羟基化

Propargyl alcohol was protected by dihydrophran with the catalysis of PPTS ,and then reacted with Ethyl Mag bromide to prepare its corresponding Grignard reagent.

炔丙醇在 PPTS 催化下由二氢吡喃保护，与溴乙烷格氏试剂反应生成相应的格氏试剂，然后与氯甲酸甲酯反应得到羟基丁炔酸甲酯四氢吡喃醚，在 PPTS 催化下脱保护后进行甲磺酰化，由溴化钠进行溴取代后合成了4-溴-2-丁炔酸甲酯，总收率达53%。

In the first part, the prototropic hydroxy-oxo tautomerisms of 2 (1H)- pyridones/2-hydorxypyridines, one of the most important model systems in molecular biology, have been investigated with self-consistent reaction field method based on continuum model. The influence of the nature and position of substituent groups, the existence of intramolecular hydrogen bonding and tautomeric competition between 2-hydroxy and 4-hydroxy on the tautomeric equilibria have also been examined.

第一部分，首先从溶剂敏感的异构化性质入手，用基于连续介质的自洽反应场理论方法对一类重要的生化模型体系—2（1H）-吡啶酮／2-羟基吡啶互变异构体系进行了研究，系统地考察了取代基性质、取代基位置、分子内氢键的形成以及互变异构竞争的存在对异构化平衡的影响。

The morphology of the mineral dependents on the solution characteristics. The main component of mineral was hydroxyapatite containing a little of CO32- group which the Ca/P ratio is 1.53, similar to the major mineral component of bone tissue. The porosities of the mineralized and unmineralized 3-D porous PLGA were (84.86±8.52)% and(79.70±7.70)% respectively. The biomechanical strength was 0.784±0.156 N/mm2 in unmineralized PLGA and 0.858±0.145N/mm2 in mineralized PLGA.

结果：PLGA经碱性溶液水解处理后表面亲水性明显增强，在0.5倍SBF中仅有少量矿物沉积，在SBF及1.5倍SBF中矿化后表面可以形成明显的矿化物；矿化物的形态与矿化液的浓度有关；矿化物主要成分为羟基磷灰石，含有碳酸根成分，钙磷比为1.53，类似于人骨无机质。

The optimum technical parameters were obtained as follows:bromating temperature is 15℃,solvent is methyl arcohol, bromating agent is BrCl,the molar ratio of 4-hydroxy-benzaldehyde to BrCl is 1:1.15,reaction time is 2.5 hours.

其工艺参数优化如下：溴化时反应温度选择15℃，溶剂选择甲醇+乙酸甲酯，溴化剂选择氯化溴，对羟基苯甲醛与氯化溴之比为1∶1.15，反应时间选择2.5个小时，滴溴时间约半个小时。

High-pressure liquid chromatography was used to determine the retention time and integral area ratio of every esterified production.

对不同条件下合成的三羟基二苯甲酮酯化215感光剂进行高效液相色谱分析，确定了产物中各酯化产物的保留时间及其在产物中所占的积分峰面积比。

Phenolic agent in alkaline lignin separated fromthe the black liquid can result in a chain etherized reaction on cycloalkanes by alkaline distilling so as to make lignin change its property.

从蒸煮黑液中分离的碱木素苯环上的酚羟基可与环氧烷基胺发生醚化接枝反应，从而使木素胺化改性。

Enynes with an aryl ring at the alkyne give 2,3,9,9a-tetrahydro-1H-cyclopentanaphthalenes by a 5-exo-dig cyclization followed by a Friedel-Crafts-type ring expansion.

带有芳环的1，6-二烯体和炔作用，并通过5-exo-dig路径环化，再紧接着Friedel-Crafts扩环，可以得到2，3，9，9a-四羟基-1H-环戊二烯并萘。6-endo-dig途径的环化在一些例子中作为副反应被观察到，尽管，这在一些具体的反应中，是作为主反应出现的。

Because a part of hydroxyl group in methyl cellulose were substituted by trimethylsilyl group , the product could be dissolved in amounts of common organic solvents, such as chloroform, xylene and so on.

通过甲基纤维素与六甲基二硅亚胺的反应，成功地实现了对水溶性物质甲基纤维素醚三甲基硅化的改性；红外光谱验证了反应的发生，核磁共振氢谱确定了三甲基硅甲基纤维素的取代度；纤维素醚上的部分羟基被三甲基硅化后取得了在普通溶剂中的良好的溶解性，且随着取代度的增加，在非极性溶剂中的溶解性逐渐变好；通过热失重实验，对其热稳定性进行了测试。

The increasing singlets of protons from acetyl group of product were treated as a reporter of the reaction progress. The reaction yields are calculated by the HR/MAS NMR.

利用四个羟基未保护的Nα-Fmoc氨基酸和七种全乙酰化糖为原料，合成了28个糖基化Nα-Fmoc氨基酸，均用高分辨魔角核磁共振技术定量。

TOC removal lags behind 4-chlorophenol removal in the ·OH-induced oxidative systems, indicating radiolytic technology alone is not efficient in terms of mineralization; the presence of O〓 and alkaline conditions facilitate the mineralization process.

羟基自由基氧化体系中TOC的去除滞后于4-氯酚的去除，说明单独使用辐射方法，氯酚的矿化率不高；氧气及碱性条件有利于体系中4-氯酚的矿化。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。