羟基苯

Ophenyl phenol,ophenyl phenol sodium salt tetrahydrate,7ADCA,2ethyl phenyl hydrazine hydrochloride,2,3dihydrofuran,7ethyl3(2hydroxy ethyl)indole,methyl ester of etodolac; 1,8diethyl1,3,4,9tetrahydropyrano[3.4b] indole1acetic acid methyl ester,5chloro2methoxy benzoic acid,4(2aminoethyl)benzene sulfonamide,5cyano phthalide,phthalhydrazide,9thioxanthenone,n[(1,4benzodioxane2yl)carboxyl]piperazine HCL,2chloro4amino6,7dimethoxyquinazoline,2chloro benzimidazole,1(4fluorobenzyl)2chlorobenzimidazole,2methylthio4pyrimidone,5amino4imidazole carboxamide HCL,6chloro2hexanone,11oxo6.11hydrodibenzothiepin,6,11dihydrodibenzooxepin11one,10,11dihydrodibenzocyclohepten5one;dibenzosuberone,dibenzo cyclohepten5one;dibenzosuberenone,3,5dihydroxy benzoic acid,3,5dihydroxy benzyl alcohol,2mercapto benzimidazole,3,4dihydroxy benzaldehyde,3,4dihydroxy benzonitrile,2amino5chloro benzonitrile,2(4chlorophenoxy)ethyl chloride,2(4chloro phenoxy)tert,butane,ditrimethylol propane;DTMP,2,2bis(4hydroxyphenyl)butane; bisphenol B,1,1'bis(4hydroxyphenyl)cyclohexane;bisphenol Z,tetrabromobisphenolS,3,5ditertbutyl salicylic acid,3,4,5trihydroxy benzoic acid stearyl ester,1,2,4trimethoxybenzene.

华业公司产品：邻苯基苯酚，邻苯基苯酚钠盐，7氨基3去乙酰氧基头孢烷酸，邻乙基苯肼盐酸盐，2，3二氢呋喃，7乙基色氨醇，依托度酸甲酯，5氯2甲氧基苯甲酸，4(2氨乙基)苯磺酰胺，5氰基苯酞，双酮酞嗪，9噻吨酮，N〔(1，4苯并二恶烷2基)羰基〕哌嗪盐酸盐，2氯4氨基6，7一二甲氧基喹唑啉，2氯苯并咪唑，1(4氟苄基)2氯苯并咪唑，2甲硫基4嘧啶酮，5氨基咪唑4 甲酰胺盐酸盐，6氯2已酮，11氧6.11二氢苯并〔b.c〕虑平，11氧代6，11二氢二苯并氧杂卓，10，11二氢二苯并环庚烯5酮，二苯并环庚烯5酮，3，5二羟基苯甲酸，3，5二羟基苯甲醇，2巯基苯并咪唑，3，4二羟基苯甲醛，3，4二羟基苯腈，2氨基5氯苯腈，2(4氯苯氧基)1氯乙烷，2(4氯苯氧基)叔丁烷，双丙烷，2，2二(4羟基苯基)丁烷；双酚B，1，1'双(4羟基苯基)环己烷；双酚Z，2[3，5二溴4(2，3二溴丙氧基)]苯砜，3，5二叔丁基水杨酸，3，4，5三羟基苯甲酸十八烷基脂，1，2，4三甲基氧基苯。

Their structures were characterized as dihydroconiferyl dihydro-p-coumarate, vanillin, apocynin, p-hydroxybenzaldehyde, syringaldehyde, syringic acid, syringylethanone,α-hydroxypropiosyringone, coniferyl aldehyde, dihydroconiferyl alcohol, 2-hydroxyphenylpropanol, and 3-hydroxy-4-methoxy-phenylethanol, respectively.

结果 从该植物中分离得到12个酚性化合物，其结构分别为二氢松柏醇二氢对羟基桂皮酸酯，香草醛，罗布麻宁，对羟基苯甲醛，丁香醛，丁香酸，丁香乙酮，α-羟基丁香丙酮，松柏醛，二氢松柏醇，2-羟基苯丙醇和3-羟基－4-甲氧基苯乙醇。

Methods 4-Hydroxybenzonitrile (2) as the starting material was transformed to 4-hydroxy-thiobenzamide (3) via thioformylation. And ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (4), which was synthesized via cyclization from 3, was treated with hexamethylenetetramine to generate the intermediate ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (5). The target compound febuxostat (1) was obtained from 5 by etherification, cyanidation, hydrolysis.

以羟基苯腈为原料，经硫代甲酰化得到对羟基硫代苯甲酰胺(3)，3经环合得到2-（4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(4)，4与乌洛托品反应，得到中间体2-（3-甲酰基－4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(5)，之后再经醚化、氰化、水解得到目标产物(1)。

Eight hydrazone Schiff bases have been synthesized by the reaction of salicylaldehyde, o–vanillin, 2-hydroxy-1-naphthaldehyde with nicotinic or isonicotinoyl hydrazide in anhydrous ethanol respectively; Three thiosemicarbazone Schiff bases have been synthesized by the reaction of salicylaldehyde, o–vanillin, o–hydroxyacetophenon with thiosemicarbazide in hydrous-ethanol respectively.

主要包括以下五部分的工作： 1、以水杨醛、邻香草醛、邻羟基萘甲醛、邻羟基苯乙酮分别与烟酰肼和异烟酰肼按1：1的比例在无水乙醇中反应，制备了八种酰腙类Schiff碱；以水杨醛、邻香草醛、邻羟基苯乙酮与氨基硫脲在水-乙醇混合溶剂中反应，合成了三种Schiff碱配体，并对Schiff碱配体的结构进行了表征。

The total synthese three natural compounds to explore enantioselective synthesis of flavanol: We use phloroglucin and 2, 4, 6-trihydroxyacetophone as starting materials to synthesis distenin in two ways; Resorcin was used to synthsis 2, 5-dimethoxymethoxyacetophone though 3 steps.

对黄烷醇化合物的立体选择性全合成进行了探索：以间苯三酚和2，4，6-三羟基苯乙酮为原料，尝试用两条路线对Distenin化合物进行了全合成研究；以对苯二酚为原料，经三步制得2，5-二甲氧甲氧基苯乙酮，与2，4，6-三甲氧甲氧基苯甲醛反应，经四步反应得到天然产物3，5，7，2′，5′-二五羟基黄烷关键中间体1-（2′，6′-二甲氧甲氧基苯）-3-（2"，4"，6-三甲氧甲氧基苯）丙烷-1R，2R-二醇83及其对映体84；简要介绍了EGCg类化合物的生物活性和研究概况。

Our scientific research, development, production, operating in one, are specializing in the production of pharmaceutical intermediates business, main products has L p-hydroxyphenylglycine Deng sylvite, L-p-hydroxyphenylglycine, L-annual production of 1,000 tons of p-hydroxyphenylglycine, L-leucine p-Tang Sylvite 1500 tons, sold more than the national pharmaceutical companies have some products for export and domestic enterprises set up a long-term and stable cooperative relations high-quality products in order to win the praise of the vast number of users.

我公司集科研、开发、生产、经营于一体，是医药中间体专业生产企业，主要产品有左旋对羟基苯甘氨酸邓钾盐、左旋对羟基苯甘氨酸，年生产左旋对羟基苯甘氨酸1000吨，左旋对羟基苯氨酸邓钾盐1500吨，销往全国多家药厂，已有部分产品出口，并与国内多家企业建立了长期、稳定的合作关系，以高质量的产品赢得了广大用户的赞誉。

Their structures were identified by physicochemical constant and spectral analysis (IR, UV, EI-MS, 1H-NMR, 13C-NMR, and HMBC). Results The compounds were identified from their ethanol extracts as: 6, 8-dihydroxy-2-[2-(3'-methoxy-4'-hydroxyl phenylethyl)] chromone and 6-methoxy-2-[2-(3'-methoxy-4'-hydroxyl phenylethyl)] chromone.

结果 从沉香乙醇提取物中分得2个色酮类成分，分别鉴定为6，8-二羟基－2-［2-（3'-甲氧基－4'-羟基苯乙基）］色原酮{6，8-dihydroxy-2-[2-(3'-methoxy-4'-hydroxyl phenylethyl)]chromone，Ⅰ}和6-甲氧基－2-［2-（3'-甲氧基－4'-羟基苯乙基）］色原酮{6-methoxy-2-[2-(3'-methoxy-4'-hydroxyl phenylethyl)]-chromone，Ⅱ}。

The total synthese three natural compounds to explore enantioselective synthesis of flavanol: We use phloroglucin and 2, 4, 6-trihydroxyacetophone as starting materials to synthesis distenin in two ways; Resorcin was used to synthsis 2, 5-dimethoxymethoxyacetophone though 3 steps.

对黄烷醇化合物的立体选择性全合成进行了探索：以间苯三酚和2，4，6-三羟基苯乙酮为原料，尝试用两条路线对Distenin化合物进行了全合成研究；以对苯二酚为原料，经三步制得2，5-二甲氧甲氧基苯乙酮，与2，4，6-三甲氧甲氧基苯甲醛反应，经四步反应得到天然产物3，5，7，2′，5′-二五羟基黄烷关键中间体1-（2′，6′-二甲氧甲氧基苯）-3-（2&，4&，6-三甲氧甲氧基苯）丙烷-1R，2R-二醇83及其对映体84；简要介绍了EGCg类化合物的生物活性和研究概况。

The phenyl acetate was synthesized from phenyl hydroxide and acetyl chloride by direct esterification and the factors influencing the synthesis were studied.Results showed that the optimal conditions were:n(C6H6O):n(C2H3OCl)=1:1.2,the amount of solvent cyclohexane was 40 mL(compared to 0.15 mol C6H6O),the reaction temperature was 20℃,and the reaction time was 5 h.

乙酸苯酯(分子式C8H8O2)是重要的药物中间体，它可以转化得到邻羟基苯乙酮和对羟基苯乙酮的混合物，可用于治疗急慢性黄疸型肝炎、胆囊炎等疾病，其中邻羟基苯乙酮是合成抗心律失常药盐酸普罗帕酮的重要中间体。

They are 2,7-dihydroxy-1,5,6-trimethoxy-9,10-phenanthrene,p-hydroxy phenyl aldehyde, 4-Hydroxybenzyl alcohol, Protocatechuic aldehyde, Gastrodin, 4,4'-Dihydroxydiphenylmethane,4-(4-(hydroxym-ethyl)phenoxymethylphenol,Isorhamnetin-3-O-glucoside,Isorhamnetin-3,7-di-O–glucoside, Imbricatin,2,3-dihydroxy-7-methoxy-9,10-dihydrophenanthropyrone, Cyclopholidone,Cyclopholidonol and β-daucosterol.

分别为：2，7-二羟基-1，5，6-三甲氧基-9，10-二氢菲，对羟基苯甲醛、天麻苷元、原儿茶醛、天麻素、4-（4-羟基-苄基）苯酚、4(4-苯氧基甲基苯酚、异鼠李素-3-O-葡萄糖苷、异鼠李素-3-O-7-O-二葡萄糖苷、Imbricatin、2，7-二羟基-3-甲氧基-9，10-二氢菲吡喃酮、Cyclopholidone、Cyclopholidonol和β-胡萝卜苷。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。