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Pulsed release pellets of DS were prepared by using low-substituted hydroxyprolcelluloseas inner swelling layer and aqueous ethycellulose dispersion-Surelease as outer controlled membrane on a mini-fluidized bed spray coater.

采用微型流化床包衣设备,以低取代羟丙基纤维素为内层溶胀层材料、乙基纤维素水分散体为外层控释层材料制备了双层衣膜的包衣微丸,并对包衣工艺和影响药物释放的因素进行了考察。

Dimethicone ,Cyclopentasiloxane,Dimethicone/Vinyl Dimethicone Crosspolymer,Polysilicone-11,Glycoproteins,Panax Ginseng Root Extract,Equisetum Arvense Extract,Silica Dimethyl Silylate ,Bisabolol,Tocopheryl Acetate ,Sodium Hyaluronate,Ursolic Acid,Atelocollagen,Sodium Chondroitin Sulfate,Ethylhexyl Methoxycinnamate,Polyglyceryl-2 Tetraisostearate ,Glycerin ,Water,Alcohol,Butylene Glycol ,Lecithin,Xanthan Gum ,Mica,Fragrance ,Benzyl Alcohol,Linalool ,Hydroxycitronellal,Alpha-Isomethyl Ionone ,Amyl Cinnamal,Hexyl Cinnamal,Palm Tree Extract,Geraniol,Benzyl Benzoate,Butylphenyl Methylpropional,Phenoxyethanol,Methylparaben,Isopropylparaben,Butylparaben ,Isobutyl Paraben,Titanium Dioxide,Carmine

地美司康,环戊硅氧烷,聚二甲基硅氧烷/乙烯基聚二甲硅氧烷交联聚合物,聚硅氧烷-11,糖蛋白,人参根萃取,问荆萃取,二甲基甲硅烷基化硅石,没药醇,醋酸盐维他命E,透明质酸钠,熊果酸,去端肽胶原,硫酸盐软骨素,4-甲氧基肉桂酸-2-乙基己基酯,聚甘油-2 四异硬脂酸酯,甘油,水,酒精,丁二醇,卵磷脂,山羊胶,云母,香料,苯甲醇,沉香醇,羟基香茅醛,α异甲基紫罗酮,戊基肉桂醛,己基肉桂醛,棕榈树萃取,香叶醇,苯甲酸苯甲酯,丁苯基甲基丙醛,苯氧乙醇,羟苯甲酯,羟苯丙酯,羟苯丁酯,二氧化钛,胭脂虫红

Water,c12-20 acid peg-8 ester,octyldodecanol,propylene glycol,coco-caprylate/caprate,cetearyl isononanoate,prunus amygdalus dulcisoil,biosaccharide gum-1,phenoxyethanol,ethylhexyl methoxycinnamate,potassium cetyl phosphate,simmondsia chinensisseed oil,carbomer,glyceryl polymethacrylate,malva sylvestrisextract,glyceryl stearate,cetearyl alcohol,cetyl palmitate,cocoglycerides,c12-13 alkyl lactate,methylparaben,sorbic acid,disodium edta,sodium hydroxide,tocopheryl acetate,benzophenone-3,iris germanica root extract,retinyl palmitate,butylparaben,peg-8,propylparaben,ethylparaben,sodium hyaluronate,chlorhexidine digluconate,tocopherol,ascorbyl palmitate,citric acid,ascorbic acid

水, c12-20 acid peg-8 ester,辛基十二烷醇,丙二醇,coco-caprylate/caprate,鲸蜡硬脂醇异壬酸酯,甜杏仁油,多醣物质,苯氧乙醇,4-甲氧基肉桂酸-2-乙基己基酯,十六烷基磷酸钾,西蒙得木籽油,卡波姆,甘油聚甲基丙烯酸酯,锦葵萃取,甘油硬脂酸,棕榈醇,十六烷基棕榈酸酯,椰油脂酸甘油酯类,c12-13烷醇乳酸酯,对羟基苯甲酸甲酯,山梨酸,乙二胺四乙酸二钠,氢氧化钠,维生素E醋酸酯,二苯甲酮-3,鸢尾花萃取,维他命A酯,对羟基苯甲酸丁酯,聚乙二醇-8,羟苯丙酯,羟苯乙酯,透明质酸钠,洗必泰葡萄糖酸盐,维生素E ,维生素C棕榈酸酯,柠檬酸,抗坏血酸

Water、alcohol denat.、glycerin、butylene glycol、alanine、sucrose、urea、peg-60 hydrogenated castor oil、triethanolamine、allantoin、limonene、hamamelis virginiana extract、linalool、menthoxypropanediol、propylene glycol、alpha-isomethyl ionone、aspartic acid、acrylates/c10-30 alkyl acrylate crosspolymer、bisabolol、citronellol、fructose、glucose、glutamic acid、hexylene glycol、dextrin、hexyl nicotinate、fragranceparfum

水、双丙甘醇、变性乙醇、甘油、聚乙二醇-75、丁二醇、麦芽糖醇、PEG-60氢化蓖麻油、透明质酸钠、聚山梨醇酯-20、杏汁、乙醇、乳酸菌/梨汁发酵过滤液、磷酸氢二钠、乙基葡糖苷、羟丙基甲基纤维素、磷酸钾、黄原胶、豆瓣菜提取物、EDTA二钠、香精、茶叶提取物、苯氧乙醇。

Nine new compounds were characterized, and they were: opuntioside Ⅰ(11), 4-ethoxyl-6-hydroxymethyl-α-pyrone (14),--ester (22), 1-butoxyl--malate (24), ethyl α-L-rhamnopyranoside (26), opuntioside Ⅱ(34), kaempferol 7-O-β-D-glucopyranosyl (1→4)-β-D-glucopyranoside (46), methyl α-D-glucopyranoside-6-(methyl 4-malate)-ester (47), and opuntioside Ⅲ(48). Opuntioside Ⅰ,Ⅱ,Ⅲ and 4-ethoxyl-6-hydroxymethyl-α-pyrone belong to the skelecton of α-pyrone.

新化合物分别是:仙人掌苷Ⅰ(11),4-乙氧基-6-羟甲基-α-吡喃酮(14),琥珀酸乙酯--酯(22),L--苹果酸-1-丁酯(24),乙基α-L-吡喃鼠李糖苷(26),仙人掌苷Ⅱ(34),山奈酚7-O-β-D-吡喃葡萄糖基(1→4)-β-D-吡喃葡萄糖苷(46),α-D-吡喃葡萄糖甲苷-6-(苹果酸-4-甲酯)-酯(47),仙人掌苷Ⅲ(48),其中仙人掌苷Ⅰ、Ⅱ、Ⅲ及4-乙氧基-6-羟甲基-α-吡喃酮均为α-吡喃酮骨架类型的新化合物。

Nitratomethyl-3-ethyloxetane was synthesized by the process of cyclization, nitation from trimethlolpropane and diethyl carbonate, and the homopolymer of 3-nitratomethyl-3-ethyloxetane was synthesized with 1,4-butanediol as initator and boron trifluoride etherate as an catalyst by cationic ring-opening polymerization.

以三羟-甲基丙烷和碳酸二乙酯为原料经环化、硝化两步反应合成了化合物3-硝酸酯甲基-3-乙基氧丁环;采用1,4-丁二醇为引发剂,三氟化硼乙醚(BF3Et2O)为催化剂,NIMEO发生阳离子开环聚合得到一种端羟硝酸酯均聚醚PNIMEO。

Water,dimethicone,propylene glycol,glycerin,cyclomethicone,ppg-15 stearyl ether,sorbitan oleate,stearic acid,cetyl alcohol,glyceryl stearate,ethylhexyl methoxycinnamate,peg-100 stearate,panthenol,phenoxyethanol,phospholipids,triethanolamine,methylparaben,oenothera biennis oil,imidazolidinyl urea,carbomer,c12-13 alkyl lactate,glycyrrhetinic acid,citrus aurantium dulcisoil,propylparaben,tocopheryl acetate,benzophenone-3,triclosan,disodium edta,ethylparaben,pentadecalactone,iris germanica root extract,retinyl palmitate,bisabolol,butylparaben,sodium hyaluronate,aesculus hippocastanumseed extract,ruscus aculeatus root extract,chlorhexidine digluconate,biosaccharide gum-1,citrus aurantium amaraoil,tocopherol,lecithin,ascorbyl palmitate,glyceryl oleate,BHT,citric acid,limonene,linalool

水, 地美司康,丙二醇,甘油,环甲硅脂, PPG-15 硬脂基醚,油酸己六酯,硬脂酸,十六醇,甘油硬脂酸, 4-甲氧基肉桂酸-2-乙基己基酯,聚乙二醇硬脂酸酯,维生素B5,苯氧乙醇,磷脂质,三乙醇胺,羟苯甲酯,月见草油,尿素醛,卡波姆, c12-13烷醇乳酸酯,甘草亭酸,甜橙油,羟苯丙酯,醋酸盐维他命E,二苯酮-3,玉洁新,乙酸乙二胺二钠,羟苯乙酯,环十五内酯,鸢尾花根萃取,维他命A酯,没药醇,羟苯丁酯,透明质酸钠,欧洲七叶树籽萃取,假叶树根萃取,洗必泰葡萄糖酸盐,多醣物质,苦橙油,维生素E,卵燐脂,抗坏血酸棕榈酸酯,甘油油酸酯,二丁基羟基甲苯,柠檬酸,柠檬精油,芳樟醇水:几乎所有护肤品成分第一位都是水。地美司康:即silicon,矽灵,一般添加于霜剂中,使用后皮肤手感光滑。该成分不可吸收。

Water,butylene glycol,cyclomethicone,VP/VA copolymer,glyceryl stearate,glycerin,ppg-15 stearyl ether,titanium dioxide,propylene glycol,cetyl alcohol,citrus aurantium dulcisfruit extract,saccharide isomerate,biosaccharide gum-1,ethoxydiglycol,peg-40 stearate,glycyrrhiza glabraroot extract,morus bombycis root extract,potassium cetyl phosphate,phenoxyethanol,c12-20 acid peg-8 ester,triethanolamine,prunus amygdalus dulcis oil,carbomer,caprylyl glycol,caffeine,disodium edta,methylparaben,chondrus crispus,butylparaben,iris germanica root extract,pentadecalactone,sodium polyacrylate,ethylparaben,sodium hyaluronate,peg-8,propylparaben,citric acid,chlorhexidine digluconate,tocopherol,ascorbyl palmitate,ascorbic acid

水,丁烯二醇,环甲硅脂,VP/VA共聚物,甘油基硬脂酸,甘油,ppg-15 stearyl ether,二氧化钛,丙二醇,十六烷基醇,橙子萃取物,天然异构寡糖, biosaccharde gum-1,乙基氧基乙二醇,聚乙二醇- 40硬脂酸,甘草根提取物,桑白皮根萃取,钾十六烷基磷酸盐,苯氧乙醇,c12-20 acid peg-8 ester,三乙醇胺,甜杏仁油,高分子胶,辛乙二醇,咖啡因,乙二胺四乙酸二钠,对羟基苯甲酸甲酯,卡拉胶,对羟基苯甲酸丁酯,鸢尾花根萃取, pentadecalactone ,聚丙烯酸钠,羟苯乙酯,透明质酸钠,聚乙二醇- 8,羟苯丙酯,柠檬酸,洗必泰葡萄糖酸盐,维生素E,维生素C棕榈酸酯,抗坏血酸

Water,butylene glycol,glycerin,glyceryl polymethacrylate,triethanolamine,carbomer,ppg-26-bueth-26,chondrus crispus,peg-40 hydrogenated castor oil,phenoxyethanol,imidazolidinyl urea,propylene glycol,benzophenone-4,retinyl palmitate,citrus aurantiudulcisoil,phospholipids,methylparaben,tocopheryl acetate,c12-23 alkyl lactate,disodium EDTA,centella asiatica extract,iris germanica root extract,pentadecalactone,aloe barbadensis leaf juice,mimosa tenuiflora bark extract,sodium hyaluronate,menthol,biosaccharide gum-1,citrus aurantium amara oil,propylparaben,methylchloroisothiazolinone,sodium benzoate,potassium sorbate,citric acid,calcium sorbate,methylisothiazolinone,butylparaben,ethylparaben,yellow 5(CI 19140),limonene,linalool

水,丁二醇,甘油,甘油聚甲基丙烯酸酯,三乙醇胺,卡波姆,PPG-26-丁醇聚醚-26,鹿角菜胶,PEG-40 氢化蓖麻油,苯氧乙醇,尿素醛,丙二醇,二苯酮-4,维他命A酯,甜橙油,磷脂质,羟苯甲酯,醋酸盐维他命E,C12-13 烷醇乳酸酯,乙二胺四乙基二钠,雷公根萃取,鸢尾花根萃取,环十五内酯,吉拉索芦荟叶汁,含羞草萃取,透明质酸钠,薄荷脑,多醣物质,苦橙油,羟苯丙酯,甲基氯异塞唑晽酮,苯甲酸钠,山梨酸钾,柠檬酸,山梨酸钙,甲基异噻唑啉酮,羟苯丁酯,羟苯乙酯,柠檬黄,柠檬精油,沈香醇水:几乎所有护肤品成分第一位都是水。丁二醇:保湿剂及溶剂,质地温和

Water,c12-20 acid peg-8 ester,octyldodecanol,cetearyl isononanoate,butylene glycol,biosaccaride gum-1,peg-40 hydrogenated caster oil,ethylhexyl menthoxycinnamate,phenoxyethanol,potassium cetyl phosphate,macadamia ternifolia seed oil,dimethicone,carbomer,propylene glycol,glyceryl stearate,cocoglycerides,butyrospermum parkii,c12-13 alkyl lactate,methylparaben,benzophenone-3,pentadecalactone,sorbic acid,citrus aurantium dulcis oil,sodium hydroxyde,tocopheryl acetate,disodium edta,iris germanica root extract,retinyl palmitate,equisetum arvense extract,butylparaben,peg-8,propylparaben,ethylparaben,sodium hyaluronate,chlorhexidine digluconate,citrus aurantium amaraoil,tocopherol,ascorbyl palmitate,citric acid,ascorbic acid,limonene,linalool

水,c12-20 acid peg-8 ester,辛基十二烷醇,鲸蜡硬脂醇异壬酸酯,丁烯二醇,多醣物质,PEG-40氢化蓖麻油,4-甲氧基肉桂酸-2-乙基己基酯,苯氧乙醇,十六烷基磷酸钾,澳洲胡桃子油,地美司康,卡波姆,丙烯乙二醇,甘油硬脂酸,椰油脂酸甘油酯类,牛油果,c12-13烷醇乳酸酯,对羟基苯甲酸甲酯,二苯甲酮-3 ,环十五内酯,山梨酸,甜橙油,氢氧化钠,维生素E醋酸酯,乙二胺四乙酸二钠,鸢尾花萃取,维他命A酯,问荆萃取,对羟基苯甲酸丁酯,聚乙二醇- 8,羟苯丙酯,羟苯乙酯,透明质酸钠,洗必泰葡萄糖酸盐,苦橙油,维生素E ,维生素C棕榈酸酯,柠檬酸,抗坏血酸,柠檬精油,沉香醇水:几乎所有护肤品成分第一位都是水。辛基十二烷醇:界面活性剂、乳化剂、稠化剂,有一定刺激性

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