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羟基苯

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The new methods to synthesize 6-hydroxy-3, 8-dioxabicyclo[3.2.1]octane, dihydrobenzofuran and benzofuran derivatives are described in this thesis.

本文主要论述了(5R)-6-羟基-3,8-二氧二环[3.2.1]辛烷,苯并二氢呋喃和苯并呋喃类衍生物的合成新方法。

In the precence of the base catalyst KF/Al2O3, the one - pot reaction of 2 -hydroxybenzaldehyde or 2 - hydroxynaphthaldehyde with ethyl α- bromoacetate,α-bromoacetophenone , 1,4 - dichloromethylbenzene , 4,4'- dichloromethylbiphenyl and 1,5 -dichloromethylnaphthalene gave the benzofuran compounds in 38-89% yield.

本文报道用 KF/Al_2O_3作为碱催化剂,由水杨醛或2-羟基-1-萘醛分别和α-溴代乙酸酯、α-溴代苯乙酮、苄基氯、4,4'-二氯甲基联苯和1,5-二氯甲基萘等进行一锅化缩合反应,以38~89%的产率合成了14种芳并呋喃化合物。

Ethyl 4-[(1-hydroxy-1-methyl)ethyl]-2-propyl-1H-imidazole-5-carboxylate,the key intermediate of Olmesartan ,was synthesized from butanoic acid and o-phenylenediamine via condensation under microwave-irradiation,oxidation,esterification and the Gringard reaction.

用正丁酸与邻苯二胺为原料,在微波照射下缩合成2-丙基苯并咪唑,再氧化开环制得2-丙基咪唑二羧酸,再经酯化、Gringard反应制得抗高血压药物奥美沙坦的关键中间体2-丙基-4-[(1-羟基-1-甲基)乙基]-1H-咪唑-5-羧酸乙酯,总收率32.2%。

Water,glycerin,rosa centifolia flower water,butylene glycol,centaurea cyanus flower water,peg-40 hydrogenated castor oil,propylene glycol,ppg-26-buteth-26,phenoxyethanol,methylparaben,sorbic acid,benzophenone-4,pentadecalactone,citrus aurantium dulcisoil,panthenol,menthyl lactate,sodium hydroxide,glycyrrhiza glabraroot extract,aesculus hippocastanumseed extract,citrus aurantium amaraoil,allantoin,limonnene,linalool,blue 1(ci 42090),yellow 5ci 19140

水,甘油,千叶蔷薇花水,丁烯二醇,矢车菊花水,PEG-40氢化蓖麻油,丙二醇,PPG-26-丁醇聚醚-26,苯氧乙醇,对羟基苯甲酸甲酯,山梨酸,二苯甲酮-4,环十五内酯,甜橙油,泛醇,乳酸孟酯,氢氧化钠,甘草根萃取,七叶树籽萃取,苦橙油,尿囊素,柠檬精油,芳樟醇,蓝,黄水:几乎所有护肤品成分第一位都是水。

The results show that:Changing the substituents of the phenyl rings,on the one hand,will influence the capacity of conjugation of the phenyl rings through S→N dative bond and furthermore influence the weak acid-dissociation of phenolic hydroxyl,on the other hand,will influence the geometric conformation of the compound and furthermore influence to form structure matched with membrane and water/membrane.

结果表明:改变药物化合物两边苯环上的取代基,一方面,将影响苯环通过S←N授受键的共轭能力,进一步影响酚羟基的弱酸离解常数;另一方面,将影响C-S,S-N键自由旋转的难易程度,进一步影响到能否形成与膜/水膜界面相匹配的结构。

DMBQ, resorcin, ferulic acid, and hydroxybenzoic acid were effective chemical signal substances in the inducement of haustorium, but the haustorium formation rate was only 3.3%.

适当浓度的2,6-二甲氧基对苯醌、间苯二酚、阿魏酸和对羟基苯甲酸均可诱导肉苁蓉种子萌发形成吸器,吸器形成率最高为3.3%。

Hydroxy benzene acetic acid and acetic acid have biological activity, such as anti-bacterial and other aspects, a wide range of applications.

苯羟基乙酸和苯氧乙酸都具有生物活性,在诸如抗菌等方面具有广泛的应用。

The thermal behavious and structure of p(hydroxybenzoic acid/2-hydroxy-6-naphthoicacid)polyarylate /polyester blend fibers were investigated by means of DSC thermal analysis.

利用热分析的方法对聚(对羟基苯甲酸/6-羟基-2-甲酸萘[p(HBA/HNA]/聚对苯二甲酸乙二酯共混纤维的结构进行了研究。

Feeding for 24h by third instar larvae of the maize stalk borer induced farnesyl pyrophosphate synthase gene expressing, but had no effect on expression of AOC, BX9, PAL and PR2a genes and DIMBOA content.

3玉米螟3龄幼虫处理24h能诱导玉米根中法呢烯基焦磷酸合成酶基因表达,但不能诱导丙二烯氧化物环化酶、β-1,3葡聚糖酶基因(PR2a)、糖基转移酶(BX9)、苯丙氨酸转氨酶基因表达,同时对第二叶和根中丁布含量无显著影响,使第二叶对羟基苯甲酸及第三叶丁布、对羟基苯甲酸、香草酸含量显著降低。

This research utilized the method of organic synthesis, researching different amounts and positions of hydroxy-substituted benzoic acid and serotonin into amide reaction, so as to produce a series of polyhydroxy substituted N-benzoylserotonin derivatives (compound 1-10). Accordingly, this study conducts the following four tests. I. The activity of antioxidant and the experiment of ability to scavenge DPPH free radical, II. The ability of overall antioxidant—the activity of TEAC, III. The activity test of inhibit Tyrosinase, and IV. The study of absorbing UV / VIS Spectrophotometers. This study use trolox, arbutin, and octyl salicylate as the control groups, and to test the ability of anti-oxidation, the activity of inhibit Tyrosinase, and the ability of absorbing UV. This research ultimately intends to investigate the applied value of those compounds into cosmetics.

本研究主要利用有机合成的方法,将不同数量及不同位置的羟基取代苯甲酸化合物与色洛冬宁进行醯胺化反应后,得到一系列的多羟基取代之N-色洛冬宁苯甲醯胺衍生物(化合物1 ~ 10),进行四种不同活性测试方法:一、清除DPPH自由基能力抗氧化活性测试;二、总抗氧化能力活性测试;三、抑制酪胺酸酶活性美白测试;四、紫外线/可见光光谱仪吸收测试,并以水溶性维生素E、熊果素、水杨酸辛酯当作对照组,探讨其抗氧化能力、抑制酪胺酸酶的活性能力与吸收紫外线能力,再进一步探讨其应用於化妆品上的价值。

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