羟基化

Based on the problem of various types of catalyst and according to the features of carbonylation catalysts reactions, our team has been designed a series of new metal complexes of benimidazoles, which can be used for carbonylation catalyst of industry. Seven new benzimidazole derivatives were prepared by the o-phenylenediamine、oxalic acid、glycolic acid、monomethyl monopotassium malonate、ethyl cyanoacetate、succinic anhydride. The structures of them were confirmed by IR、Elemental analsis. The crystal structures of d and e were determined by X-ray single crystal diffraction of Germanic Bruker Smart APEX II CCD. The catalysis of them was tested by carbonylation reactions.

本文设计以邻苯二胺和草酸、羟基乙酸、丙二酸单甲酯、氰基乙酸乙酯、丁二酸单甲酯为原料采用PPA催化和无机酸催化法，合成了4种苯并咪唑-2-羧酸衍生物并进行了表征；培养了2个化合物d、e的晶体并测定和讨论了晶体结构；制备了3种未见报道的苯并咪唑金属配合物，对配合物在羰基化法制醋酐-醋酸反应的催化作用进行了初步试验。

OH radicals produced by ultrasound in aqueous solution attack phenolic cycle at adjacent or para position of the hydroxyl on phenol so that phenol is changed into small organic molecules such as muconic acid, maleic acid and ethane diacid. These small organic molecules will be oxidized to form carbon dioxide and water by.

苯酚超声降解的作用机理是，超声空化在水溶液中产生的·OH自由基进攻苯酚苯环上羟基的邻位或对位而使苯环断裂生成己二烯酸、顺式丁烯二酸和乙二酸小分子有机物而使苯酚得以降解，这些小分子有机物在·OH自由基的进一步作用下最终被氧化成CO〓和H〓O。

Method］(1)A new type of carbonated hydroxyapatite cementwas prepared. The powder of cement was composed of calcium carbonate, tricalcium phosphate and calcium phosphate dibasic.

［目的］应用无机化学材料合成碳酸化羟基磷灰石骨水泥，并通过发泡成孔的新方法制备能原位固化形成多孔结构的无机植骨材料。

A hyperbranched macromonomer (3) was synthesized with maleic anhydride,diethanolamine,o-phthalic anhydride by step polymerization,take advantage of the different activities of functional groups.

以顺丁烯二酸酐、二乙醇胺、邻苯二甲酸酐等为原料，利用官能团活性的差异，通过逐步展开的方法合成了含有双键和端羟基的聚型分子结构的超支化大单体(3)。

The first asymmetric total synthesis of coumarinolignoids Daphneticin and it's enantiomer was accomplished starting from 7-hydroxycoumarin and 3, 4, 5-trimethoxybenzaldehyde, in which Sharpless asymmetric dihydroxy reaction was used to construct chiral center, and Mitsunobu reaction was used to obtain desired configuration.

并以7-羟基香豆素和3，4，5-三甲氧基苯甲醛为起始原料，用Sharpless不对称双羟化反应构筑手性中心，用Mitsunobu偶联反应作为关键步骤，合成了手性的香豆素木脂素Daphneticin及其异构体。

Thiol groups were good to be used in functionalizing gold nanoparticles, and ester bond formation and breakage played the major role in this research. Thioctic acid and 11-mercapto-1-undecanol were used to functionalize the gold nanoparticles and form ester bond by using the carboxylic acid group on thioctic acid and the hydroxyl group on 11-mercapto-1-undecanol. Concentrated sulfuric acid was used to be the catalyst in this reaction, and sodium hydroxide was added for the proceeding of the reverse reaction.

硫醇官能基在金奈米粒子的修饰有很好的效果，利用带有硫醇官能基之tioctic acid 与11-mercapto-1-undecanol (11-MUDO)分子修饰在金奈米粒子上，并使TA上之羧基和11-MUDO上之羟基脱水生成酯化键，浓硫酸则是反应中的催化剂，而氢氧化钠则可促使系统进行逆反应。

The optimal conditions for the target product were obtained: reaction temperature 110 ℃, reaction time 1.5 h, NaOH dosage 1.2 g,molar ratio 3:1(disproportionated rosin glycide ester: the hydroxyl group per D-glucose unit), microwave power 700 W.

目标产物的最佳合成条件：反应温度110℃，反应时间1.5 h，NaOH用量1.2 g，摩尔比3：1（歧化松香缩水甘油酯：葡萄糖单元中羟基数）及微波功率700 W。

The latter is hydrolyzed in the acidic conditions, then the recovered copolymer of EO and glycidol with multi pending hydroxymethyls is esterified with 2-bromoisobutyrylbromide to produce the ATRP macroinitiator with multi pending bromoisobutyryl groups .

共聚物poly的羟基与2-溴异丁酰溴进行酯化反应，得到侧链挂有2-溴异丁酸酯基结构的可以用于原子转移自由基聚合体系的大分子引发剂Poly_

The pegylated polylactide-poly glycolide nanoparticle, whose surface was co-modified withmaleimide-polyethylene glycol and methoxy-polyethylene glycol, was made by double-emulsion and solvent evaporation method andcovalently conjugated with thiolated lactoferrin via its maleimide functionalgroup.

第一章首先由复乳／溶媒蒸发法制备马来酰亚胺—聚乙二醇(Maleimide-PEG，MAL-PEG)和甲氧基聚乙二醇表面共修饰的聚乳酸-聚羟基乙酸纳米粒，然后通过其表面MAL-PEG与巯基化Lf共价连接而制备Lf-NP_。

Water, Sodium Laureth Sulfate, Cocamidopropyl Betaine, Cocamide MEA, Disodium Cocamphodiacetate, Sodium Lauryl Sulfate, PEG 40 Hydrogenated Castor Oil, Perfume, Sodium Chloride, Propylene Glycol, Quaternium 80, Methylparaben, Polyquaternium 10, Hydroxypropyl Guar Hydroxpropyltrimonium Chloride, Citric Acid, Diazolidinyl Urea, Tetrasodium EDTA, Polyquaternium 7, Propylparaben, Sodium Hydroxide, Panthenol, Persea Gratissima Oil, Penta Sodium Pentetate, Hedera Helix Extract, Bambusa Vulgaris Extract

水，月桂醇聚醚硫酸酯钠，椰油酰胺丙基甜菜碱，椰油酰胺MEA，椰油酰两性基二乙酸二钠，月桂醇硫酸酯钠，PEG 40 氢化篦麻油，香料，氯化钠，丙二醇，季铵盐-80，苯甲酸甲脂，聚季铵盐-10，羟丙基瓜尔胶羟丙基三甲基氯化铵，柠檬酸，重氮烷基咪唑脲，乙二氨四醋酸四钠，聚季铵盐-7，对羟基苯甲酸丙酯，氢氧化钠，泛酰醇，酪梨油，喷替酸五钠，常春藤萃取物，银竹萃取物。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。