羟基乙酸

Water,c12-20 acid peg-8 ester,caprylic/capric triglyceride,proplylene glycol,ppg-15 stearyl ether,chondrus crispus,iris germanica(orris extract/cells),centaurea cyanus,macadamia ternifolia,buxus chinensis,triethanolamine,potassium cetyl phosphate,butyrospermum parkii,c12-13 alkyl lactate,carbomer,phenoxyethanol,methylparaben,imidazolidinyl urea,glyceryl hydroxystearin,tocopheryl acetate.retinyl palmitate,sodium hyaluronate,biosaccharide gum-1,propylparaben,disodium edta,ethylparaben,pentadecalactone,hydroxystearic acid,tetradecyloctadecanoic acid,tetradecyleicosanoic acid,hexadecyleicosanoic acid,butylparaben,isobutylparaben,chlorhexidine digluconate,tocopherol,lecithin,ascorbyl palmitate,glyceryl stearate,glyceryl oleate,BHT,citric acid.

水，C12-20 酸 PEG-8酯，辛酸/癸酸三酸甘油酯，丙二醇，PPG-15 硬脂基醚，卡拉胶萃取，德国鸢尾花提取物/细胞，矢车菊提取物，澳洲坚果油，荷荷巴油，三乙醇胺，十六烷基磷酸钾，牛油果，c12-13烷醇乳酸酯，卡波姆，苯氧乙醇，羟苯甲酯，尿素醛，甘油羟基硬脂酸酯，醋酸盐维他命E，维他命A酯，透明质酸钠，多醣物质，羟苯丙酯，乙酸乙二胺二钠，羟苯乙酯，环十五内酯，羟基硬脂酸，十四烷基十八烷酸，十四烷基二十烷酸，十六烷基二十烷酸，羟苯丁酯，对羟基苯甲酸异丁酯，洗必泰葡萄糖酸盐，维生素E，卵磷脂，抗坏血酸棕榈酸酯，甘油硬脂酸，甘油油酸酯，BHT，柠檬酸。水：几乎所有护肤品成分第一位都是水。辛酸/癸酸三酸甘油酯：润滑剂、扩散剂，棕榈油/椰子油衍生物

Water,decyloleate,propylene glycol,stearic acid,glyceryl stearate,peg-100 stearate,iris germanica(orris extract/cells),chamomilla recutita,arctium majus,prunus dulcis,ceteareth-3, Triethanolamine,phenoxyethanol,methylparaben,imidazolidinyl urea,carbomer,c12-13 alkyl lactate,disodium edta,propylparaben,glyceryl hydroxystearate,cetyl esters,ethylparaben,pentadecalactone,cera microcristallina,trihydroxystearin,butylparaben,hydroxystearic acid,isobutylparaben,chlorhexidine digluconate,tetradecyloctadecanoic acid,tetradecyleicosanoic acid,tocopherol,lecithin,ascorbyl palmitate,glyceryl oleate,citric acid

水，油酸癸酯，丙二醇，硬脂酸，甘油硬脂酸，聚乙二醇硬脂酸酯，鸢尾花提取物/活细胞，洋甘菊萃取，牛蒡提取物，甜杏仁油，鲸蜡硬脂醇醚，三乙醇胺，苯氧乙醇，羟苯甲酯，尿素醛，卡波姆，c12-13烷醇乳酸酯，乙酸乙二胺二钠，羟苯丙酯，甘油羟基硬脂酸酯，十六烷基酯，羟苯乙酯，环十五内酯，微晶蜡，三羟基硬脂精，羟苯丁酯，羟基硬脂酸，对羟基苯甲酸异丁酯，洗必泰葡萄糖酸盐，十四烷基十八烷酸，十四烷基二十烷酸，维生素E ，卵磷脂，抗坏血酸棕榈酸酯，甘油硬脂酸，柠檬酸水：几乎所有护肤品成分第一位都是水。油酸癸酯：滋润、柔肤剂，并常添加于多种化妆品中作为溶剂

Chemiluminescent immunoassay is one of the advanced immunoassay ofnon-radioisotopic immunoassay because of its high sensitivity, wide dynamic range,high accuracy, stable labeled protein, full automation and extensive application field.CLIA using acridinium ester derivatives as chemiluminescent label has advantages oflow background, high signal-to-noise ratio, no need of catalyst and simpleluminescence system. Different aspects associating the DMAE·NHS-based CLIA were studied in thisthesis, including synthesis of acridinium ester, chemiluminescentcharacteristics of DMAE·NHS, labelling antibody or streptavidin with DMAE·NHS,two-site sandwich chemiluminescent immunoassay for TSH, two-sitesandwich chemiluminescent immunoassay involved biotin-streptavidinsystem for TSH, and competitive chemiluminescent immunoassay usingbiotin-streptavidin system for TT〓. The desired acridinium ester, DMAE·NHS, was synthesized according to thereference method with some modifications. The products were identified by IR, NMR,MS and elemental analysis. In our method, KOH was used in place of NaOH tosynthesize benzyl ester of 3,5-dimethyl-4-hydroxybenzoic acid,2',6'-dimethyl-4'-(n-succinimidyloxycarbonyl) phenyl-acridinium-9-carboxylate waspurified on a silica gel column with chloroform/ethylacetate(4:1, v/v) as eluent andfurther purified by triturating with hexane/acetone(2:1, v/v).

DMAE·NHS的合成是本论文的关键和难点，我们对文献方法进行改进：文献方法用氢氧化钠与3，5-二甲基-4-羟基苯甲酸反应制得3，5-二甲基-4-羟基苯甲酸钠，再用3，5-二甲基-4-羟基苯甲酸钠与苄氯作用制备3，5-二甲基-4-羟基苯甲酸苄酯，我们用氢氧化钾代替氢氧化钠，使合成取得成功；在合成2'，6'-二甲基-4'-苯基-吖啶-9-甲酸酯时，文献方法对粗产品进行两次硅胶柱层析纯化，第一次柱层析用氯仿／乙酸乙酯(4∶1，V∶V)作溶剂和淋洗剂，第二次柱层析用己烷／丙酮(2∶1，V∶V)作溶剂和淋洗剂，按照文献方法得到的不是所需要的化合物，我们只进行第一次柱层析纯化，然后用己烷／丙酮(2∶1，V∶V)进行研磨，过滤，洗涤，除去溶于己烷／丙酮(2∶1，V∶V)的部分，得到所需要的产品。

Ingredients: Water,Glycerin,Caprylic/Capric Triglyceride,Myristyl Myristate,Butyrospermum Parkii Butter,Glyceryl Stearate,Panthenol,Betaine,Dimethicone,Hydrolyzed Collagen,Allantoin,Polysorbate-60,Carbomer,Xa-nthan Gum,Parfum,Triethanolamine,Tocopheryl Acetate,Hyaluronic Acid,Methyl Paraben,Propyl Paraben,Creatine,Tetrasodium Edta,Phenoxyethanol,Caprylyl Glycol,Sorbic.

成分： 去离子水，甘油，辛酸/葵酸三甘油酯，肉豆蔻酸肉豆蔻酯，乳木果油，硬脂酸甘油酯，泛醇，甜菜碱，聚二甲基硅氧烷，水解胶原蛋白，尿囊素，聚山梨醇酯-60，卡波姆，汉生胶，香精，三乙醇胺，生育酚乙酸酯，透明质酸，对羟基苯甲酸甲酯，对羟基苯甲酸丙酯，肌酸，乙二胺四乙酸四钠，苯氧乙醇，辛二醇，山梨酸。

Serotonin (5-HT), its precursors tryptophan and 5-hydroxytryptophan (5-HTP), major metabolites 5-hydroxyindoleacetic acid (5-HIAA); and 3-methoxy-4- hydroxyphenylethylene glycol , homovanillic acid , the respective major metabolites of noradrenaline and dopamine were measured by a method of HPLC.

应用高效液相色谱法测定其中5—羟色胺（5-HT）系列代谢物：色氨酸、5-羟色胺酸（5-HTP）、5-HT、5-羟吲哚乙酸（5-HIAA）；多巴胺的主要代谢产物3-甲氧基-4-羟基苯乙酸；去甲肾上腺素的主要代谢产物3-甲氧基-4-羟基苯乙二醇等。

By using gas chromatography technique nine kinds of fragrance components(acetic aldehyde,ethyl acetate,ethanol,propyl acetate,3-hydroxy-2-butanone,acetic acid,furfural,metacetonic acid,2,3-butylene glycol)were measured quantitatively in different kinds of Shanxi overmature vinegar and the other kinds of vinegar.

应用气相色谱方法对山西老陈醋和其他种类醋的9种香气成分(乙醛、乙酸乙酯、乙醇、乙酸丙酯、3-羟基-2-丁酮、乙酸、糖醛、丙酸、2，3-丁二醇)进行了定性、定量测定，并用聚类分析、模糊综合评判、方差分析、回归分析的方法对实验结果进行了数理分析。

For further understanding the effect of the strain on K-bearing silicate mineral, an experiment with KO2 strain cultured in nitrogen-containing and nitrogen-free medium was conducted. By putting mineral powders into the medium and measuring the concentration of capsular polysaccharides, we concluded that the strain can accelerate the weathering rate of silicate minerals. The results showed that the polysaccharides secreted by the strain in the growth process could help the bacterial to adhere to the mineral surface effectively, and created the bacterium-mineral complex, which formed a mircro-enviorment avail the release of potassium. Another result was that there was higher level of Carbonic Anhydrase activity, which revealed that some exo-protein or enzyme produced by the bacterial had postive impact on the process of releasing potassium ion. We carried out the bacterial fermentation for larger scale production of the bacterial secretion, which was used to sperate, and identify the small molecules related to the mineral-bacterial interaction. After the analysis, it was found that the strain can produce many kinds of small molecules, such as 2-Hydroxybenzoic acid, 4-Hydroxyphenylacetic acid, methyl-4-hydroxybenzoate, etc.

分别将菌株接入含有不同矿粉的培养基中培养，检测其在有氮、无氮培养基中荚膜多糖含量的变化，并在以钾长石和黑云母为矿源的情况下，比较研究了菌株在有氮、无氮培养基中对矿物的风化能力，通过一系列的实验，证实胶质芽孢杆菌在生长过程中所分泌的粘稠胞外聚糖可帮助细菌有效黏附在矿物表面，形成细菌-矿物复合体，并改变及维持该复合体内部的微环境，有助于该菌的解钾作用，而且细菌分泌的胞外蛋白质在该菌对含钾硅酸盐矿物的解钾作用过程中发挥重要作用；将胶质芽孢杆菌接入以钾长石和黑云母为矿源的有氮、无氮培养基中培养，检测到该菌碳酸酐酶活性的变化，并进行批量发酵后小分子酸性分泌产物的提取、分离、纯化与鉴定等方面的研究，结果表明，该菌可产生2-羟基苯甲酸，4-羟基苯乙酸，4-羟基苯甲酸甲酯等小分子物质。

The products were identified by IR,NMR,MS and elemental analysis. In our method,K.OH was used in place of NaOH to synthesize benzyl ester of 3,5-dimethyl-4-hydroxybenzoic acid,2',6'-dimethyl-4'-(n-succinimidyloxycarbonyl) phenyl-acridinium-9-carboxylate was purified on a silica gel column with chloroform/ethylacetate(4:l,v/v) as eluent and further purified by triturating with hexane/acetone(2:l,v/v).The luminescence produced by DMAE-NHS is a flash light with maximumemission at 0.4s and decay half-time of 0.9s. The luminescence intensity is 6.11x10 cps/mol,which is affected by the composition of trigger and surfactant.

DMAE·NHS的合成是本论文的关键和难点，我们对文献方法进行改进：文献方法用氢氧化钠与3，5-二甲基-4-羟基苯甲酸反应制得3，5-甲基-4-羟基苯甲酸钠，再用3，5-二甲基-4-羟基苯甲酸钠与苄氯作用制备3，5-二甲基-4-羟基苯甲酸苄酯，我们用氢氧化钾代替氢氧化钠，使合成取得成功；在合成2'，6'-二甲基-4'-苯基-吖啶-9-甲酸酯时，文献方法对粗产品进行两次硅胶柱层析纯化，第一次柱层析用氯仿/乙酸乙酯(4：1，Ⅴ：Ⅴ)作溶剂和淋洗剂，第二次柱层析用己烷/丙酮(2：1，Ⅴ：Ⅴ)作溶剂和淋洗剂，按照文献方法得到的不是所需要的化合物，我们只进行第一次柱层析纯化，然后用己烷/丙酮(2：1，Ⅴ：Ⅴ)进行研磨，过滤，洗涤，除去溶于己烷/丙酮(2：1，Ⅴ：Ⅴ)的部分，得到所需要的产品。

The phenyl acetate was synthesized from phenyl hydroxide and acetyl chloride by direct esterification and the factors influencing the synthesis were studied.Results showed that the optimal conditions were:n(C6H6O):n(C2H3OCl)=1:1.2,the amount of solvent cyclohexane was 40 mL(compared to 0.15 mol C6H6O),the reaction temperature was 20℃,and the reaction time was 5 h.

乙酸苯酯(分子式C8H8O2)是重要的药物中间体，它可以转化得到邻羟基苯乙酮和对羟基苯乙酮的混合物，可用于治疗急慢性黄疸型肝炎、胆囊炎等疾病，其中邻羟基苯乙酮是合成抗心律失常药盐酸普罗帕酮的重要中间体。

Treatment of sucrose alkyl 4,6-orthoacetate hexaacetates I with water or alcohol in the presence of an acid catalyst afforded derivatives of sucrose acetates by selectively blocking specific hydroxyl group in sucrose and acetyl migration.

4，6-原乙酸蔗糖六乙酸酯在酸催化下水解和醇解，选择性地保护了蔗糖分子中的某些羟基，并通过乙酰基由C~4→C~6迁移的异构化反应合成了一系列蔗糖乙酸酯。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。