网状坏死

We propose an outpatient procedure under local anesthesia for the correction of prominent ears. We fold the antihelix with an anterior scoring method via posterior approach. The cartilage is preserved to avoid a sharp antihelical fold, and the scar is concealed in the posterior auricular sulcus. All patients had satisfactory correction of the deformity and yet no significant complication.

我们经由耳朵后将对耳轮软骨前表面作一个网状的雕刻，然后将之向后翻转作为新的对耳轮，可以避免软骨切除后所产生不美观的转折，避免产生两耳不对称的情形，术后没有血肿或皮肤坏死的并发症，手术所产生的疤痕隐藏在耳朵后面，所有的病人对手术结果都很满意。

We propose an outpatient procedure under local anesthesia for the correction of prominent ears. We fold the antihelix with an anterior scoring method via posterior approach. The cartilage is preserved to avoid a sharp antihelical fold, and the scar is concealed in the posterior auricular sulcus. All patients had satisfactory correction of the deformity and yet no significant complication.关键词 prominent ears , otoplasty

我们经由耳朵后将对耳轮软骨前表面作一个网状的雕刻，然后将之向后翻转作为新的对耳轮，可以避免软骨切除后所产生不美观的转折，避免产生两耳不对称的情形，术后没有血肿或皮肤坏死的并发症，手术所产生的疤痕隐藏在耳朵后面，所有的病人对手术结果都很满意。

The crutching and walking function of the leg reconstructed at last Conclusion When all the necrotic intermuscular vessels and muscles except caput mediale of gastrocnemius were removed, the necmsis may be delayed by means of reticular collateral circulation among skin, deep and superficial fascia and tibia of the injured limb. However, the blood supply is very little, the severe ischemia wound and ischemia pain can't be healed.

除腓肠肌内侧头以外全小腿肌肉、肌间血管均坏死被切除时，小腿皮肤、深浅筋膜组织、腓肠肌内侧头肌瓣与胫骨内血供系统在踝以下所构成的网状侧支循环能为患足提供微量血供，延缓足的坏死，但仅凭这一微量血供无法治愈广泛贫血创面和顽固性肢体缺血痛。

We also have observed some organs pathological changes of juvenile Jian Carp, such as pancreas acinous gland and zymogen granules of acinous gland cell disappearing, intercellular substance hyperplasia and inflammatory cells soakage, hepatatrophia, liver cell granular or vacuolar degeneration and necrosis, karyolysis or pyknosis, glycogen granules decreasing, metanephros atrophy, metanephric canaliculus epithelium granular or vacuolar degeneration and necrosis, mitochondrion swelling and mitochondrion cristae disappearing, karyolysis, distal convolutal tubule microvilli desquamating, spleen marrow cell degeneration and necrosis, intercellular substance of spleen hyperplasia, spleen atresia, blood corpuscle disappearing.

后肾土黄色、淡褐色或苍白色，肾小管上皮细胞肿胀、颗粒或水泡变性、坏死，细胞内有大量血细胞流出，线粒体肿胀，嵴结构消失，细胞核溶解，肾间质甲状腺滤泡和拟淋巴细胞增生，远曲小管微绒毛脱落、管道细胞界限不清。心脏肌纤维肿胀、颗粒或空泡变性，严重的肌纤维溶解、变细或断裂，肌纤维间水肿、炎性细胞浸润，部分心肌细胞核浓缩。脾脏暗褐色，脾髓质细胞变性、坏死，拟淋巴细胞明显减少，淋巴细胞岛少见、岛中细胞成份减少，黑素巨噬细胞中心减少、体积缩小，脾脏网状基质水肿，脾窦闭锁，血细胞减少。

The model of brain concussion of rat can be established successfully using iron pendulum hitting device; 2. The spatial learning and memory deficits of the rats are detected by MWM in early period post-BC(from 1 to 3 days after BC); 3. Pycnosis degeneration or necrosis neurons of the cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation are identified in BC rats; 4. There are significantly changes in the number and activity of cholinergic neurons in the basal forebrain and brainstem reticular formation after BC; 5. The change of cerebral neurons and cholinergic neurons correlate with cognitive deficits in BC rats .

1、单摆式闭合性机械打击装置能成功建立脑震荡大鼠模型；2、脑震荡大鼠在MWM实验中出现早期空间认知行为障碍；3、脑震荡大鼠大脑皮质、背侧海马、齿状回和脑干网状结构出现程度不等的部分神经元固缩变性和不完全性坏死；4、脑震荡大鼠基底前脑、脑干网状结构ChAT活性表达有明显变化；5、脑震荡大鼠认知障碍与相关脑区神经元、胆碱能神经元的变化有关联。

Methods: A brain concussion was produced in rats using a simple pendulum device model. One control (n=12) and six experimental groups were used(n=12 in each group). The cerebral concussion groups were assigned to sacrifice times ranging from 1 day to 24days after injury.A Morris Water Maze memory paradigm was used to assess learning and memory function. Pycnosis degeneration or necrosis neurons in the locus cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation were observed and counted after brain concussion. Cholinergic neurons in the basal forebrain and brainstem reticular formation were identified and quantitated using choline acetyltransferase.

应用自制单摆式闭合性机械打击装置建立脑震荡大鼠模型；成年SD大鼠随机分为1个对照组(n=12)和6个脑震荡组(即伤后1、2、4、8、16、24d，n=12)；应用Morris水迷宫(Morris Water Maze，MWM)实验评价大鼠的学习记忆功能；用光镜对大鼠的上述脑区的固缩变性坏死细胞进行观察和计数；用免疫组化方法检测基底前脑和脑干网状结构的胆碱乙酰转移酶(cholin acetyltransferase，ChAT)阳性细胞的表达。

There were no statistically differences between the 8th~ 14thday, the 15th - 21th day post-BC and the control group. During the rt~24tkday post-BC , pycnosis degeneration or necrosis neurons of the locus cerebral cortex, dorsal hippocampus, dentate fornix were significantly increased, then decreased gradually, but recovered to normal by the 24thday after BC, and especially in parietal cortex and piriform cortex the necrosis neurons were significantly increased than temporal cortex , and there were no statistically difference berween the left and the right side. Pycnosis degeneration or necrosis neurons in the brainstem reticular formation were markedly increased in the 4thday after BC, and there were no statistically difference among the other groups and the control group.

与对照组相比，BC后在大脑皮质、背侧海马和齿状回部位，固缩变性和不完全坏死细胞数先显著增加(P＜0.05)，然后逐渐减少，至24d基本恢复正常；顶叶、梨状皮质比颞叶皮质变性坏死细胞多，差异有高度显著性(P＜0.01)；大脑左侧比右侧变性坏死细胞稍少但差异无显著性；在BC后4d，脑桥核、斜方体核平面的脑干网状结构中固缩变性和不完全坏死细胞数明显增多(P＜0.05)，其它组间无显著性差异。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失