缺氧的

One, the end that domestic oxygen cure treats to COPD patient and meaning are anoxic can cause cellular loss quickly, correct anoxic main to having the COPD patient that has disease of blood of sexual low oxygen effect, research shows LTOT ameliorable COPD accompanies the survival rate that breathes exhaustion patient chronically.

一、家庭氧疗对COPD患者治疗的目的及意义缺氧可迅速引起细胞损伤，纠正缺氧对具有进行性低氧血症的COPD患者具有重要功能，探究表明LTOT可改善COPD伴慢性呼吸衰竭患者的生存率。

Methods 0, 2.5, 5, 10, 15 and 20 μmol/L arsenious acid-treated human hepatocellular carcinoma HepG2 cells were cultured under hypoxia for 8 hours. The cell proliferation and cell viability was assayed by WST-8 and the trypan blue dye exclusion method. The expressions of HIF-1α in human hepatocellular carcinoma HepG2 cells were checked by RT-PCR and Western Blot.

以0、0.25、0.5、1、2和4μmol/L的亚砷酸处理人肝癌细胞HepG2缺氧环境中培养8h；1μmol/L的亚砷酸处理人肝癌细胞HepG2缺氧培养0~10h，WST-8法和台盼蓝染色法分析细胞增殖和活力，采用RT-PCR和Western Blot方法检测肝癌细胞中HIF-1α的表达。

Transplantation of BMSCs in neonate rats at 24 hours after HIBD has the maximal long-lasting ethological improvement, which is induced by brain damage, and the mechanism may be that early transplantation with BMSCs reduces effectively neuron necrosis and apoptosis, and is helpful for the migration and differentiation of BMSCs.

新生大鼠缺氧缺血性脑损伤后24 h接受骨髓基质细胞移植可最大程度改善脑损伤所导致的远期行为学障碍，其机制可能与早期移植可有效减轻神经元的坏死、凋亡，且有利于骨髓基质细胞的迁移、分化有关。关键词：骨髓基质细胞；细胞移植；缺氧；缺血；脑；新生大鼠

The mechanism might be elevated the HIF-la in histocyte through which accelerate the expression of EPO level, enhance the body's ability of carrying and transporting oxygen and increase the activity of key enzymes in glycolysis in hypoxia mice, and elevated the ATP level to remission the energy metabolism in hypoxia mice.

马齿苋总黄酮能够提高小鼠抗缺氧能力，机制可能通过提高组织HIF-1α含量，促进EPO表达，增加了血红蛋白的合成和红细胞的数量，增强机体携运氧能力，同时促进了无氧酵解进行，缓解了缺氧小鼠的能量代谢障碍。

The mechanism might be elevated the HIF-la in histocyte through which accelerate the expression of EPO level, enhance the bodys ability of carrying and transporting oxygen and increase the activity of key enzymes in glycolysis in hypoxia mice, and elevated the ATP level to remission the energy metabolism in hypoxia mice.

马齿苋总黄酮能够提高小鼠抗缺氧能力，机制可能通过提高组织HIF-1α含量，促进EPO表达，增加了血红蛋白的合成和红细胞的数量，增强机体携运氧能力，同时促进了无氧酵解进行，缓解了缺氧小鼠的能量代谢障碍。

Hypoxia is an important characteristic of neoplasma and some other diseases. For this reason, it is becoming an attractive research area to inhibit tumor growth by utilizing the hypoxia environment.

缺氧是包括肿瘤在内的许多疾病的重要特征，利用缺氧条件来选择性抑制肿瘤生长和演进是一个很有前途的研究方向。

Chronic hypoxia and MCT-induced pulmonary hypertension are associated with excess collagen deposition in pulmonary arteries; meanwhile, the muscularization of nonmuscular intra-aeinar arteries also plays an important role in maintenance of pulmonary hypertension.

1。在慢性缺氧和MCT诱发的肺动脉高压进展过程中，肺动脉壁胶原沉积过度，泡内动脉结构发生改变，动脉中层厚化，非肌性动脉肌性化。2.764-3能部分抑制胶原的过度沉积，降低缺氧性及野百合碱性肺动脉高压，从而逆转泡内动脉的结构改变。

Mutant mice than in wild-type controls, and tetrodotoxin or bicuculline application abolished the difference between the genotypes. Studies on human oligodendroglioma cells revealed that GABA played a protective role on Ca〓 overload induced by OGD or glutamate and phaclofen, GABA〓 receptor antagonist, could significantly block the protection.

结果表明：①电凝大脑中动脉后Ca〓2.3-／-鼠脑梗死率和缺血后运动障碍明显重于Ca〓2.3+／+鼠；②Ca〓2.3-／-鼠海马脑片CA1区缺氧后钙超载明显高于Ca〓2.3+／+鼠；③Na〓通道阻滞剂TTX和GABA〓受体阻断剂bicuculline可显著缩小遗传表型之间的差异；④GABA对缺氧无糖及谷氨酸所致的人胶质细胞瘤细胞Ca〓超载有明显的保护作用，此作用可被GABA〓受体阻断剂phaclofen拮抗。

We propose that dexfenfluramine can also inhibit hypoxia-induced pulmonary vascular remodeling via SERT activity and inhibition of hypoxia-induced p38 mitogen-activated protein kinase.

因此我们认为右旋酚氟拉明也能通过改变SERT的活性抑制缺氧诱导的肺血管重构和抑制缺氧诱导的p38细胞分裂素活化蛋白激酶

Using the hypoxic brain model, we expect this three-year project will give us answer about the value of Tc-99m HL 91 as a hypoxic marker, and will provide us better understanding of the uptake mechanism of Tc-99m HL 91 at the tissue, cell, and subcell level.

因此吾人预计此三年计画的研究成果将可以藉由脑部缺氧模式来证实及确认Tc-99m HL 91是否为一个具有潜力的侦测缺氧核医药物；除此之外，更希望对於Tc-99m HL 91在组织、细胞及次细胞层次的作用机制能够加以明了。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。