羟基酸

The analogs of piracetum with the core of demethylclausenamide(III-4 and III-5) were prepared by condensation of demethylclausenamide with ethyl bromoacetate and hydrolysis or aminolysis there after.

3在兰培工作的基础上，选用O-乙酰-R--扁桃酸为拆分剂，成功的拆分了表黄皮酰胺前体5--4-苯基-1-甲基吡咯烷酮(Ⅱ-1)，和Ⅱ-1分别引入3位羟基得到和表黄皮酰胺。

Objective To study antioxidation ofDi-(3β-hydroxyandrost-5-en-17-one) ester, a new compound which was structure derivated from active substance from Asterias amurensis.

目的 以兔和大鼠心肌及肝组织匀浆为材料，研究一种从多棘海盘车中提取得到的活性物质经结构改造和修饰得到的丁二酸二-（3β-羟基雄甾5-烯-17-酮）酯新化合物抗脂质过氧化作用。

Study on the Modification of Poly (3-hydroxyalkanoate) The aim of this dissertation is to modify bacterially produced poly (3-hydroxybutyrate) and its copolymer with 3-hydroxyvalerate .

本论文目的是改性细菌合成的聚（3-羟基丁酸酯）及其共聚物，采用交联或共混的方法，改变其聚集态结构或超分子结构，从而改善其力学性能。

A novel liquid crystalline compound named p-phenylenediamine di 4-[2- benzamide] was synthesized from allyl 2-hydroxyethylether, ethyl 4-hydroxybenzoate and p-phenylenediamine.

以乙二醇单烯丙基醚、对羟基苯甲酸乙酯、对苯二胺为原料合成了末端为不饱和双键的芳香聚酰胺溶致型液晶化合物——二对烯丙氧基乙氧基苯甲酰对苯二胺，最佳合成的摩尔比为∶羧酸∶对苯二胺∶吡啶=2。

Factories strong technical force, advanced production equipment, production of meglumine, Portugal TOA, benzylamine and its family of products, sesame phenol, quetiapine fumarate major intermediate, 4 - hydroxy droperidol, and other products sold at home and abroad.

工厂技术力量雄厚，生产设备先进，生产的葡甲胺、葡辛胺、苄胺及其系列产品、芝麻酚、富马酸喹硫平主要中间体、4-羟基哌啶等产品远销海内外。

To improve water solubility of betulin, two acyl groups were introduced at C-3 and C-28 hydroxy groups of betulin. 3, 28-di-O-glutaryl-betulin was synthesized with pyridine as solvent and DMAP as catalyst from betulin and glutaryl anhydride.

为了增强桦木醇的亲水性，对桦木醇的C-3位、C-28位羟基进行修饰，在吡啶作溶剂、二甲基氨基吡啶作催化剂的条件下，与戊二酸酐反应合成桦木醇戊二酸酯。

Abstract〕 Objective To study 23-hydroxyl betulinic acid induced apoptosis and growth inhibition of B16 melanoma cell in vivo and in vitro.

摘要〕 目的研究23-羟基桦木酸对体内、外B16黑色素瘤细胞生长的抑制及诱导凋亡作用。

Key words〕 23-hydroxyl betulinic acid;B16 melanoma cell;apoptosis

关键词〕 23-羟基桦木酸；黑色素瘤细胞；细胞凋亡

Methods MTT assay,electronic microscopy,flow cytometry and tumor volume assay were used to examine the effect of 23-hydroxyl betulinic acid on B16 melanoma cell line.

应用MTT分析，电镜观察，流式细胞仪，肿瘤体积大小测定等方法，对23-羟基桦木酸诱导黑色素瘤细胞进行检测和观察。

Results 30～80μg/ml 23-hydroxyl betulinic acid in vitro and 300mg/kg～600mg/kg P.O.in vitro markedly inhibited the growth of B16 cells at a dose-dependent manner with a great number of apoptotic cells seen.

结果 23-羟基桦木酸体外30～80μg/ml处理，体内300mg/kg～600mg/kg灌胃时，对B16细胞有显著的生长抑制作用，有一定的剂量依赖关系并出现大量的凋亡细胞，同时体内肿瘤细胞被阻滞在G0～G1期，DNA合成受阻，肿瘤体积缩小。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。