羟基化

Aim To identify the drug-metabolizing enzymes involved in the hydroxylation of the new anti-inflammatory and anodyne imrecoxib.

目的 探讨新型抗炎镇痛药艾瑞昔布在人体内的羟基化代谢酶。

The probable reactions of the adamantane,for example halogenation , alcoholization, nitration and alkylation,are summarized.

文章从分子设计的角度综述了金刚烷可能发生的化学反应，如卤化、羟基化、硝化、烷基化等；同时探讨了金刚烷化学反应的机理，为金刚烷在精细化工领域的深层次应用打下基础。

Under these conditions, photodegradation of MO mainly involves three intermedial processes: demethylation, methylation and hydroxylation.

其中，最先发生的是脱甲基化反应，而生成产物最多的是羟基化反应。

Catalysts in three synthesis routes,the hydroxylation of 4-tert-butyl-phenol,the alkylation of pyrocatechol by tert-butyl alcohol and the alkylation of pyrocatechol by isobutene,were discussed in detail in terms of reaction conditions,catalysts,temperature,reaction time etc.

论述了对叔丁基苯酚羟基化法、邻苯二酚与叔丁醇烷基化法和邻苯二酚与异丁烯烷基化法生产对叔丁基邻苯二酚的合成路线的催化剂。

However the addition order of tartrate and phosphate on activity of enzyme adsorbed by goethite produced the greatest impact.

胶体表面类型（硅氧烷表面或羟基化表面）及阴离子配体对胶体表面负电荷的贡献量在酶的吸附及活性保持中的重要性；B阴离子配体后加入时酶的吸附量一般比配体先加入时的高；C）配体加入顺序对二氧化锰的影响最显著，对砖红壤和高岭石的居中；对针铁矿的次之；对黄棕壤的最小。D）乙酸或草酸加入顺序对高岭石上固定化酶比活性的影响最大，而酒石酸或磷酸则对针铁矿影响最大。

The result indicates thato-PD is converted to one trimer with ca.

羟基自由基抑制剂和氧合血红素物种抑制剂尿酸都不抑制该氧化反应，这些结果表明邻苯二胺的羟基化反应没有包括在其氧化过程中。

D limonene was distributed among the culture flasks (200 mg/L). The flasks were incubated at 28oC on a rotary shaker (r/min=120) for 5 days. On completion, the culture broth were successively extracted with EtOAc. The extract was quantitatively measured by gas chromatography mass spectrometry analysis, The results showed that biocatalytic reactions were comprised of oxidation, including hydroxylation and ketonization which occurred at different positions of the D limonene, as well as hydrogenation, hydrolyzation, esterification and cyclic cleavage. These bacteria strains possess the distinctive biocatalytic capacities towards the D limonene. A series of terpenoids, including sesqui , di and tri terpernoids were also observed,which was accounted for D limonene had influence on the metabolites of marine bacteria.

以2216E为培养基，添加200mg/L的柠檬烯，在28℃，以120 r/min摇瓶培养5 d，用乙酸乙酯提取培养液，经GC MS分析其转化产物，结果显示，这些细菌能在柠檬烯的不同位置进行羟基化、羰基化等，并伴随有还原、水解、酯化、开环等反应，但转化能力和转化程度不同；在产物中，还检测到系列结构不同的其它萜类：包括倍半萜、二萜以及三萜等，这些萜类化合物的产生跟柠檬烯的加入有关，说明柠檬烯能影响细菌代谢产物的产生。

In pH=2.0 sulfuric acid solution, 2,2′bipyridine, an almost nonluminescent compound was transformed into a highly fluorescent compound (λex=340 nm,λem=430 nm) when attacked by ·OH generated by Fenton reaction.

在酸性介质中，Fenton反应产生的羟基自由基能将几乎无荧光的2，2′-联吡啶氧化成强荧光物质，羟基化产物的最大激发和发射波长分别是340 nm和430 nm。

Co-expression of collagen genes and cDNAs encoding the subunits of prolyl hydroxylase has lead to the synthesis of completely hydroxylated, thermostable collagens.

胶原基因和编码羟化酶亚单位的 cDNAs 的共表达已经可以使胶原完全的羟基化并耐热。

A series of transition metals, transition metal oxides and composite metal oxides were investigated as catalysts for phenol hydroxylation. Twelve new types of phenol hydroxylation catalysts with good activity and application prospect were reported.

考察了一系列过渡金属氧化物、复合金属氧化物及金属作为苯酚羟基化作用催化剂的反应性能，筛选出12种具有良好活性与应用前景，尚未见文献报道的苯酚羟基化新型催化剂。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。