羟基酮

The present invention belongs to the technical field of biological pharmacy, and in particular relates to a preparation and purification method of tetra-hydroxyl xanthone mango aglycone, and an application thereof in hypoglycemic medicine.

本发明属于生物制药技术领域，具体涉及一种四羟基口山酮芒果苷元的制备、纯化以及其在降血糖药物中的应用。

The nutritional and environmental conditions for acetoin product ion from Bacillus licheniformis in flasks were studied in this manuscript.

初步研究了摇瓶条件下地衣芽孢杆菌发酵生产3-羟基－2-T酮的工艺条件。

Then fed-batch fermentation was performed with glucose feeding. The yield of acetoin achieved at 20 g/L in fed-batch fermentation with glucose feeding.

在优化的发酵条件下，采用分批补糖的工艺，摇瓶发酵产量可稳定在20g/L以上，为3-羟基－2-丁酮的工业化生产提供了一定的基础。

It shown that PDC does not only catalyze the production of acetaldehyde (PDC's main activity), but also catalyzes an aldoltype condensation reaction in which the hydroxyethyl-ThDP intermediate of enzyme is condensed with a second acetaldehyde to form acetoin.

在研究中发现PDC不仅能催化产生乙醛，还具有醛连接酶的活性。即将二个乙醛分子缩合成3-羟基丁酮，尽管这个活性比产生乙醛的活性低得多。

LacZ gene was fused with the promoter of the acoR gene and bkdR gene, and two recombined genes were expressed in sigL mutant strain and HD-73 wild strain sequentially.

分别将调控aco操纵子（编码3-羟基丁酮脱氢酶系统）的转录调节基因acoR和调控bkd操纵子（编码催化支链脂肪酸合成的酶系统）的转录调节基因bkdR的启动子与lacZ基因融合，并转入出发菌株和sigL突变体中，测定b-半乳糖苷酶的活性。

Results Six compounds were isolated from the ethanol extracts of Acrostichum aureurm,and their structures were elucidated as ponasterone A(1),pterosterone(2),kaempferol(3),quercetin(4),4-(3,4-dihydroxyphenyl)-2-butanone(5),and daucosterol(6),respectively.

结果从卤蕨乙醇提取物中分离得到6个化合物，分别鉴定为ponasterone A(1)、pterosterone(2)、山奈酚(3)、槲皮素(4)、4-(3，4-二羟基苯基)-2-丁酮(5)、胡萝卜苷(6)。结论6个化合物均为首次从该植物中分离得到。

Water,dimethicone,propylene glycol,glycerin,cyclomethicone,ppg-15 stearyl ether,sorbitan oleate,stearic acid,cetyl alcohol,glyceryl stearate,ethylhexyl methoxycinnamate,peg-100 stearate,panthenol,phenoxyethanol,phospholipids,triethanolamine,methylparaben,oenothera biennis oil,imidazolidinyl urea,carbomer,c12-13 alkyl lactate,glycyrrhetinic acid,citrus aurantium dulcisoil,propylparaben,tocopheryl acetate,benzophenone-3,triclosan,disodium edta,ethylparaben,pentadecalactone,iris germanica root extract,retinyl palmitate,bisabolol,butylparaben,sodium hyaluronate,aesculus hippocastanumseed extract,ruscus aculeatus root extract,chlorhexidine digluconate,biosaccharide gum-1,citrus aurantium amaraoil,tocopherol,lecithin,ascorbyl palmitate,glyceryl oleate,BHT,citric acid,limonene,linalool

水， 地美司康，丙二醇，甘油，环甲硅脂， PPG-15 硬脂基醚，油酸己六酯，硬脂酸，十六醇，甘油硬脂酸， 4-甲氧基肉桂酸-2-乙基己基酯，聚乙二醇硬脂酸酯，维生素B5，苯氧乙醇，磷脂质，三乙醇胺，羟苯甲酯，月见草油，尿素醛，卡波姆， c12-13烷醇乳酸酯，甘草亭酸，甜橙油，羟苯丙酯，醋酸盐维他命E，二苯酮-3，玉洁新，乙酸乙二胺二钠，羟苯乙酯，环十五内酯，鸢尾花根萃取，维他命A酯，没药醇，羟苯丁酯，透明质酸钠，欧洲七叶树籽萃取，假叶树根萃取，洗必泰葡萄糖酸盐，多醣物质，苦橙油，维生素E，卵燐脂，抗坏血酸棕榈酸酯，甘油油酸酯，二丁基羟基甲苯，柠檬酸，柠檬精油，芳樟醇水：几乎所有护肤品成分第一位都是水。地美司康：即silicon，矽灵，一般添加于霜剂中，使用后皮肤手感光滑。该成分不可吸收。

The analogs of piracetum with the core of demethylclausenamide(III-4 and III-5) were prepared by condensation of demethylclausenamide with ethyl bromoacetate and hydrolysis or aminolysis there after.

3在兰培工作的基础上，选用O-乙酰-R--扁桃酸为拆分剂，成功的拆分了表黄皮酰胺前体5--4-苯基-1-甲基吡咯烷酮(Ⅱ-1)，和Ⅱ-1分别引入3位羟基得到和表黄皮酰胺。

2-Substituted-3,4-dihydro-1(2H)-isoquinolinones were synthesized from methyl 3-hydroxy-ben- zoates via allyl etherification, Claisen rearrangement, oxidation, reductive amination and aminolysis for the first time.

以3-羟基-4-甲氧基苯甲酸甲酯等为原料，通过烯丙基醚化、Claisen重排、氧化、与伯胺反应、还原、分子内酯的胺解六步反应合成了一系列2-取代-3，4-二氢-1-异喹啉酮类化合物。

C. Antioxidizer and light stabilizer: the antioxidizer has many varieties, including antioxidizer 3114, BHT, antioxidizer 1010, antioxidizer 1076, Tiunin 770, TPP, TNP; the additive amount is usually below 20mg/kg.

c、抗氧剂和光稳定剂：抗氧剂的种类很多，抗氧剂3114，BHT，抗氧剂1010，抗氧剂1076，Tiunvin 770，TPP，TNP，添加量一般在20mg/kg 以下。2－羟基－4－正丁锌氧基二苯甲酮为紫外光吸收剂。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。