalin (50-5), 2, 3, 5, 4'-tetrahydroxylstilbene-2-0-β-D-glucoside (50-3),-catechin (50-2), cinnamic acid (95-8). Among them, 3'-dihydroxyl-5' methoxyisoflavone (95-14) is a new compound.

经过溶剂萃取、大孔吸附树脂富集、Sephadex LH-20精制、制备TLC及Semi-pre HPLC等手段从中分离了20个化合物，利用理化性质和波谱技术(UV、IR、EI／MS、ESI／MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC)相结合鉴定了它们的结构，分别为9种蒽醌类化合物：大黄酚，大黄素甲醚，大黄素，芦荟大黄素，大黄酸，番泻苷A或B，ω-羟基大黄素(ω-hydroxylemodin)，大黄酚-8-0-β-D-葡萄糖苷(chrysophanol-8-0-β-D-glucoside)，芦荟大黄素-ω-0-β-D-葡萄糖苷(aloemodin-ω-0-β-D-glucoside)；3种菲醌类化合物：丹参酮ⅡA(tanshinoneⅡA)，隐丹参酮，丹参酮Ⅰ(tanshinone Ⅰ)；1种异黄酮：7，3'-二羟基-5'-甲氧基异黄酮（7，3'-dihydroxy-5' methoxyisofla-vone）以及原儿茶醛，原儿茶酸，黄芪甲苷(astragaloside Ⅳ)，苦杏仁苷，2，3，5，4'-四羟基二苯乙烯-2-0-β-D-葡萄糖苷（2，3，5，4'-tetrahydroxylstilbene-2-O-β-D-g1ucoside），Z—儿茶素，桂皮酸。

Water,c12-20 acid peg-8 ester,octyldodecanol,cetearyl isononanoate,butylene glycol,biosaccaride gum-1,peg-40 hydrogenated caster oil,ethylhexyl menthoxycinnamate,phenoxyethanol,potassium cetyl phosphate,macadamia ternifolia seed oil,dimethicone,carbomer,propylene glycol,glyceryl stearate,cocoglycerides,butyrospermum parkii,c12-13 alkyl lactate,methylparaben,benzophenone-3,pentadecalactone,sorbic acid,citrus aurantium dulcis oil,sodium hydroxyde,tocopheryl acetate,disodium edta,iris germanica root extract,retinyl palmitate,equisetum arvense extract,butylparaben,peg-8,propylparaben,ethylparaben,sodium hyaluronate,chlorhexidine digluconate,citrus aurantium amaraoil,tocopherol,ascorbyl palmitate,citric acid,ascorbic acid,limonene,linalool

水，c12-20 acid peg-8 ester，辛基十二烷醇，鲸蜡硬脂醇异壬酸酯，丁烯二醇，多醣物质，PEG-40氢化蓖麻油，4-甲氧基肉桂酸-2-乙基己基酯，苯氧乙醇，十六烷基磷酸钾，澳洲胡桃子油，地美司康，卡波姆，丙烯乙二醇，甘油硬脂酸，椰油脂酸甘油酯类，牛油果，c12-13烷醇乳酸酯，对羟基苯甲酸甲酯，二苯甲酮-3 ，环十五内酯，山梨酸，甜橙油，氢氧化钠，维生素E醋酸酯，乙二胺四乙酸二钠，鸢尾花萃取，维他命A酯，问荆萃取，对羟基苯甲酸丁酯，聚乙二醇- 8，羟苯丙酯，羟苯乙酯，透明质酸钠，洗必泰葡萄糖酸盐，苦橙油，维生素E ，维生素C棕榈酸酯，柠檬酸，抗坏血酸，柠檬精油，沉香醇水：几乎所有护肤品成分第一位都是水。辛基十二烷醇：界面活性剂、乳化剂、稠化剂，有一定刺激性

Prophenoloxidase is a key enzyme for mediating melanotic encapsulation of oocysts,which may be transformed into active phenoloxidase by limiting proteolysis.

而前酚氧化酶(Prophenoloxidase，PPO)是介导卵囊黑化包被反应的一种关键酶，活化后可催化酪氨酸羟基化为二羟基苯基丙氨酸，二羟基苯基丙氨酸和多巴胺可进一步氧化为具有活性的苯醌活性，苯醌即可介导蛋白交联并聚合成黑色素层固定、隔离或杀死入侵的病原体。

According to the invention, the natural substances in question are selected from: hydroxy-cinnamic acids and the esters and depsides thereof; plant phenols which can be derived from hydroxy-cinnamic acids; polymers of hydroxy-cinnamic alcohols; other natural substances of plant origin which have anti-mutagenic and aromatising properties and are combined with anti-oxydant vitamins or with the precursors and/or derivatives thereof; and other anti-oxidant vitamins which are made to form complexes with eucaryotic cell cultures.

按照本发明，这些天然物质选自羟基肉桂酸及其酯和缩酚酸、可以由羟基肉桂酸衍生得到的植物酚、羟基肉桂醇的聚合物、具有抗诱变性和芳化性质的并且与维生素合用的其他植物源天然物质、以及与真核细胞培养物络合的其他抗氧化性维生素。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。