羟基

Methods 4-Hydroxy- benzonitrile was treated with sodium hydrogen sulfide and anhydrous magnesium chloride in dimethyl formamide to give thioamide, which was then directly cyclized with ethyl 2-chloroacetoacetate without separation to give ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(2) in one-pot; then 2 was formylated with Duff reaction adopting hexamethylenetetramine in trifluoroacetic acid to give ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(3); finally, the target compound was obtained by the treatment of 3 with hydroxylamine hydrochloride and sodium formate in formic acid.

采用&一勺烩&方法，以4-羟基苯甲腈为起始原料，首先与硫氢化钠和无水氯化镁在N，N-二甲基甲酰胺中反应，所得中间体不经分离，直接加入2-氯乙酰乙酸乙酯进行环合反应，得到2-(4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（2）；然后通过六亚甲基四胺/三氟乙酸进行Duff反应，得到2-(3-甲酰基-4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（3）；再经盐酸羟胺/甲酸/甲酸钠体系脱水得到目标化合物。

Triphenylmethyl chloride can react selectively with the 30-hydroxil group of glycyrrhetol under the catalyzing effects of three ethyl amine and dimethyl amino-pyridine.This condition of the reaction has an important value for the selective protection of 30-hydroxil group of glycyrrhetol.

三苯氯甲烷在三乙胺和二甲氨基吡啶等碱性催化下与甘草萜醇的C30-位羟基进行选择性缩合反应，此反应产率较与C3-位羟基化反应的要高，此种反应条件在甘草萜醇C30-位羟基的选择性保护中具有重要的价值。

The results showed that in the growth period of R. glutinosa, soil ferulic acid, vanillic acid, and vanillin contents had a persistent increase, while β-hydroxybenzoic acid content increased first but decreased then. The addition of ferulic acid (8 μg·ml-1), vanillic acid (08 μg·ml-1), vanillin (12 μg·ml-1), and β-hydroxybenzoic acid (30 μg·ml-1) in water culture had stronger inhibitory effects on R. glutinosa root length, root mass, fresh plant mass, and plant height. Treating with test phenolic acids except β-hydroxybenzoic acid increased leaf chlorophyll content significantly, compared with the control. After treated with test phenolic acids, plant SOD and POD activities decreased after an initial increase, and plant malondialdehyde content increased. In the treatment of ferulic acid, root SOD and POD activities were the lowest, and roots were rotted and dead.

结果表明：阿魏酸、香草酸和香草醛含量在地黄生长期表现为持续增加，而对羟基苯甲酸含量先升高后降低；外加阿魏酸（8 μg·ml-1）、香草酸（0.8 μg·ml-1）、香草醛（1.2 μg·ml-1）和对羟基苯甲酸（3.0 μg·ml-1）对水培地黄根长、根质量、全株鲜质量和株高有较强的抑制作用；酚酸处理使地黄叶片叶绿素含量降低，除对羟基苯甲酸外差异性极显著；经过酚酸处理的地黄幼苗SOD和POD活性为先升高后下降，丙二醛含量升高，其中阿魏酸的处理使根中酶活性降至最低，根部腐烂死亡。

The invention discloses an electrochemical method for preparing a hydroxylapatite particle thin coating on the surface of a metal implant, which comprises the following steps: electrolyte is put into a container equipped with a constant temperature heating system and heated to be 30 DEG C to 95 DEG C, and then the temperature is kept; platinum is taken as the anode and evenly distributed around the container, and the metal implant is taken as the cathode, put in the middle of the container and totally soaked in the electrolyte; DC voltage of 2V to 4V is added between the anode and the cathode, the surface of the metal implant has cathode reduction reaction, the pH value is increased and the supersaturation degree of the hydroxylapatite is also increased, so as to crystalize on the surface of titanium; after 0.5h to 5h of deposition, a layer of hydroxylapatite particle thin coating which can be excellently adhered to the matrix metal is formed on the surface of the implant.

本发明公开了一种在金属植入体表面制备羟基磷灰石颗粒薄涂层的电化学方法，在装备了恒温加热系统的容器中装入电解液，并将电解液加热到30～95℃恒温；将铂作为阳极均匀分布在容器四周，金属植入体作为阴极置于容器中间，完全浸没在电解液中，两极之间加直流电压2～4V，金属植入体表面发生阴极还原反应，pH值升高，羟基磷灰石过饱和度增加，从而结晶在钛金属表面；经过0.5～5小时沉积后，在植入体表面即可形成一层与基体金属结合优良的、薄的羟基磷灰石颗粒薄涂层。

Methane adsorbed on the Mn〓O〓-Na〓WO〓/SiO〓 catalyst can not be found, but it can be adsorbed on outgassed silica at 173K. Such adsorption is formed by interaction of the adsorbed methane with O〓〓 sites and hydroxyls on the surface. The appearance of the band at 2904cm〓 of the V〓 mode (sym. stretch.), which is an infrared forbidden vibration, implies that the Td symmetry of the methane molecule may be distorted somewhat on the surface of silica. The small frequency shift (30cm〓) of OH stretching indicates that only a weak hydrogen-bonding interaction between adsorbed methane and hydroxyls exists in the methane adsorption.

甲烷不能在Mn2O3-Na2WO4/SiO2催化剂上吸附但在l73K的温度条件下可吸附于SiO〓表面上，这种吸附是通过吸附甲烷与表面配位不饱和氧和表面羟基作用而形成的，红外禁阻的V〓振动模式显示出红外活性说明甲烷分子的Td对称性发生畸变，甲烷吸附后羟基位移只有30cm〓，吸附甲烷同表面羟基间的氢键作用很弱。

The phenyl acetate was synthesized from phenyl hydroxide and acetyl chloride by direct esterification and the factors influencing the synthesis were studied.Results showed that the optimal conditions were:n(C6H6O):n(C2H3OCl)=1:1.2,the amount of solvent cyclohexane was 40 mL(compared to 0.15 mol C6H6O),the reaction temperature was 20℃,and the reaction time was 5 h.

乙酸苯酯(分子式C8H8O2)是重要的药物中间体，它可以转化得到邻羟基苯乙酮和对羟基苯乙酮的混合物，可用于治疗急慢性黄疸型肝炎、胆囊炎等疾病，其中邻羟基苯乙酮是合成抗心律失常药盐酸普罗帕酮的重要中间体。

Common transparent quartz tube SiO2 more than 99.9% purity, geometry, chemical stability, thermal stability, resistance to thermal denaturation and anti-crystallization properties of the fine, optical transmittance above 93%; from hydroxyl in hydroxyl tube below 10ppm, after vacuum from hydroxyl, hydroxy-up to 5ppm below apply to high-pressure mercury lamp, sodium lamp, metal halide lamp, such as low-hydroxy products; white pipe, used mainly for heating tube, heating tube, far infrared control the manufacture, milky quartz pearl quartz tube possession of new technology, the management side as if the surface of pearls, all aspects of performance than ordinary white tube better; filter tube to filter out ultraviolet UV band in the harmful wavelengths of 190-320nm ultraviolet light source applied to environmental protection manufacturing; no ozone UV filter tube and pipe the contrary, through the ultraviolet wavelength around 253.7nm, there is no ozone UV lamp main material, widely used in medical equipment, water treatment, food hygiene, such as sterilization; quartz casing diameter 8-120mm in between, has a single opening, double opening round, flat-top shape and widen the mouth of necking, flanging, sanding and other processing, high temperature resistance, corrosion resistance, good light transmission and moisture-proof, explosion-proof characteristics such as widely used in aquarium thermostat, disinfection equipment, heating pipes, water treatment, metal halide lamp, such as product manufacturing and environmental protection, health, chemical and other fields; quartz Clamshell specifications 8-180mm, the shape according to the customer requirements, the bubble shell can take capillary has to carry out the exhaust, high temperature, light transmission is good, mainly for JC, JD, H1-H7, the stage lights and high-pressure mercury lamp, sodium lamp, metal halide lamp, such as product manufacturing; quartz water jacket mainly used in printing and packaging processing industry ---- UV light-curing, UV light curing is a very reliable and can be used to replace hot air dryers and other drying technique of curing technology, which in the printing and packaging of the processing industry has been widely.

普通透明石英管SiO2纯度达99.9%以上，几何尺寸、化学稳定性、热稳定性、抗热变性和抗析晶性能优良，光学透过率达93%以上；脱羟管羟基在10ppm以下，经过真空脱羟，羟基可达5ppm以下，适用于高压汞灯、钠灯、金卤灯等低羟基产品；乳白管，主要用于发热管、加热管、远红外管的制造，珠光石英管乳白石英管之新工艺，管面好象珍珠的表面，各方面性能比普通乳白管更优；滤紫外线管能够滤除紫外光谱波段中对人体有害的190-320nm波长的紫外线，适用于环保光源的制造；无臭氧管与滤紫外线管相反，可透过253.7nm左右波长的紫外线，是无臭氧紫外线杀菌灯的主要材料，广泛用于医疗器械、水处理、食品卫生等杀菌；石英套管直径范围在8-120mm之间，有单开口、双开口、圆头、平头等外形和扩口、缩口、翻边、磨砂等加工，具有耐高温、耐腐蚀、透光性好及防潮、防爆等特点，广泛使用于水族恒温器、消毒设备、加热管、水处理、金卤灯等产品的制造和环保、卫生、化工等领域；石英泡壳规格Φ8-180mm，形状根据客户要求，泡壳上可以接有毛细管，可进行排气，耐高温，透光性好，主要用于JC、JD、H1-H7、舞台灯和高压汞灯、钠灯、金卤灯等产品的制造；石英水套主要用于印刷和包装加工工业---- UV光固化， UV光固化是一种十分可靠的、可取代热空气干燥机和其他干燥技术的固化技术，它在印刷和包装加工工业已经得到广泛应用。

In the second part, quantum chemical AM1 methods were employedto theoretically investigate the electronic structures of maleic anhydride in ground- and excited-states. On basis of the frontier orbital theoryand three bonding principles, the possibility of reaction of active α-hydroxysuccinic anhydride carbanion and active α-hydroxy-succinic anhydride radical on polymerization process of MArespectively by alkali catalyst and by hydroxyl radical was discussed. Theanionic and radical polymerization of MA discussed also. Theoreticalstudies show that both polymerization products of MA are in the chainstructures, corresponding to the experimental findings.

第二部分用量子化学AM1方法，计算研究了马来酸酐的基态和激发态电子结构；应用前线轨道理论和成键三原则分别探讨了碱催化条件下和羟基自由基引发下马来酸酐均聚合过程中α-羟基丁二酸酐碳阴离子和α-羟基丁二酸酐碳自由基活性中间体参与反应的可能性及由它们引发的马来酸酐阴离子聚合反应机理和自由基引发聚合反应机理；理论研究表明马来酸酐的均聚合产物均为链式结构，与实验事实相相符。

According to the invention, the natural substances in question are selected from: hydroxy-cinnamic acids and the esters and depsides thereof; plant phenols which can be derived from hydroxy-cinnamic acids; polymers of hydroxy-cinnamic alcohols; other natural substances of plant origin which have anti-mutagenic and aromatising properties and are combined with anti-oxydant vitamins or with the precursors and/or derivatives thereof; and other anti-oxidant vitamins which are made to form complexes with eucaryotic cell cultures.

按照本发明，这些天然物质选自羟基肉桂酸及其酯和缩酚酸、可以由羟基肉桂酸衍生得到的植物酚、羟基肉桂醇的聚合物、具有抗诱变性和芳化性质的并且与维生素合用的其他植物源天然物质、以及与真核细胞培养物络合的其他抗氧化性维生素。

The extracts of water and alcohol were separated by ion exchange resin. The eluates of neutral solution were the most effective against hydroxyl radicals and the highest rate of inhibiting hydroxyl radicals was 81%. The eluates of basic solution were also effective, the inhibit rate of which was 60%.

将发酵灵芝粉的水和醇提取物上离子交换树脂柱，依次用酸性、中性、碱性淋洗液洗脱分组，发现中性洗脱部分对羟基自由基抑制作用最强，抑制率最高可达81％；碱性洗脱部分亦具有抑制羟基自由基的效果；酸性洗脱部分抑制羟基自由基的作用不强，且占很少比例。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。