羟基化

The productions of glycin oxidation are complicated and the cost is high. The cyanogenesis is poisonous and unsafe.

国内外合成羟基乙酸的方法主要有甘氨酸氧化法、氰化法、醛类羧化法、甲醛和甲酸甲酯偶联法、草酸电解法、氯乙酸水解法等。

The diazotization condition of 4-methyl-1-ethyl-3-cyano-5amino-6-hydroxy-2-pyridone and coupling condition of its diazo salt were researched, and the structure of its diazo salt was confirmed.

研究了4-甲基-1-乙基-3-氰基-5-氨基-6-羟基-2-吡啶酮的重氮化反应及其重氮盐发生偶合反应的条件，确定了重氮盐的结构。

Chapter two: Using 5-(4-aminophenyl)-10,15,20-triphenylporphyrin as thestarting compound, the classical diazotization of aniline and the resulting reaction ofdiazo salts were applied to porphyrin for the first time, and a series of asymmetriclysubstituted meso-tetraarylporphyrins including 5-(4-chlorophenyl)-10,15,20-triphenylporphyrin, 5-(4-iodinphenyl)-10,15,20-triphenylporphyrin, 5-(4-cyanophenyl)-10,15,20-triphenylporphyrin, 5-(4-bisphenyl)-10,15,20-triphenylporphyrin and 5-(4-hydroxylphenyl)-10,15,20-triphenylporphyrin were synthesized.

第二章：在已合成的5-(4-氨基苯基)-10，15，20-三苯基卟啉基础上，首次将芳胺的重氮化及重氮盐反应应用于卟啉，合成了5-(4-氯苯基)-10，15，20-三苯基卟啉、5-(4-碘基苯基)-10，15，20-三苯基卟啉、5-(4-氰基苯基)-10，15，20-三苯基卟啉、5-(4-联苯基)-10，15，20-三苯基卟啉和5-(4-羟基苯基)-10，15，20-三苯基卟啉等一系列不对称取代的meso-四芳基卟啉。

This specific preparation methods including: parathion of the initial reaction in acid and zinc metal in the common under redox reaction, a product of the reduction of parathion - parathion, with the sodium nitrite in the cold under diazotization reaction, and bovine serum protein tyrosine on the o-hydroxy combination of the adult immune original and immune rabbit polyclonal antibody preparation.

本发明制备方法具体包括：以对硫磷为反应初始物，在酸和金属锌的共同参与下进行氧化还原反应，得对硫磷还原产物对氨基对硫磷，再与亚硝酸钠在低温下进行重氮化反应后，与牛血清蛋白酪氨酸上羟基的邻位结合，制备成人工免疫原，并免疫新西兰大白兔制备多克隆抗体。

Based on the molecular structures, sugar alcohols can be classified into Mono sugar alcohol (such as erythritol, xylitol, sorbitol and mannitol ) and Disaccharide alcohol (such as maltitol,lactitol and isomaltitol).

糖醇是醛糖或酮糖的羰基经氢化还原成羟基的多元醇；按其结构可分为单糖醇(如四元赤藓糖醇、五元木糖醇、六元山梨糖醇和甘露糖醇)，双糖醇(如麦芽糖醇、乳糖醇、异麦芽酮糖醇)。

Structure Design and Modification of Mannitol-polylactide Tissue Engineering Materials;2. Based on the molecular structures, sugar alcohols can be classified into Mono sugar alcohol (such as erythritol, xylitol, sorbitol and mannitol ) and Disaccharide alcohol (such as maltitol,lactitol and isomaltitol).

糖醇是醛糖或酮糖的羰基经氢化还原成羟基的多元醇；按其结构可分为单糖醇(如四元赤藓糖醇、五元木糖醇、六元山梨糖醇和甘露糖醇)，双糖醇(如麦芽糖醇、乳糖醇、异麦芽酮糖醇)。

In the scheme,the key reactions were Grignard reaction, dihydroxylation,S_N2 substitution of hydroxyl and epoxide under acidic conditions and etc.

合成过程中的关键反应为Grignard反应，双羟化反应，质子酸催化的羟基与环氧的S_N2亲核取代成环反应。

Using Hexamethylenetetramine as the catalyst and P-Hydroxyanisole as the inhibitor, glycidyl methacrylate were prepared by two-step method successfully.

本论文以六次甲基四胺为催化剂，对羟基苯甲醚为阻聚剂，采用酯化闭环两步法制备出甲基丙烯酸缩水甘油酯。

Methods:The target compounds were synthesized from acylation of polyethylene glycol to hydroxy group of ursolic acid by polymer polycondensation method.

通过高分子缩合的方法，将酰化的聚乙二醇接枝到熊果酸的羟基上，得到目标产物。

Double hydroxyurea in organic synthesis as a reducing agent efficient use of reagents can be used as the use of hydroxylamine.

双羟基脲在有机合成中作为高效还原剂使用，也可以作为羟胺化试剂使用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。