羟基乙酸

From Cacalia deltophylla (collected from Luqu County, Gansu Province), 22 compounds were isolated, of which 15 compounds have been identified. Among them, two compounds are new. They are named as 3-methyl-4-hydro-8-acetyl-furanonaphth-9-one and 1hydroxy-2-methoxy-3-acetyl-4, 8-dimethyl-5, 8-dihydro-naphthalene.

从采自甘肃省碌曲县的三角叶蟹甲草全草的甲醇提取物的石油醚部分和乙酸乙酯部分中，采用同样方法分离得到22个化合物，鉴定了其中的15个化合物，其中有2个为新化合物，分别命名为3-甲基-4-氢-8-乙酰基-呋喃萘-9-酮（2）和1-羟基-2-甲氧基-3-乙酰基-4，8-二甲基-5，8-二氢-萘（3）。

Analyse and compare what adopt a variety of pair of methods, the Michael addition reaction of ester of acerbity second of second of hydroxyl of protection of benzyl of the response of close nucleus addition that uses second nitrile and ester of formic acid second certainly, chloridize, cyanogen, reaction that take off carboxyl generates 3- benzyl oxygen radical the fifth of the ten Heavenly Stem the method of 2 nitrile, detailed discussion the action that wait and the by-product that arise possibly reach the reactant in each pace reaction, activator, dissolvent avoid a method.

通过对多种方法的分析和比较，确定采用乙腈和甲酸乙酯的亲核加成反应、氯化苄保护羟基、氰乙酸乙酯的Michael加成反应、脱羧反应生成3-苄氧基戊二腈的方法，并具体的讨论了每一步反应中反应物、催化剂、溶剂等的功能和可能产生的副产物及避免方法。

To synthesize the octreotide, Phe-Leu-Glu-Glu-Leu and C_(15)H_(31)-CO-Lys-Thr -Thr-Lys-Ser peptides, the strategies are as followings: Fmoc- group as protective group for α-NH_2; TBTU, DIEA and HOBt as coupling reagent; and ethanedithiol -phenol - thioanisole - H_2O - TFA ( 2.5:5:5:5:82.5 , V/V ) as cleaving solution.

采用Fmoc固相合成法，以苯并三哗四甲基脲四氟硼酸盐、二异丙基乙胺和1-羟基苯骈三氮唑为缩合剂；苯酚—乙二硫醇—苯甲硫醚—水—三氟乙酸(5：5：2.5：5：82.5，V/V)为切割试剂，合成了奥曲肽、Phe-Leu-Glu-Glu-Leu及C_(15)H_(31)-CO-Lys-Thr-Thr-Lys-Ser三种小分子多肽，并对奥曲肽的合成规模进行了放大。

Water, Sodium Laureth Sulfate, Cocamidopropyl Betaine, Cocamide MEA, Disodium Cocamphodiacetate, Sodium Lauryl Sulfate, PEG 40 Hydrogenated Castor Oil, Perfume, Sodium Chloride, Propylene Glycol, Quaternium 80, Methylparaben, Polyquaternium 10, Hydroxypropyl Guar Hydroxpropyltrimonium Chloride, Citric Acid, Diazolidinyl Urea, Tetrasodium EDTA, Polyquaternium 7, Propylparaben, Sodium Hydroxide, Panthenol, Persea Gratissima Oil, Penta Sodium Pentetate, Hedera Helix Extract, Bambusa Vulgaris Extract

水，月桂醇聚醚硫酸酯钠，椰油酰胺丙基甜菜碱，椰油酰胺MEA，椰油酰两性基二乙酸二钠，月桂醇硫酸酯钠，PEG 40 氢化篦麻油，香料，氯化钠，丙二醇，季铵盐-80，苯甲酸甲脂，聚季铵盐-10，羟丙基瓜尔胶羟丙基三甲基氯化铵，柠檬酸，重氮烷基咪唑脲，乙二氨四醋酸四钠，聚季铵盐-7，对羟基苯甲酸丙酯，氢氧化钠，泛酰醇，酪梨油，喷替酸五钠，常春藤萃取物，银竹萃取物。

This paper reported the synthesis of 2-hydroxyl-1-naphthalene formaldehyde under microwave irradiation with 2-naphthol, hexamethylenamine, solvent of glacial acetic acide, catalysis of sulphuric acid, and discussed the influence of the time and the power of microwave radiation, the proportion and quantity of reagents to the synthetic yield.

利用微波技术，采用2-萘酚与六次甲基四胺为原料，冰乙酸作溶剂，在浓硫酸的催化下合成2-羟基－1-萘甲醛，并考察了微波作用的时间、微波辐射功率、反应试剂的组成与用量等因素对产物产率的影响。

In the pretreatment group, Bak Foong Pill extracts were given for 14 days prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.

给予BFP预处理后，用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化；同时应用免疫组织化学法检测Bax蛋白表达；应用高效液相-电化学方法检测纹状体巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。

Methods The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 7-nitroindazole (7-NI) on nitric oxide synthase activity, levels of dopamine、3,4-dihydroxyphenylacetic acid、homovanillic acid, and TH-immunostained postive nerve fibres in the striatum of mice were determined by using colorimetic analysis, HPLC with electrochemical detection, and immunohistochemical analysis.

用比色分析、高效液相色谱电化学及免疫组化法检测1-甲基-4-苯基-四氢吡啶和7-硝基吲唑（7-NI）对C57BL小鼠纹状体一氧化氮合酶活性，多巴胺、二羟基苯乙酸、高香草酸水平和酪氨酸羟化酶免疫阳性神经纤维的影响。

In the pretreatment group, Bak Foong Pill extracts were given for 14 daya prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.

给予BFP预处理后，用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化；同时应用免疫组织化学法检测Bax蛋白表达；应用高效液相－电化学方法检测纹状体多巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。

Hours later,these mice were decapitated,and the striatums were isolated from thebrains. The levels of dopamine, serotonin ( 5-HT ), homovanillic acid, 5-hydroxyindoleacetic acid ( 5-HIAA ) andnorepinephrinein the striatum were measured by high-performance liquid chromatography with electrochemical detection.

给3组小鼠分别喂食Dieldrin 50 mg·kg-1体重、Dieldrin 40 mg·kg-1体重和等量的生理盐水，3 h后处死小鼠，取纹状体匀浆用高效液相色谱-电化学检测法测定纹状体中多巴胺、5-羟色胺(5-HT)、高香草酸、5-羟基吲哚乙酸(5-HIAA)和去甲肾上腺素的含量。

Immunohistochemistry technology was used to evaluated tyrosine hydroxylase of DA synthesis. DA, 5-hydroxytryptophan(5-HT) and their respective metabolic products 3,4 -dihydroxyphenylacetic, homovanillic are also precisely quantified in this research by using high-pressure liquid chromatography with electrochemical detector. The main metabolism monoamine oxidase of DA was processed too. RESULTS:WD can increase the synthesis and the metabolism process of DA .

本文观察了温胆汤及其配伍对大鼠刻板行为的影响，采用了免疫组化技术对多巴胺的合成酶—酪氨酸羟化酶进行了含量测定，应用高效液相-电化学法测定了DA、5-羟色胺（5-HT）及代谢产物3，4—二羟基苯乙酸、高香草酸的含量，并测定了DA主要降解酶—单胺氧化酶。

The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性，因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊，这是第二次你打败了我！