羟基

Dihydroxy-7, 4′-dimethoxy-dihydrflavonol and -3, 5, 7 -trihydroxy-4′-methoxy- dihydrflavonol were synthesized by selective protection, condensation, epoxidation, cyclization and deprotection from 2, 4, 6-trihydroxyacetophone and anisaldehyde.

以2，4，6-三羟基苯乙酮和茴香醛为起始原料，经选择性保护、缩合、环氧化、关环等步骤首次完成了-3，5-二羟基-7，4′-二甲氧基二氢黄酮醇和-3，5，7-三羟基-4′-甲氧基二氢黄酮醇全合成。

Amount of auxochrome phenolic hydroxyl(0.29 unit/C9)in lignin from H_2O_2 bleaching chemi-mechanical pulp is slightly higher than one of material(0.28 unit/C9), so amount of auxochrome phenolic hydroxyl can not be effectively decreased by alkaline peroxide bleaching process.

麦草化学机械浆纸浆经过碱性H_2O_2漂白，木质素中酚羟基含量(0.29个/C9)略高于原料中的酚羟基含量(0.28个/C9)，说明H_2O_2漂白不能有效地减少木质素中酚羟基这类助色基团的数量。

Quercetin is one of the effective components contained in sophora japonica flower bud.3-hydroxy 4-carbonyl,4-carbonyl 5-hydroxy,and 3′,4′-dihydroxy groups of quercetin could be become chelating position with metal.

槲皮素（3，5，7，3′，4′－五羟基黄酮）是中药槐花蕾的有效成分之一。槲皮素的3－羟基4－酮基，5－羟基4－酮基及3′，4′－二羟基均为可络合部位。

Chapter 2 has analysized the conversly synthetic means of solanesol and designed novelly synthetic routes of solanesol and key intermediate Chapter 3 has summarized the preparation of trans-3-methyl-4-hydroxy (bromo-2-butenyl oxy methyl benzene In chapter 4 ,a novel technology of important intermediate(all trans-8-bromo geranyl acetate),which is suitable for industrial procedure , was found .meanwhile,an another new way has been invented ,of which the key intermediate (all trans-8-hydroxy geranyl acetate) has been produced.

第二部分分析了茄尼醇的逆合成方法，设计了一条适合于合成茄尼醇的合成路线及其重要中间体的合成路线。第三部分研究了重要中间体[Trans-3-甲基-4-羟基-2-丁烯基乙酰基(苄基，2，3-二氢吡喃基)醚]的合成新方法，找到了一条适合于工业化生产的制备反式-3-甲基-4-羟基-2-丁烯基苄基醚的新方法。第四部分研究了重要中间体[-3，7-二甲基-8-羟基-2，6-辛二烯-1-醇乙酸酯、-3，7-二甲基-8-溴-2，6-辛二烯-1-醇乙酸酯]的合成新方法，找到了一条适合于工业化生产的制备它们的新方法；同时研究了一条制备-3，7-二甲基-8-羟基-2，6-辛二烯-1-醇乙酸酯的另一新方法。

The invention discloses a method for expressing polyhydroxy fatty acid ester and a specific project bacterial, wherein the project bacterial for expressing polyhydroxy fatty acid ester is the mutant of the polyhydroxy fatty acid ester bacterial by inhibiting or removing a or a plurality genes related to fatty acid beta oxidization metabolic pathway in the polyhydroxy fatty acid ester bacterial.

本发明公开了聚羟基脂肪酸酯的一种表达方法及其专用工程菌。该用于表达聚羟基脂肪酸酯的工程菌是抑制或敲除产聚羟基脂肪酸酯细菌中的与脂肪酸β氧化代谢途径相关的一个或多个基因后得到的产聚羟基脂肪酸酯菌突变株。

The products were identified by IR,NMR,MS and elemental analysis. In our method,K.OH was used in place of NaOH to synthesize benzyl ester of 3,5-dimethyl-4-hydroxybenzoic acid,2',6'-dimethyl-4'-(n-succinimidyloxycarbonyl) phenyl-acridinium-9-carboxylate was purified on a silica gel column with chloroform/ethylacetate(4:l,v/v) as eluent and further purified by triturating with hexane/acetone(2:l,v/v).The luminescence produced by DMAE-NHS is a flash light with maximumemission at 0.4s and decay half-time of 0.9s. The luminescence intensity is 6.11x10 cps/mol,which is affected by the composition of trigger and surfactant.

DMAE·NHS的合成是本论文的关键和难点，我们对文献方法进行改进：文献方法用氢氧化钠与3，5-二甲基-4-羟基苯甲酸反应制得3，5-甲基-4-羟基苯甲酸钠，再用3，5-二甲基-4-羟基苯甲酸钠与苄氯作用制备3，5-二甲基-4-羟基苯甲酸苄酯，我们用氢氧化钾代替氢氧化钠，使合成取得成功；在合成2'，6'-二甲基-4'-苯基-吖啶-9-甲酸酯时，文献方法对粗产品进行两次硅胶柱层析纯化，第一次柱层析用氯仿/乙酸乙酯(4：1，Ⅴ：Ⅴ)作溶剂和淋洗剂，第二次柱层析用己烷/丙酮(2：1，Ⅴ：Ⅴ)作溶剂和淋洗剂，按照文献方法得到的不是所需要的化合物，我们只进行第一次柱层析纯化，然后用己烷/丙酮(2：1，Ⅴ：Ⅴ)进行研磨，过滤，洗涤，除去溶于己烷/丙酮(2：1，Ⅴ：Ⅴ)的部分，得到所需要的产品。

A synthesis method of 2-(2'-hydroxyl-4'-benzoyloxy-phenyl)-2H-benzotriazole and derivatives thereof is provided, and is characterized in that 2-(2', 4'-dihydroxyphenyl)-5-X-2H-benzotriazole and benzoyl chloride are taken as raw materials for reaction in solvent for 1-8 hours under the temperature of 50-140 DEC C with the mole ratio of 1 to 0.95-1.1, wherein, the amount of the solvent is 2 to 20 times that of the 2-(2', 4'-dihydroxyphenyl)-5-X-2H-benzotriazole and X represents H, F, Cl, Br.

一种2-(2′-羟基-4′-苯甲酸基苯基)-2H-苯并三唑及其衍生物的合成方法，其特征是，以2-(2′，4′-二羟基苯基)-5-X-2H-苯并三唑和苯甲酰氯为原料，在溶剂中进行反应，反应温度50℃～140℃，反应时间1～8小时，反应原料摩尔比2-(2′，4′-二羟基苯基)-5-X-2H-苯并三唑∶苯甲酰氯为1∶0.95～1.1，溶剂用量为2-(2′，4′-二羟基苯基)-5-X-2H-苯并三唑重量的2～20倍，其中X代表H、F、Cl、Br，具有反应条件温和、反应收率高和产物纯度高的特点。

There are some isomeric compounds of hydroxypyridinone. The compounds of 2-hydroxy-6-pyridinone have been used to dyestuff and pesticide widely. The compounds of 3-hydroxy-2-pyridinone and 3-hydroxy-4-pyridinone are paid attention to, because they are very useful heavy metal chelations. Especially, they are wonderful candidate medicament for the toxicosis of depleted uranium, so they can settle the DU jeopardize to the people.

羟基吡啶酮化合物有不同的同分异构体，2-羟基-6-吡啶酮已被广泛用于染料和农药行业，而3-羟基-2-吡啶酮和3-羟基-4-吡啶酮也引起了人们的重视，因为这两种异构体的化合物是非常理想的重金属络合剂，尤其重要的是，它可作为解决贫铀中毒的候选药物，有望解决战争中由于贫铀中毒带来的危害。

They are 2,7-dihydroxy-1,5,6-trimethoxy-9,10-phenanthrene,p-hydroxy phenyl aldehyde, 4-Hydroxybenzyl alcohol, Protocatechuic aldehyde, Gastrodin, 4,4'-Dihydroxydiphenylmethane,4-(4-(hydroxym-ethyl)phenoxymethylphenol,Isorhamnetin-3-O-glucoside,Isorhamnetin-3,7-di-O–glucoside, Imbricatin,2,3-dihydroxy-7-methoxy-9,10-dihydrophenanthropyrone, Cyclopholidone,Cyclopholidonol and β-daucosterol.

分别为：2，7-二羟基-1，5，6-三甲氧基-9，10-二氢菲，对羟基苯甲醛、天麻苷元、原儿茶醛、天麻素、4-（4-羟基-苄基）苯酚、4(4-苯氧基甲基苯酚、异鼠李素-3-O-葡萄糖苷、异鼠李素-3-O-7-O-二葡萄糖苷、Imbricatin、2，7-二羟基-3-甲氧基-9，10-二氢菲吡喃酮、Cyclopholidone、Cyclopholidonol和β-胡萝卜苷。

The reaction catalyzed by DAK converts DHA into dihydroxyacetone phosphate which is no toxic and can be ustilized by yeast cells. DAK presents in most organisms. DAK genes in the Saccharmyces cerevisiae and P. pastoris were cloned and characterized by a combined genetic and biochemical approach and the proteins encoded by these DAK genes are homodimer.

二羟基丙酮对酵母细胞来说是种有毒的化合物，在酵母菌中二羟基丙酮激酶参与二羟基丙酮的脱毒作用，DAK催化的反应使二羟基丙酮磷酸化，形成无毒性的磷酸二羟丙酮，可为酵母细胞所利用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。